FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963522336> ?p ?o ?g. }

• W1963522336 endingPage "454" @default.
• W1963522336 startingPage "443" @default.
• W1963522336 abstract "Evidence from light microscopy (principally polarization microscopy) has demonstrated that hydrostatic pressure can reversibly inhibit mitosis by rapidly depolymerizing the spindle fiber microtubules. We have confirmed this finding in ultrastructural studies of mitotic HeLa cells incubated at 37 degrees C and pressurized at 680 atm (10,000 psi). Althouth there are many spindle microtubules in the cells at atmospheric pressure, electron micographs of cells pressurized for 10 min (and fixed while under pressure in a Landau-Thibodeau chamber) show few microtubules. Pressure has a differential effect on the various types of spindle microtubules. Astral and interpolar MTs appear to be completely depolymerized in pressurized cells, but occasional groups of kinetochore fiber microtubules are seen. Surprisingly, the length and density of microtubules of the stem bodies and midbody of telophase cells appear unchanged by pressurization. In cells fixed 10 min after pressure was released, microtubules were again abundant, the density often appearing to be higher than in control cells. Reorganization seems incomplete, however, since many of the microtubules are randomly oriented. Unexpectedly, kinetochores appeared diffuse and were difficult to identify in sections of pressurized cells. Even after 10 min of recovery at atmospheric pressure, their structure was less distinct than in unpressurized cells." @default.
• W1963522336 created "2016-06-24" @default.
• W1963522336 creator A5004293034 @default.
• W1963522336 creator A5011106090 @default.
• W1963522336 creator A5078460202 @default.
• W1963522336 creator A5090937089 @default.
• W1963522336 date "1976-05-01" @default.
• W1963522336 modified "2023-09-24" @default.
• W1963522336 title "Pressure-induced depolymerization of spindle microtubules. III. Differential stability in HeLa cells." @default.
• W1963522336 cites W1968130651 @default.
• W1963522336 cites W1971838860 @default.
• W1963522336 cites W1987352006 @default.
• W1963522336 cites W2013995570 @default.
• W1963522336 cites W2014272521 @default.
• W1963522336 cites W2015647287 @default.
• W1963522336 cites W2024264788 @default.
• W1963522336 cites W2027054401 @default.
• W1963522336 cites W2030082883 @default.
• W1963522336 cites W2031926829 @default.
• W1963522336 cites W2032243074 @default.
• W1963522336 cites W2044675881 @default.
• W1963522336 cites W2060205824 @default.
• W1963522336 cites W2063134564 @default.
• W1963522336 cites W2063855981 @default.
• W1963522336 cites W2072737968 @default.
• W1963522336 cites W2075772461 @default.
• W1963522336 cites W2080393723 @default.
• W1963522336 cites W2089817915 @default.
• W1963522336 cites W2104928854 @default.
• W1963522336 cites W2128359402 @default.
• W1963522336 cites W2133553176 @default.
• W1963522336 cites W2137756635 @default.
• W1963522336 cites W2334186748 @default.
• W1963522336 cites W2411515688 @default.
• W1963522336 cites W2419611445 @default.
• W1963522336 cites W2438100971 @default.
• W1963522336 cites W2469424565 @default.
• W1963522336 doi "https://doi.org/10.1083/jcb.69.2.443" @default.
• W1963522336 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2109687" @default.
• W1963522336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1262399" @default.
• W1963522336 hasPublicationYear "1976" @default.
• W1963522336 type Work @default.
• W1963522336 sameAs 1963522336 @default.
• W1963522336 citedByCount "83" @default.
• W1963522336 countsByYear W19635223362012 @default.
• W1963522336 countsByYear W19635223362014 @default.
• W1963522336 countsByYear W19635223362015 @default.
• W1963522336 countsByYear W19635223362016 @default.
• W1963522336 countsByYear W19635223362017 @default.
• W1963522336 countsByYear W19635223362018 @default.
• W1963522336 countsByYear W19635223362019 @default.
• W1963522336 countsByYear W19635223362020 @default.
• W1963522336 countsByYear W19635223362021 @default.
• W1963522336 countsByYear W19635223362022 @default.
• W1963522336 countsByYear W19635223362023 @default.
• W1963522336 crossrefType "journal-article" @default.
• W1963522336 hasAuthorship W1963522336A5004293034 @default.
• W1963522336 hasAuthorship W1963522336A5011106090 @default.
• W1963522336 hasAuthorship W1963522336A5078460202 @default.
• W1963522336 hasAuthorship W1963522336A5090937089 @default.
• W1963522336 hasBestOaLocation W19635223361 @default.
• W1963522336 hasConcept C104317684 @default.
• W1963522336 hasConcept C121332964 @default.
• W1963522336 hasConcept C12554922 @default.
• W1963522336 hasConcept C141561535 @default.
• W1963522336 hasConcept C142669718 @default.
• W1963522336 hasConcept C1491633281 @default.
• W1963522336 hasConcept C192838845 @default.
• W1963522336 hasConcept C20418707 @default.
• W1963522336 hasConcept C2779363559 @default.
• W1963522336 hasConcept C2910081258 @default.
• W1963522336 hasConcept C29537977 @default.
• W1963522336 hasConcept C30481170 @default.
• W1963522336 hasConcept C47432576 @default.
• W1963522336 hasConcept C53420372 @default.
• W1963522336 hasConcept C55493867 @default.
• W1963522336 hasConcept C70278784 @default.
• W1963522336 hasConcept C85813293 @default.
• W1963522336 hasConcept C86803240 @default.
• W1963522336 hasConcept C93304396 @default.
• W1963522336 hasConcept C95444343 @default.
• W1963522336 hasConcept C9565192 @default.
• W1963522336 hasConcept C97355855 @default.
• W1963522336 hasConceptScore W1963522336C104317684 @default.
• W1963522336 hasConceptScore W1963522336C121332964 @default.
• W1963522336 hasConceptScore W1963522336C12554922 @default.
• W1963522336 hasConceptScore W1963522336C141561535 @default.
• W1963522336 hasConceptScore W1963522336C142669718 @default.
• W1963522336 hasConceptScore W1963522336C1491633281 @default.
• W1963522336 hasConceptScore W1963522336C192838845 @default.
• W1963522336 hasConceptScore W1963522336C20418707 @default.
• W1963522336 hasConceptScore W1963522336C2779363559 @default.
• W1963522336 hasConceptScore W1963522336C2910081258 @default.
• W1963522336 hasConceptScore W1963522336C29537977 @default.
• W1963522336 hasConceptScore W1963522336C30481170 @default.
• W1963522336 hasConceptScore W1963522336C47432576 @default.
• W1963522336 hasConceptScore W1963522336C53420372 @default.
• W1963522336 hasConceptScore W1963522336C55493867 @default.

• next