FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1962284334> ?p ?o ?g. }

• W1962284334 endingPage "872" @default.
• W1962284334 startingPage "867" @default.
• W1962284334 abstract "Pilocytic astrocytomas (PAs) are increasingly tested for KIAA1549-BRAF fusions. We used reverse transcription polymerase chain reaction for the 3 most common KIAA1549-BRAF fusions, together with BRAF V600E and histone H3.3 K27M analyses to identify relationships of these molecular characteristics with clinical features in a cohort of 32 PA patients. In this group, the overall BRAF fusion detection rate was 24 (75%). Ten (42%) of the 24 had the 16-9 fusion, 8 (33%) had only the 15-9 fusion, and 1 (4%) of the patients had only the 16-11 fusion. In the PAs with only the 15-9 fusion, 1 PA was in the cerebellum and 7 were centered in the midline outside of the cerebellum, that is, in the hypothalamus (n = 4), optic pathways (n = 2), and brainstem (n = 1). Tumors within the cerebellum were negatively associated with fusion 15-9. Seven (22%) of the 32 patients had tumor-related deaths and 25 of the patients (78%) were alive between 2 and 14 years after initial biopsy. Age, sex, tumor location, 16-9 fusion, and 15-9 fusion were not associated with overall survival. Thus, in this small cohort, 15-9 KIAA1549-BRAF fusion was associated with midline PAs located outside of the cerebellum; these tumors, which are generally difficult to resect, are prone to recurrence." @default.
• W1962284334 created "2016-06-24" @default.
• W1962284334 creator A5001840811 @default.
• W1962284334 creator A5003326768 @default.
• W1962284334 creator A5013348473 @default.
• W1962284334 creator A5039647180 @default.
• W1962284334 creator A5041298088 @default.
• W1962284334 creator A5043753285 @default.
• W1962284334 creator A5067287594 @default.
• W1962284334 creator A5076290364 @default.
• W1962284334 creator A5077977818 @default.
• W1962284334 creator A5083369819 @default.
• W1962284334 creator A5084126277 @default.
• W1962284334 creator A5084288716 @default.
• W1962284334 creator A5085771324 @default.
• W1962284334 creator A5086428373 @default.
• W1962284334 date "2015-09-01" @default.
• W1962284334 modified "2023-10-10" @default.
• W1962284334 title "BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum" @default.
• W1962284334 cites W1612891404 @default.
• W1962284334 cites W1895892633 @default.
• W1962284334 cites W1984629114 @default.
• W1962284334 cites W2017090190 @default.
• W1962284334 cites W2018395989 @default.
• W1962284334 cites W2024879713 @default.
• W1962284334 cites W2025238642 @default.
• W1962284334 cites W2035346960 @default.
• W1962284334 cites W2043023585 @default.
• W1962284334 cites W2045309144 @default.
• W1962284334 cites W2047867594 @default.
• W1962284334 cites W2047902204 @default.
• W1962284334 cites W2055475004 @default.
• W1962284334 cites W2055560959 @default.
• W1962284334 cites W2065155886 @default.
• W1962284334 cites W2075608121 @default.
• W1962284334 cites W2084378067 @default.
• W1962284334 cites W2110355778 @default.
• W1962284334 cites W2113535087 @default.
• W1962284334 cites W2120711389 @default.
• W1962284334 cites W2124664680 @default.
• W1962284334 cites W2127003779 @default.
• W1962284334 cites W2129554457 @default.
• W1962284334 cites W2130743512 @default.
• W1962284334 cites W2141355900 @default.
• W1962284334 cites W2149890572 @default.
• W1962284334 cites W2152219836 @default.
• W1962284334 cites W2165227865 @default.
• W1962284334 cites W2169438753 @default.
• W1962284334 cites W2171512544 @default.
• W1962284334 doi "https://doi.org/10.1097/nen.0000000000000226" @default.
• W1962284334 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4554227" @default.
• W1962284334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26222501" @default.
• W1962284334 hasPublicationYear "2015" @default.
• W1962284334 type Work @default.
• W1962284334 sameAs 1962284334 @default.
• W1962284334 citedByCount "45" @default.
• W1962284334 countsByYear W19622843342016 @default.
• W1962284334 countsByYear W19622843342017 @default.
• W1962284334 countsByYear W19622843342018 @default.
• W1962284334 countsByYear W19622843342019 @default.
• W1962284334 countsByYear W19622843342020 @default.
• W1962284334 countsByYear W19622843342021 @default.
• W1962284334 countsByYear W19622843342022 @default.
• W1962284334 countsByYear W19622843342023 @default.
• W1962284334 crossrefType "journal-article" @default.
• W1962284334 hasAuthorship W1962284334A5001840811 @default.
• W1962284334 hasAuthorship W1962284334A5003326768 @default.
• W1962284334 hasAuthorship W1962284334A5013348473 @default.
• W1962284334 hasAuthorship W1962284334A5039647180 @default.
• W1962284334 hasAuthorship W1962284334A5041298088 @default.
• W1962284334 hasAuthorship W1962284334A5043753285 @default.
• W1962284334 hasAuthorship W1962284334A5067287594 @default.
• W1962284334 hasAuthorship W1962284334A5076290364 @default.
• W1962284334 hasAuthorship W1962284334A5077977818 @default.
• W1962284334 hasAuthorship W1962284334A5083369819 @default.
• W1962284334 hasAuthorship W1962284334A5084126277 @default.
• W1962284334 hasAuthorship W1962284334A5084288716 @default.
• W1962284334 hasAuthorship W1962284334A5085771324 @default.
• W1962284334 hasAuthorship W1962284334A5086428373 @default.
• W1962284334 hasBestOaLocation W19622843341 @default.
• W1962284334 hasConcept C104317684 @default.
• W1962284334 hasConcept C111829193 @default.
• W1962284334 hasConcept C126322002 @default.
• W1962284334 hasConcept C142724271 @default.
• W1962284334 hasConcept C2777722931 @default.
• W1962284334 hasConcept C2778227246 @default.
• W1962284334 hasConcept C2778274637 @default.
• W1962284334 hasConcept C2778880634 @default.
• W1962284334 hasConcept C2779652256 @default.
• W1962284334 hasConcept C502942594 @default.
• W1962284334 hasConcept C54355233 @default.
• W1962284334 hasConcept C71924100 @default.
• W1962284334 hasConcept C86803240 @default.
• W1962284334 hasConceptScore W1962284334C104317684 @default.
• W1962284334 hasConceptScore W1962284334C111829193 @default.
• W1962284334 hasConceptScore W1962284334C126322002 @default.
• W1962284334 hasConceptScore W1962284334C142724271 @default.
• W1962284334 hasConceptScore W1962284334C2777722931 @default.

• next