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- W1962687615 abstract "Many attempts have been made to devise a simple and accurate laboratory method for determining the presence of toxic and antitoxic substances in the blood of persons suffering from acute infections of various kinds and in the blood of normal individuals. Several methods adapted for the study of certain toxins have resulted. Many of these in the hands of most workers have been difficult to manipulate. Others have failed to give the qualitative and quantitative data necessary. It has been evident since the beginning of the study of toxins and antitoxins that their presence or absence must be determined by testing their effect upon animal tissues. Other and more accurate methods will probably not be devised until the chemical and physical properties of these substances are better understood. For a long time it has seemed apparent that the tissue culture method might aid very materially in making such determinations." @default.
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- W1962687615 date "1919-01-01" @default.
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- W1962687615 title "The Study of Problems of Immunity by the Tissue Culture Method III. A Method for Determining the Resistance of Individuals to Diphtheria Infection" @default.
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