Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963350856> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W1963350856 abstract "Abstract We describe a method for the simultaneous liquid-chromatographic determination of ethosuximide, ethylphenacemide, primidone, phenobarbital, carbamazepine, and phenytoin in serum. The drugs, together with an internal standard, are extracted into ethyl acetate at pH 7.0. The extract is analyzed isocratically at ambient temperature on a reversed-phase column of SAS Hypersil with a mobile phase of acetonitrile/tetrabutyl ammonium phosphate solution (2/8 by volume). The eluted drugs are detected by their absorption at 200 nm, and quantitated from their peak heights as compared with those of extracted standards. The day-to-day CV of the method varied between 5.1 and 9.6% for concentrations ranging from less than therapeutic to toxic. The results, when compared with those by gas chromatography, gave correlation coefficients of 0.936 for phenytoin, 0.977 for phenobarbital, and 0.939 for primidone. No drug interference was found except that amobarbital and ethylphenacemide co-chromatographed." @default.
- W1963350856 created "2016-06-24" @default.
- W1963350856 creator A5015368248 @default.
- W1963350856 creator A5077394793 @default.
- W1963350856 date "1980-03-01" @default.
- W1963350856 modified "2023-09-23" @default.
- W1963350856 title "Measurement of anticonvulsants in serum by reversed-phase ion-pair liquid chromatography." @default.
- W1963350856 doi "https://doi.org/10.1093/clinchem/26.3.499" @default.
- W1963350856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7363472" @default.
- W1963350856 hasPublicationYear "1980" @default.
- W1963350856 type Work @default.
- W1963350856 sameAs 1963350856 @default.
- W1963350856 citedByCount "21" @default.
- W1963350856 countsByYear W19633508562016 @default.
- W1963350856 crossrefType "journal-article" @default.
- W1963350856 hasAuthorship W1963350856A5015368248 @default.
- W1963350856 hasAuthorship W1963350856A5077394793 @default.
- W1963350856 hasConcept C169760540 @default.
- W1963350856 hasConcept C179998833 @default.
- W1963350856 hasConcept C185592680 @default.
- W1963350856 hasConcept C2775858608 @default.
- W1963350856 hasConcept C2776077997 @default.
- W1963350856 hasConcept C2776918552 @default.
- W1963350856 hasConcept C2777463227 @default.
- W1963350856 hasConcept C2777992146 @default.
- W1963350856 hasConcept C2778186239 @default.
- W1963350856 hasConcept C2778337148 @default.
- W1963350856 hasConcept C2778793413 @default.
- W1963350856 hasConcept C2779253243 @default.
- W1963350856 hasConcept C2779619453 @default.
- W1963350856 hasConcept C2780782300 @default.
- W1963350856 hasConcept C43617362 @default.
- W1963350856 hasConcept C71924100 @default.
- W1963350856 hasConcept C73826308 @default.
- W1963350856 hasConcept C86803240 @default.
- W1963350856 hasConcept C98274493 @default.
- W1963350856 hasConceptScore W1963350856C169760540 @default.
- W1963350856 hasConceptScore W1963350856C179998833 @default.
- W1963350856 hasConceptScore W1963350856C185592680 @default.
- W1963350856 hasConceptScore W1963350856C2775858608 @default.
- W1963350856 hasConceptScore W1963350856C2776077997 @default.
- W1963350856 hasConceptScore W1963350856C2776918552 @default.
- W1963350856 hasConceptScore W1963350856C2777463227 @default.
- W1963350856 hasConceptScore W1963350856C2777992146 @default.
- W1963350856 hasConceptScore W1963350856C2778186239 @default.
- W1963350856 hasConceptScore W1963350856C2778337148 @default.
- W1963350856 hasConceptScore W1963350856C2778793413 @default.
- W1963350856 hasConceptScore W1963350856C2779253243 @default.
- W1963350856 hasConceptScore W1963350856C2779619453 @default.
- W1963350856 hasConceptScore W1963350856C2780782300 @default.
- W1963350856 hasConceptScore W1963350856C43617362 @default.
- W1963350856 hasConceptScore W1963350856C71924100 @default.
- W1963350856 hasConceptScore W1963350856C73826308 @default.
- W1963350856 hasConceptScore W1963350856C86803240 @default.
- W1963350856 hasConceptScore W1963350856C98274493 @default.
- W1963350856 hasLocation W19633508561 @default.
- W1963350856 hasLocation W19633508562 @default.
- W1963350856 hasOpenAccess W1963350856 @default.
- W1963350856 hasPrimaryLocation W19633508561 @default.
- W1963350856 hasRelatedWork W1945155729 @default.
- W1963350856 hasRelatedWork W1963350856 @default.
- W1963350856 hasRelatedWork W1978846860 @default.
- W1963350856 hasRelatedWork W2069745053 @default.
- W1963350856 hasRelatedWork W2079540690 @default.
- W1963350856 hasRelatedWork W2110346057 @default.
- W1963350856 hasRelatedWork W2122920501 @default.
- W1963350856 hasRelatedWork W2162773122 @default.
- W1963350856 hasRelatedWork W2169718081 @default.
- W1963350856 hasRelatedWork W4239888361 @default.
- W1963350856 isParatext "false" @default.
- W1963350856 isRetracted "false" @default.
- W1963350856 magId "1963350856" @default.
- W1963350856 workType "article" @default.