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- W1963033020 abstract "Myasthenia gravis is an autoimmune disease marked by neuromuscular transmission failure at the neuromuscular junction. Castleman disease is a rare lymphoproliferative disease characterized by non-cancerous angiofolicular hyperplasia of lymphatic tissue.We describe a young man with rapid, successive manifestations of myasthenia gravis, a solitary form of Castleman disease, pemphigus vulgaris, and anti-phospholipid syndrome, which resulted in 2 ischemic cerebrovascular events that caused a severe central neurological deficit.We were unable to find a similar case in the literature, but we hypothesize that the temporal concidence of these clinical entities may be related to a common immunological pathway, such as B-cell activation. Therefore, we treated the patient with an immunosuppressant and anticoagulant treatment, as well as rituximab, a monoclonal antibody therapy against CD20+." @default.
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- W1963033020 date "2013-02-06" @default.
- W1963033020 modified "2023-10-18" @default.
- W1963033020 title "Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome" @default.
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- W1963033020 doi "https://doi.org/10.1002/mus.23657" @default.
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