Matches in SemOpenAlex for { <https://semopenalex.org/work/W195908600> ?p ?o ?g. }
- W195908600 abstract "A considerable effort is currently underway to develop a malaria vaccine based on live Plasmodium falciparum sporozoites. The first requisite of a sporozoite vaccine is the guarantee of parasite arrest prior to the onset of the pathogenic blood stage. Immunisation with genetically attenuated parasites (GAP) that arrest in the liver forms a promising approach. Work in this thesis describes the development and characterisation of a P. berghei Δb9Δslarp GAP that fully arrests in the liver. Immunisation of multiple mouse strains with low numbers of Δb9Δslarp GAP resulted in sterile protection. The Δb9Δslarp GAP is there- fore the leading GAP vaccine candidate. Work in this the- sis further describes the effect of varying the parameters of sporozoite inoculation on parasite liver load. These findings provide a rationale for the design of clinical trials aimed at the administration of live attenuated P. falciparum sporozoites." @default.
- W195908600 created "2016-06-24" @default.
- W195908600 creator A5008388508 @default.
- W195908600 creator A5018157884 @default.
- W195908600 creator A5028813039 @default.
- W195908600 creator A5044305166 @default.
- W195908600 creator A5051736842 @default.
- W195908600 creator A5069553227 @default.
- W195908600 creator A5072615029 @default.
- W195908600 creator A5089496235 @default.
- W195908600 date "2013-04-01" @default.
- W195908600 modified "2023-09-27" @default.
- W195908600 title "Outdoor Mosquito Control Using Odour-Baited Devices: Development and Evaluation of a Potential New Strategy to Complement Indoor Malaria Prevention Methods" @default.
- W195908600 cites W1634182632 @default.
- W195908600 cites W1766969306 @default.
- W195908600 cites W1980875835 @default.
- W195908600 cites W1990021656 @default.
- W195908600 cites W1991677677 @default.
- W195908600 cites W1991750390 @default.
- W195908600 cites W1994793453 @default.
- W195908600 cites W2026708814 @default.
- W195908600 cites W2027274881 @default.
- W195908600 cites W2028264798 @default.
- W195908600 cites W2030956935 @default.
- W195908600 cites W2047807053 @default.
- W195908600 cites W2055995702 @default.
- W195908600 cites W2064885397 @default.
- W195908600 cites W2072240710 @default.
- W195908600 cites W2081532903 @default.
- W195908600 cites W2082185416 @default.
- W195908600 cites W2083165455 @default.
- W195908600 cites W2084527344 @default.
- W195908600 cites W2085066872 @default.
- W195908600 cites W2087246054 @default.
- W195908600 cites W2095952371 @default.
- W195908600 cites W2103610338 @default.
- W195908600 cites W2107812735 @default.
- W195908600 cites W2108449053 @default.
- W195908600 cites W2112162133 @default.
- W195908600 cites W2114944705 @default.
- W195908600 cites W2119272664 @default.
- W195908600 cites W2119684348 @default.
- W195908600 cites W2122838852 @default.
- W195908600 cites W2124464571 @default.
- W195908600 cites W2126256240 @default.
- W195908600 cites W2127249471 @default.
- W195908600 cites W2135547884 @default.
- W195908600 cites W2147851766 @default.
- W195908600 cites W2153242893 @default.
- W195908600 cites W2158755282 @default.
- W195908600 cites W2160289022 @default.
- W195908600 cites W2165395122 @default.
- W195908600 cites W2168455870 @default.
- W195908600 cites W2171317168 @default.
- W195908600 cites W2294237037 @default.
- W195908600 cites W2342792690 @default.
- W195908600 cites W2413002699 @default.
- W195908600 cites W76596421 @default.
- W195908600 cites W2264811880 @default.
- W195908600 hasPublicationYear "2013" @default.
- W195908600 type Work @default.
- W195908600 sameAs 195908600 @default.
- W195908600 citedByCount "0" @default.
- W195908600 crossrefType "journal-article" @default.
- W195908600 hasAuthorship W195908600A5008388508 @default.
- W195908600 hasAuthorship W195908600A5018157884 @default.
- W195908600 hasAuthorship W195908600A5028813039 @default.
- W195908600 hasAuthorship W195908600A5044305166 @default.
- W195908600 hasAuthorship W195908600A5051736842 @default.
- W195908600 hasAuthorship W195908600A5069553227 @default.
- W195908600 hasAuthorship W195908600A5072615029 @default.
- W195908600 hasAuthorship W195908600A5089496235 @default.
- W195908600 hasConcept C136764020 @default.
- W195908600 hasConcept C159047783 @default.
- W195908600 hasConcept C203014093 @default.
- W195908600 hasConcept C2777237215 @default.
- W195908600 hasConcept C2778048844 @default.
- W195908600 hasConcept C2778371730 @default.
- W195908600 hasConcept C2781034427 @default.
- W195908600 hasConcept C3019824283 @default.
- W195908600 hasConcept C41008148 @default.
- W195908600 hasConcept C71924100 @default.
- W195908600 hasConcept C71928629 @default.
- W195908600 hasConcept C86803240 @default.
- W195908600 hasConceptScore W195908600C136764020 @default.
- W195908600 hasConceptScore W195908600C159047783 @default.
- W195908600 hasConceptScore W195908600C203014093 @default.
- W195908600 hasConceptScore W195908600C2777237215 @default.
- W195908600 hasConceptScore W195908600C2778048844 @default.
- W195908600 hasConceptScore W195908600C2778371730 @default.
- W195908600 hasConceptScore W195908600C2781034427 @default.
- W195908600 hasConceptScore W195908600C3019824283 @default.
- W195908600 hasConceptScore W195908600C41008148 @default.
- W195908600 hasConceptScore W195908600C71924100 @default.
- W195908600 hasConceptScore W195908600C71928629 @default.
- W195908600 hasConceptScore W195908600C86803240 @default.
- W195908600 hasLocation W1959086001 @default.
- W195908600 hasOpenAccess W195908600 @default.
- W195908600 hasPrimaryLocation W1959086001 @default.
- W195908600 hasRelatedWork W1770391136 @default.