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- W1961855434 abstract "Abstract Protein kinases and protein phosphatases catalyze phosphorylation and dephosphorylation of cellular proteins. Posttranslational protein phosphorylation is a major mechanism of signal transduction in eukaryotes; it serves as a reversible switch that alters the activity of target proteins as a means to link stimuli to the appropriate cellular response. In this article, I will review the structures and mechanisms of protein kinases and phosphatases as well as describe chemical tools developed to study protein phosphorylation." @default.
- W1961855434 created "2016-06-24" @default.
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- W1961855434 date "2008-05-15" @default.
- W1961855434 modified "2023-10-10" @default.
- W1961855434 title "Kinases and Dephosphorylases: Chemistry and Roles" @default.
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- W1961855434 doi "https://doi.org/10.1002/9780470048672.wecb269" @default.
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