FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963540950> ?p ?o ?g. }

• W1963540950 endingPage "641" @default.
• W1963540950 startingPage "631" @default.
• W1963540950 abstract "5'-AMP-activated protein kinase (AMPK) has been proposed to be a pivotal factor in cellular responses to both acute exercise and exercise training. To investigate whether protein levels and gene expression of catalytic (alpha(1), alpha(2)) and regulatory (beta(1), beta(2), gamma(1), gamma(2), gamma(3)) AMPK subunits and exercise-induced AMPK activity are influenced by exercise training status, muscle biopsies were obtained from seven endurance exercise-trained and seven sedentary young healthy men. The alpha(1)- and alpha(2)-AMPK mRNA contents in trained subjects were both 117 +/- 2% of that in sedentary subjects (not significant), whereas mRNA for gamma(3) was 61 +/- 1% of that in sedentary subjects (not significant). The level of alpha(1)-AMPK protein in trained subjects was 185 +/- 34% of that in sedentary subjects (P < 0.05), whereas the levels of the remaining subunits (alpha(2), beta(1), beta(2), gamma(1), gamma(2), gamma(3)) were similar in trained and sedentary subjects. At the end of 20 min of cycle exercise at 80% of peak O(2) uptake, the increase in phosphorylation of alpha-AMPK (Thr(172)) was blunted in the trained group (138 +/- 38% above rest) compared with the sedentary group (353 +/- 63% above rest) (P < 0.05). Acetyl CoA-carboxylase beta-phosphorylation (Ser(221)), which is a marker for in vivo AMPK activity, was increased by exercise in both groups but to a lower level in trained subjects (32 +/- 5 arbitrary units) than in sedentary controls (45 +/- 1 arbitrary units) (P < 0.01). In conclusion, trained human skeletal muscle has increased alpha(1)-AMPK protein levels and blunted AMPK activation during exercise." @default.
• W1963540950 created "2016-06-24" @default.
• W1963540950 creator A5004718751 @default.
• W1963540950 creator A5012534532 @default.
• W1963540950 creator A5018204703 @default.
• W1963540950 creator A5026726271 @default.
• W1963540950 creator A5039041871 @default.
• W1963540950 creator A5039947894 @default.
• W1963540950 creator A5046976143 @default.
• W1963540950 creator A5078266572 @default.
• W1963540950 creator A5081712454 @default.
• W1963540950 creator A5082849658 @default.
• W1963540950 date "2003-02-01" @default.
• W1963540950 modified "2023-10-12" @default.
• W1963540950 title "5′-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle" @default.
• W1963540950 cites W1582646265 @default.
• W1963540950 cites W1820085648 @default.
• W1963540950 cites W1862549530 @default.
• W1963540950 cites W1876043561 @default.
• W1963540950 cites W1880875467 @default.
• W1963540950 cites W1959374451 @default.
• W1963540950 cites W1972762474 @default.
• W1963540950 cites W1973749169 @default.
• W1963540950 cites W1974669825 @default.
• W1963540950 cites W1978299773 @default.
• W1963540950 cites W1978679812 @default.
• W1963540950 cites W1978763812 @default.
• W1963540950 cites W1983834588 @default.
• W1963540950 cites W1986503768 @default.
• W1963540950 cites W1988243311 @default.
• W1963540950 cites W1994010459 @default.
• W1963540950 cites W2030636484 @default.
• W1963540950 cites W2041884974 @default.
• W1963540950 cites W2043468864 @default.
• W1963540950 cites W2050689899 @default.
• W1963540950 cites W2067522487 @default.
• W1963540950 cites W2069811002 @default.
• W1963540950 cites W2075496544 @default.
• W1963540950 cites W2083655799 @default.
• W1963540950 cites W2105880387 @default.
• W1963540950 cites W2128895419 @default.
• W1963540950 cites W2129989499 @default.
• W1963540950 cites W2131501155 @default.
• W1963540950 cites W2133201298 @default.
• W1963540950 cites W2134535786 @default.
• W1963540950 cites W2140558936 @default.
• W1963540950 cites W2143423943 @default.
• W1963540950 cites W2144417251 @default.
• W1963540950 cites W2145257045 @default.
• W1963540950 cites W2156516623 @default.
• W1963540950 cites W2156518233 @default.
• W1963540950 cites W2159816315 @default.
• W1963540950 cites W2165796742 @default.
• W1963540950 cites W2170880090 @default.
• W1963540950 cites W2172189555 @default.
• W1963540950 cites W2172299004 @default.
• W1963540950 cites W2176414067 @default.
• W1963540950 cites W2183833173 @default.
• W1963540950 cites W2184995059 @default.
• W1963540950 cites W2252715661 @default.
• W1963540950 cites W2263689279 @default.
• W1963540950 cites W2288476581 @default.
• W1963540950 cites W2294037282 @default.
• W1963540950 cites W2298277015 @default.
• W1963540950 cites W2328294727 @default.
• W1963540950 cites W2467696136 @default.
• W1963540950 cites W29771769 @default.
• W1963540950 cites W323133370 @default.
• W1963540950 cites W4235264311 @default.
• W1963540950 cites W4245375724 @default.
• W1963540950 cites W4253396598 @default.
• W1963540950 cites W4294216491 @default.
• W1963540950 doi "https://doi.org/10.1152/japplphysiol.00642.2002" @default.
• W1963540950 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12391032" @default.
• W1963540950 hasPublicationYear "2003" @default.
• W1963540950 type Work @default.
• W1963540950 sameAs 1963540950 @default.
• W1963540950 citedByCount "140" @default.
• W1963540950 countsByYear W19635409502012 @default.
• W1963540950 countsByYear W19635409502013 @default.
• W1963540950 countsByYear W19635409502014 @default.
• W1963540950 countsByYear W19635409502015 @default.
• W1963540950 countsByYear W19635409502016 @default.
• W1963540950 countsByYear W19635409502017 @default.
• W1963540950 countsByYear W19635409502018 @default.
• W1963540950 countsByYear W19635409502019 @default.
• W1963540950 countsByYear W19635409502020 @default.
• W1963540950 countsByYear W19635409502021 @default.
• W1963540950 countsByYear W19635409502022 @default.
• W1963540950 countsByYear W19635409502023 @default.
• W1963540950 crossrefType "journal-article" @default.
• W1963540950 hasAuthorship W1963540950A5004718751 @default.
• W1963540950 hasAuthorship W1963540950A5012534532 @default.
• W1963540950 hasAuthorship W1963540950A5018204703 @default.
• W1963540950 hasAuthorship W1963540950A5026726271 @default.
• W1963540950 hasAuthorship W1963540950A5039041871 @default.
• W1963540950 hasAuthorship W1963540950A5039947894 @default.
• W1963540950 hasAuthorship W1963540950A5046976143 @default.

• next