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- W1962024192 abstract "We describe a mother and son exhibiting a rare subtype of palmoplantar keratoderma, characterized by scleroatrophy, sclerodactyly, and nail anomalies. In the affected skin of the mother, 3 squamous cell carcinomas had developed at a young age. Retinoid treatment was started prophylactically. After the original description by Huriez et al. in 1963, six other families and one case report have been described. The palmoplantar keratoderma is usually mild. However, the distinctive feature of this syndrome is malignant degeneration of the affected skin at a young age. Furthermore, an unusually high mortality rate for this type of skin cancer of 5% has been reported. This case is described in order to underline the importance of accurate specification of each hereditary palmoplantar keratoderma. The characteristic clinical hallmarks of Huriez syndrome enable a rapid diagnosis. which is important for preventing malignant degeneration. Prophylaxis by retinoid treatment is discussed." @default.
- W1962024192 created "2016-06-24" @default.
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- W1962024192 date "2000-07-06" @default.
- W1962024192 modified "2023-09-29" @default.
- W1962024192 title "The Huriez syndrome. Scleroatrophic palmoplantar keratoderma" @default.
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