Matches in SemOpenAlex for { <https://semopenalex.org/work/W195984328> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W195984328 endingPage "9" @default.
- W195984328 startingPage "953" @default.
- W195984328 abstract "Swiss-Webster mice were exposed to diets containing 7 or 1000 microg aluminum (Al)/g as Al lactate from conception through maturity (45 days of age). This exposure has previously been shown to cause changes in CNS myelin composition and peroxidizability; in this study myelin sheath widths were measured. Initially, samples of epon embedded, toluidine blue stained cervical spinal cord sectioned at 0.5 mm were examined light microscopically. Qualitatively, Al-treated mice appeared to have a diffuse paleness in nerve tracts. No indication of myelin structural damage (splitting, degeneration) was noted. Quantitative microscopy was performed using images captured with Scion Image Dage 1.59 at 1000x with oil. Axon perimeters and sheaths were measured with NIH image using a standardized sampling pattern in the right medial dorsal and ventral regions of the cervical spinal cord in 6 mice (3 male, 3 female) per group. Mean myelin sheath widths were 16% smaller in the Al-treated group compared to controls (p=.03). There was no effect of sex or region (dorsal/ventral). Axon perimeters were also smaller on the average in the Al treated group but this difference was not significant (p=.16). The relationship between sheath width and axon diameter was similar in the two groups. The density of myelinated axons was greater in some areas for the Al-treated group. The data indicate that dietary aluminum exposure can interfere with myelination in the spinal cord." @default.
- W195984328 created "2016-06-24" @default.
- W195984328 creator A5023963480 @default.
- W195984328 creator A5059229018 @default.
- W195984328 date "1999-12-01" @default.
- W195984328 modified "2023-09-23" @default.
- W195984328 title "Morphometric studies of myelination in the spinal cord of mice exposed developmentally to aluminum." @default.
- W195984328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10693976" @default.
- W195984328 hasPublicationYear "1999" @default.
- W195984328 type Work @default.
- W195984328 sameAs 195984328 @default.
- W195984328 citedByCount "5" @default.
- W195984328 countsByYear W1959843282017 @default.
- W195984328 countsByYear W1959843282018 @default.
- W195984328 crossrefType "journal-article" @default.
- W195984328 hasAuthorship W195984328A5023963480 @default.
- W195984328 hasAuthorship W195984328A5059229018 @default.
- W195984328 hasConcept C105702510 @default.
- W195984328 hasConcept C134018914 @default.
- W195984328 hasConcept C140530291 @default.
- W195984328 hasConcept C141071460 @default.
- W195984328 hasConcept C142724271 @default.
- W195984328 hasConcept C169760540 @default.
- W195984328 hasConcept C185592680 @default.
- W195984328 hasConcept C2776993930 @default.
- W195984328 hasConcept C2778609137 @default.
- W195984328 hasConcept C2779530196 @default.
- W195984328 hasConcept C2779632786 @default.
- W195984328 hasConcept C2780775167 @default.
- W195984328 hasConcept C3017789999 @default.
- W195984328 hasConcept C529278444 @default.
- W195984328 hasConcept C71924100 @default.
- W195984328 hasConcept C86803240 @default.
- W195984328 hasConceptScore W195984328C105702510 @default.
- W195984328 hasConceptScore W195984328C134018914 @default.
- W195984328 hasConceptScore W195984328C140530291 @default.
- W195984328 hasConceptScore W195984328C141071460 @default.
- W195984328 hasConceptScore W195984328C142724271 @default.
- W195984328 hasConceptScore W195984328C169760540 @default.
- W195984328 hasConceptScore W195984328C185592680 @default.
- W195984328 hasConceptScore W195984328C2776993930 @default.
- W195984328 hasConceptScore W195984328C2778609137 @default.
- W195984328 hasConceptScore W195984328C2779530196 @default.
- W195984328 hasConceptScore W195984328C2779632786 @default.
- W195984328 hasConceptScore W195984328C2780775167 @default.
- W195984328 hasConceptScore W195984328C3017789999 @default.
- W195984328 hasConceptScore W195984328C529278444 @default.
- W195984328 hasConceptScore W195984328C71924100 @default.
- W195984328 hasConceptScore W195984328C86803240 @default.
- W195984328 hasIssue "6" @default.
- W195984328 hasLocation W1959843281 @default.
- W195984328 hasOpenAccess W195984328 @default.
- W195984328 hasPrimaryLocation W1959843281 @default.
- W195984328 hasRelatedWork W1589619796 @default.
- W195984328 hasRelatedWork W195984328 @default.
- W195984328 hasRelatedWork W2056761515 @default.
- W195984328 hasRelatedWork W2065134331 @default.
- W195984328 hasRelatedWork W2095042676 @default.
- W195984328 hasRelatedWork W2360445779 @default.
- W195984328 hasRelatedWork W2411307525 @default.
- W195984328 hasRelatedWork W2413704030 @default.
- W195984328 hasRelatedWork W2510285772 @default.
- W195984328 hasRelatedWork W3148063430 @default.
- W195984328 hasVolume "20" @default.
- W195984328 isParatext "false" @default.
- W195984328 isRetracted "false" @default.
- W195984328 magId "195984328" @default.
- W195984328 workType "article" @default.