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• W1963523088 abstract "Lung volume changes involve the recruitment of collapsed alveoli and the expansion of already opened alveoli. This study aimed to determine the alveolar recruitment function by using a mathematical model from a pressure-volume curve (P-V curve). We assumed a lung model as VL=R(P)V0f(P), where R recruitment function is the fraction of recruited alveoli, V0 is the resting lung volume at FRC of a fully recruited lung, and f(P) corresponds to the normalized compliance function of the lungs open to ventilation. Seven white rabbits were subjected to saline-lavage lung injury, and P-V curves were calculated using the slow inflation technique. We obtained the P-R curve from the P-V curve, and two curves were differently shaped after lung injury. We concluded that the recruitment function was obtained from the P-V curve and that the P-R curve estimated the recruitment and derecruitment status." @default.
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• W1963523088 date "2015-01-01" @default.
• W1963523088 modified "2023-09-30" @default.
• W1963523088 title "Derivation of recruitment function from the pressure–volume curve in an acute lung injury model" @default.
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• W1963523088 doi "https://doi.org/10.1016/j.resp.2014.09.008" @default.
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