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- W1962733462 abstract "1148 Objectives Prognostic assessment in pts with CHF is difficult in clinical practice.The degree of functional impairment, reduced myocardial perfusion, myocites viability and the abnormally increased activation of sympathetic nervous system are important factors. Furthermore,beta-blocker medication has been demonstrated to improve LVEF and prognosis Methods 22 patients with CHF underwent a baseline investigation(rest 99mTc-MIBI Gated SPECT/CT,18F-FDG myocardial PET/CT and 123I-MIBG Myocardial imaging)and a follow-up(F.U.)rest99mTc-MIBI Gated SPECT/CT after 13,1+7,11 months therapy with Carvedilol. The subjects were divided into 3 groups.Gr-1: 10 pts with EF 40%(46±5,8% p Results W.O.rate and PET score seem to have an independent positive value in predicting beta-blocker therapy outcome more than H/M ratio. Conclusions Our preliminary results seem to demonstrate that MIBG imaging and FDG PET can help clinicians to identify responders to beta-blocker medication in pts with CHF" @default.
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- W1962733462 date "2011-05-01" @default.
- W1962733462 modified "2023-09-27" @default.
- W1962733462 title "Myocardial molecular imaging can be a useful tool to predict beta-blocker therapy outcome in congestive heart failure (CHF)" @default.
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