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• W1962445534 abstract "There are conflicting data that suggest that hyperoxia may be associated with either worse or better outcomes in patients suffering a stroke.To investigate the association between PaO(2) in the first 24 hours in the intensive care unit and mortality among ventilated patients with acute ischaemic stroke.Retrospective cohort study.Data were extracted from the Australian and New Zealand Intensive Care Society Adult Patient Database.Adults ventilated for ischaemic stroke in 129 ICUs in Australia and New Zealand, 2000-2009.The primary outcome was the odds ratio for in hospital mortality associated with worst PaO(2) considered as a categorical variable, with data divided into deciles and compared with the mortality of the 10th decile. For patients on an FiO(2) of _50% at any time in the first 24 hours, worst PaO(2) was defined as the PaO(2) associated with the highest alveolar-arterial (A-a) gradient. For patients on an FiO(2) of <50%, it was defined as the lowest PaO(2). Secondary outcomes were ICU and hospital length of stay and the proportion of patients in each decile discharged home.Of the 2643 patients eligible for study inclusion, 1507 (57%) died in hospital. The median worst PaO(2) was 117mmHg (interquartile range, 87-196mmHg). There was no association between worst PaO(2) and mortality, length of stay or likelihood of discharge home.We found no association between worst arterial oxygen tension in the first 24 hours in ICU and outcome in ventilated patients with ischaemic stroke." @default.
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• W1962445534 date "2012-03-01" @default.
• W1962445534 modified "2023-10-03" @default.
• W1962445534 title "The association between early arterial oxygenation and mortality in ventilated patients with acute ischaemic stroke." @default.
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