Matches in SemOpenAlex for { <https://semopenalex.org/work/W19616145> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W19616145 endingPage "80" @default.
- W19616145 startingPage "2675" @default.
- W19616145 abstract "Fibromyalgia (FM) and chronic fatigue syndrome (CFS) are stress associated disorders mainly affecting women. FM is characterized primarily by widespread musculoskeletal pain, and CFS by profound debilitating fatigue, but there is considerable overlap of clinical symptoms between these 2 syndromes. Neuroendocrine abnormalities have been noted in both FM and CFS and desynchronization of circadian systems has been postulated in their etiology. The pineal hormone melatonin is involved in synchronizing circadian systems and the use of exogenous melatonin has become widespread in patients with FM and CFS.We examined the characteristics and relationship of melatonin and cortisol levels in premenopausal women with FM (n = 9) or CFS (n = 8), compared to age and menstrual cycle phase matched controls. Blood was collected from an indwelling intravenous catheter every 10 min over 24 h, and plasma melatonin and cortisol were determined by radioimmunoassay at 60 and 10 min intervals, respectively.Night time (23:00-06:50) plasma melatonin levels were significantly higher in FM patients compared to controls (p<0.05), but there was no significant difference in melatonin levels between CFS patients and controls. No differences in the timing of cortisol and melatonin secretory patterns and no internal desynchronization of the 2 rhythms were found in either patient group, compared to controls.Raised plasma melatonin concentrations have been documented in several other conditions that are associated with dysregulation of neuroendocrine axes. Increased melatonin levels may represent a marker of increased susceptibility to stress induced hypothalamic disruptions. These data indicate that there is no rationale for melatonin replacement therapy in patients with FM and CFS." @default.
- W19616145 created "2016-06-24" @default.
- W19616145 creator A5004064865 @default.
- W19616145 creator A5011826991 @default.
- W19616145 creator A5020709448 @default.
- W19616145 creator A5021461958 @default.
- W19616145 creator A5028412062 @default.
- W19616145 creator A5029723036 @default.
- W19616145 creator A5062562146 @default.
- W19616145 creator A5069490679 @default.
- W19616145 creator A5078128383 @default.
- W19616145 date "1999-12-01" @default.
- W19616145 modified "2023-09-27" @default.
- W19616145 title "Melatonin levels in women with fibromyalgia and chronic fatigue syndrome." @default.
- W19616145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10606381" @default.
- W19616145 hasPublicationYear "1999" @default.
- W19616145 type Work @default.
- W19616145 sameAs 19616145 @default.
- W19616145 citedByCount "37" @default.
- W19616145 countsByYear W196161452012 @default.
- W19616145 countsByYear W196161452014 @default.
- W19616145 countsByYear W196161452015 @default.
- W19616145 countsByYear W196161452017 @default.
- W19616145 countsByYear W196161452018 @default.
- W19616145 countsByYear W196161452019 @default.
- W19616145 countsByYear W196161452020 @default.
- W19616145 countsByYear W196161452021 @default.
- W19616145 countsByYear W196161452023 @default.
- W19616145 crossrefType "journal-article" @default.
- W19616145 hasAuthorship W19616145A5004064865 @default.
- W19616145 hasAuthorship W19616145A5011826991 @default.
- W19616145 hasAuthorship W19616145A5020709448 @default.
- W19616145 hasAuthorship W19616145A5021461958 @default.
- W19616145 hasAuthorship W19616145A5028412062 @default.
- W19616145 hasAuthorship W19616145A5029723036 @default.
- W19616145 hasAuthorship W19616145A5062562146 @default.
- W19616145 hasAuthorship W19616145A5069490679 @default.
- W19616145 hasAuthorship W19616145A5078128383 @default.
- W19616145 hasConcept C121446783 @default.
- W19616145 hasConcept C126322002 @default.
- W19616145 hasConcept C134018914 @default.
- W19616145 hasConcept C137627325 @default.
- W19616145 hasConcept C2777831278 @default.
- W19616145 hasConcept C2778182776 @default.
- W19616145 hasConcept C2779058012 @default.
- W19616145 hasConcept C2779566273 @default.
- W19616145 hasConcept C2780059843 @default.
- W19616145 hasConcept C71315377 @default.
- W19616145 hasConcept C71924100 @default.
- W19616145 hasConceptScore W19616145C121446783 @default.
- W19616145 hasConceptScore W19616145C126322002 @default.
- W19616145 hasConceptScore W19616145C134018914 @default.
- W19616145 hasConceptScore W19616145C137627325 @default.
- W19616145 hasConceptScore W19616145C2777831278 @default.
- W19616145 hasConceptScore W19616145C2778182776 @default.
- W19616145 hasConceptScore W19616145C2779058012 @default.
- W19616145 hasConceptScore W19616145C2779566273 @default.
- W19616145 hasConceptScore W19616145C2780059843 @default.
- W19616145 hasConceptScore W19616145C71315377 @default.
- W19616145 hasConceptScore W19616145C71924100 @default.
- W19616145 hasIssue "12" @default.
- W19616145 hasLocation W196161451 @default.
- W19616145 hasOpenAccess W19616145 @default.
- W19616145 hasPrimaryLocation W196161451 @default.
- W19616145 hasRelatedWork W19616145 @default.
- W19616145 hasRelatedWork W2009634330 @default.
- W19616145 hasRelatedWork W2009692691 @default.
- W19616145 hasRelatedWork W2046229009 @default.
- W19616145 hasRelatedWork W2068805819 @default.
- W19616145 hasRelatedWork W2092341993 @default.
- W19616145 hasRelatedWork W2120982894 @default.
- W19616145 hasRelatedWork W2434533728 @default.
- W19616145 hasRelatedWork W2797587270 @default.
- W19616145 hasRelatedWork W2891474850 @default.
- W19616145 hasVolume "26" @default.
- W19616145 isParatext "false" @default.
- W19616145 isRetracted "false" @default.
- W19616145 magId "19616145" @default.
- W19616145 workType "article" @default.