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• W1959884114 abstract "The effects of protein and protein-calorie malnutrition on the absorption of carbohydrates were studied in rats, by perfusion of intestinal segments in vivo using polyethylene glycol as a marker. Three types of diets were fed to 80-g male Wistar rats for 1 to 4 weeks: 1) CTL — 18% protein, 70% carbohydrates and 8% fat; 2) LPR — the same feeding with only 4% protein; and 3) LPC — low protein (4%) and low carbohydrate (45%). Failure to gain weight and hypoproteinemia were induced in the malnourished rats. The LPR and LPC rats had an increased intestinal transport of glucose compared to the CTL animals when this carbohydrate was perfused at a concentration of 69.5 and 139 mm after 14 days of the special diet. The apparent Km for glucose was 0.198 m for the LPR and 0.209 m for the LPC rats, as compared to 0.388 m for the CTL animals. However, LPR and LPC rats absorbed fructose and 3-O-methyl-D-glucose at a rate similar to CTL animals, suggesting that the intestine of malnourished rats utilized glucose at a higher rate. This increase did not occur after 7 and 28 days on the diet. The transport of sodium and water varied in the same direction as the transport of glucose. The transport of sucrose and maltose and the intestinal disaccharidase specific activity of the small intestine were not altered." @default.
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• W1959884114 date "1972-10-01" @default.
• W1959884114 modified "2023-10-18" @default.
• W1959884114 title "Absorption of Carbohydrates in Malnourished Rats" @default.
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• W1959884114 doi "https://doi.org/10.1093/jn/102.10.1303" @default.
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