FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963539109> ?p ?o ?g. }

• W1963539109 abstract "Erythrocyte deformation involves both viscous dissipation in the cell interior and viscoelastic motion of the cell membrane. Reports that describe reduced filterability of diabetic erythrocytes, altered response to oscillatory motion in a capillary-sized pipet, and impaired packing during centrifugation indicate a disturbance of red cell rheology in diabetes. We have selected conditions that minimize the macromolecule-mediated energy of attraction between erythrocytes and studied erythrocyte motion during doublet formation. Under such conditions, doublet formation frequency is strikingly reduced in diabetes. For nondiabetic erythrocytes the formation rate is 0.73 doublets per minute, whereas for diabetic erythrocytes the rate is 0.23 doublets per minute. In addition, mean velocity of doublet formation was found to be decreased to half of normal in diabetes. Completeness of doublet formation, regularly diminished when cell size of the two component cells was similar, was the same for diabetic and nondiabetic erythrocytes. Observation of several features of doublet formation gave a picture of the mechanical process. The initial cell making contact with the glass microscope slide was observed to remain fixed in position. The late arriving cell's ability to form a doublet was seen to decrease rapidly, apparently because it came to adhere to the glass surface. The attractive force between the cells overcomes the force of gravity, but cell deformation resistance slows doublet formation by balancing the tendency for cell-cell contact area to increase. An integral equation combining strain energy and viscous dissipation was applied to the doublet formation process. Slowing of doublet formation in diabetes appears to be produced by a doubling of resistance to rate of change of curvature of diabetic erythrocytes." @default.
• W1963539109 created "2016-06-24" @default.
• W1963539109 creator A5001369230 @default.
• W1963539109 creator A5003856707 @default.
• W1963539109 creator A5055230023 @default.
• W1963539109 date "1983-09-01" @default.
• W1963539109 modified "2023-09-26" @default.
• W1963539109 title "Doublet formation of diabetic erythrocytes as a model of impaired membrane viscous deformation" @default.
• W1963539109 cites W1523611615 @default.
• W1963539109 cites W1618719257 @default.
• W1963539109 cites W1970911722 @default.
• W1963539109 cites W1971030972 @default.
• W1963539109 cites W1974671594 @default.
• W1963539109 cites W1979443037 @default.
• W1963539109 cites W1981054060 @default.
• W1963539109 cites W1981135158 @default.
• W1963539109 cites W1990059055 @default.
• W1963539109 cites W1993971815 @default.
• W1963539109 cites W1994244466 @default.
• W1963539109 cites W2001139691 @default.
• W1963539109 cites W2011642892 @default.
• W1963539109 cites W2014157230 @default.
• W1963539109 cites W2030021133 @default.
• W1963539109 cites W2056439226 @default.
• W1963539109 cites W2057673518 @default.
• W1963539109 cites W2067257899 @default.
• W1963539109 cites W2071371060 @default.
• W1963539109 cites W2085831998 @default.
• W1963539109 cites W2090182670 @default.
• W1963539109 cites W2091291019 @default.
• W1963539109 cites W2091819324 @default.
• W1963539109 cites W2092570328 @default.
• W1963539109 cites W2109250419 @default.
• W1963539109 cites W2120155566 @default.
• W1963539109 cites W2125781124 @default.
• W1963539109 cites W2145294053 @default.
• W1963539109 cites W2405138619 @default.
• W1963539109 cites W2405153624 @default.
• W1963539109 cites W2413291161 @default.
• W1963539109 cites W2461110131 @default.
• W1963539109 cites W2798643531 @default.
• W1963539109 cites W2420874076 @default.
• W1963539109 doi "https://doi.org/10.1016/0026-2862(83)90071-7" @default.
• W1963539109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6621409" @default.
• W1963539109 hasPublicationYear "1983" @default.
• W1963539109 type Work @default.
• W1963539109 sameAs 1963539109 @default.
• W1963539109 citedByCount "19" @default.
• W1963539109 countsByYear W19635391092013 @default.
• W1963539109 crossrefType "journal-article" @default.
• W1963539109 hasAuthorship W1963539109A5001369230 @default.
• W1963539109 hasAuthorship W1963539109A5003856707 @default.
• W1963539109 hasAuthorship W1963539109A5055230023 @default.
• W1963539109 hasConcept C121332964 @default.
• W1963539109 hasConcept C12554922 @default.
• W1963539109 hasConcept C135402231 @default.
• W1963539109 hasConcept C159985019 @default.
• W1963539109 hasConcept C185592680 @default.
• W1963539109 hasConcept C186541917 @default.
• W1963539109 hasConcept C192562407 @default.
• W1963539109 hasConcept C204366326 @default.
• W1963539109 hasConcept C2778106830 @default.
• W1963539109 hasConcept C294558 @default.
• W1963539109 hasConcept C41625074 @default.
• W1963539109 hasConcept C43617362 @default.
• W1963539109 hasConcept C55493867 @default.
• W1963539109 hasConcept C57879066 @default.
• W1963539109 hasConcept C7623868 @default.
• W1963539109 hasConcept C86803240 @default.
• W1963539109 hasConcept C97355855 @default.
• W1963539109 hasConceptScore W1963539109C121332964 @default.
• W1963539109 hasConceptScore W1963539109C12554922 @default.
• W1963539109 hasConceptScore W1963539109C135402231 @default.
• W1963539109 hasConceptScore W1963539109C159985019 @default.
• W1963539109 hasConceptScore W1963539109C185592680 @default.
• W1963539109 hasConceptScore W1963539109C186541917 @default.
• W1963539109 hasConceptScore W1963539109C192562407 @default.
• W1963539109 hasConceptScore W1963539109C204366326 @default.
• W1963539109 hasConceptScore W1963539109C2778106830 @default.
• W1963539109 hasConceptScore W1963539109C294558 @default.
• W1963539109 hasConceptScore W1963539109C41625074 @default.
• W1963539109 hasConceptScore W1963539109C43617362 @default.
• W1963539109 hasConceptScore W1963539109C55493867 @default.
• W1963539109 hasConceptScore W1963539109C57879066 @default.
• W1963539109 hasConceptScore W1963539109C7623868 @default.
• W1963539109 hasConceptScore W1963539109C86803240 @default.
• W1963539109 hasConceptScore W1963539109C97355855 @default.
• W1963539109 hasLocation W19635391091 @default.
• W1963539109 hasLocation W19635391092 @default.
• W1963539109 hasOpenAccess W1963539109 @default.
• W1963539109 hasPrimaryLocation W19635391091 @default.
• W1963539109 hasRelatedWork W100046603 @default.
• W1963539109 hasRelatedWork W1562825120 @default.
• W1963539109 hasRelatedWork W2032161274 @default.
• W1963539109 hasRelatedWork W2050932217 @default.
• W1963539109 hasRelatedWork W2068706248 @default.
• W1963539109 hasRelatedWork W2069222261 @default.
• W1963539109 hasRelatedWork W2078537913 @default.
• W1963539109 hasRelatedWork W2319612038 @default.
• W1963539109 hasRelatedWork W4285600993 @default.

• next