Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963399097> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W1963399097 endingPage "93" @default.
- W1963399097 startingPage "II88" @default.
- W1963399097 abstract "The effects of removal of endothelium and changes in blood flow in conscious dogs on the responses of large iliac artery diameter to local infusion of nitroglycerin, acetylcholine, epinephrine, and norepinephrine into the iliac artery were studied. Infusion of agonists did not change mean arterial pressure or heart rate. In vessels with intact endothelium, iliac diameter increased with nitroglycerin (5.1 +/- 0.5%), acetylcholine (4.5 +/- 0.5%), and epinephrine (3.5 +/- 0.9%) and decreased with norepinephrine (-6.7 +/- 1.7%). Preventing increases in blood flow during infusions of agonists abolished the dilation with epinephrine but not with nitroglycerin or acetylcholine. When blood flow was completely stopped by occlusion of the iliac artery, local injection of nitroglycerin (5.7 +/- 0.7%) and acetylcholine (3.0 +/- 0.6%) dilated, but epinephrine constricted (-9.1 +/- 1.7%), the iliac artery. Removal of the iliac artery endothelium did not change the dilation with nitroglycerin (4.6 +/- 0.5%), abolished the dilation with acetylcholine (0.0 +/- 0.3%), reversed the dilation with epinephrine to constriction (-3.3 +/- 0.7%), and enhanced the constriction with norepinephrine (-13.6 +/- 1.6%). These results indicate that epinephrine and acetylcholine dilate the iliac artery via a mechanism mediated by the endothelium. The endothelium-dependent dilation observed with epinephrine is mediated by an increase in iliac blood flow, while that observed with acetylcholine is due partially to a direct effect on the endothelium as well as an effect of blood flow superimposed on the direct effect. The results further indicate that the endothelium attenuates vasoconstriction produced by the alpha-adrenergic agonists, norepinephrine and epinephrine." @default.
- W1963399097 created "2016-06-24" @default.
- W1963399097 creator A5006283285 @default.
- W1963399097 creator A5051551818 @default.
- W1963399097 date "1987-11-01" @default.
- W1963399097 modified "2023-09-26" @default.
- W1963399097 title "Blood flow- and endothelium-mediated vasomotion of iliac arteries in conscious dogs." @default.
- W1963399097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3117408" @default.
- W1963399097 hasPublicationYear "1987" @default.
- W1963399097 type Work @default.
- W1963399097 sameAs 1963399097 @default.
- W1963399097 citedByCount "9" @default.
- W1963399097 crossrefType "journal-article" @default.
- W1963399097 hasAuthorship W1963399097A5006283285 @default.
- W1963399097 hasAuthorship W1963399097A5051551818 @default.
- W1963399097 hasConcept C126322002 @default.
- W1963399097 hasConcept C134018914 @default.
- W1963399097 hasConcept C141071460 @default.
- W1963399097 hasConcept C158846371 @default.
- W1963399097 hasConcept C164705383 @default.
- W1963399097 hasConcept C174940676 @default.
- W1963399097 hasConcept C2775859304 @default.
- W1963399097 hasConcept C2775910092 @default.
- W1963399097 hasConcept C2776820930 @default.
- W1963399097 hasConcept C2776992346 @default.
- W1963399097 hasConcept C2778514916 @default.
- W1963399097 hasConcept C2779959501 @default.
- W1963399097 hasConcept C3017865074 @default.
- W1963399097 hasConcept C42219234 @default.
- W1963399097 hasConcept C513476851 @default.
- W1963399097 hasConcept C71924100 @default.
- W1963399097 hasConceptScore W1963399097C126322002 @default.
- W1963399097 hasConceptScore W1963399097C134018914 @default.
- W1963399097 hasConceptScore W1963399097C141071460 @default.
- W1963399097 hasConceptScore W1963399097C158846371 @default.
- W1963399097 hasConceptScore W1963399097C164705383 @default.
- W1963399097 hasConceptScore W1963399097C174940676 @default.
- W1963399097 hasConceptScore W1963399097C2775859304 @default.
- W1963399097 hasConceptScore W1963399097C2775910092 @default.
- W1963399097 hasConceptScore W1963399097C2776820930 @default.
- W1963399097 hasConceptScore W1963399097C2776992346 @default.
- W1963399097 hasConceptScore W1963399097C2778514916 @default.
- W1963399097 hasConceptScore W1963399097C2779959501 @default.
- W1963399097 hasConceptScore W1963399097C3017865074 @default.
- W1963399097 hasConceptScore W1963399097C42219234 @default.
- W1963399097 hasConceptScore W1963399097C513476851 @default.
- W1963399097 hasConceptScore W1963399097C71924100 @default.
- W1963399097 hasIssue "5 Pt 2" @default.
- W1963399097 hasLocation W19633990971 @default.
- W1963399097 hasOpenAccess W1963399097 @default.
- W1963399097 hasPrimaryLocation W19633990971 @default.
- W1963399097 hasRelatedWork W1963399097 @default.
- W1963399097 hasRelatedWork W1963655719 @default.
- W1963399097 hasRelatedWork W1970505296 @default.
- W1963399097 hasRelatedWork W1973095062 @default.
- W1963399097 hasRelatedWork W2038512896 @default.
- W1963399097 hasRelatedWork W2039781946 @default.
- W1963399097 hasRelatedWork W2044985824 @default.
- W1963399097 hasRelatedWork W2076974163 @default.
- W1963399097 hasRelatedWork W2107096130 @default.
- W1963399097 hasRelatedWork W2174055414 @default.
- W1963399097 hasVolume "61" @default.
- W1963399097 isParatext "false" @default.
- W1963399097 isRetracted "false" @default.
- W1963399097 magId "1963399097" @default.
- W1963399097 workType "article" @default.