Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963548841> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1963548841 endingPage "366" @default.
- W1963548841 startingPage "359" @default.
- W1963548841 abstract "Metabolism of glutamate and glutamine in cultured mouse cerebral cortical astrocytes has been investigated using either radioactively labelled (14C) amino acids or 13C-labelled amino acids combined with NMR spectroscopy of cell extracts and lyophilyzed incubation media. Using [U-13C]glutamate it has been shown that in astrocytes exogenously supplied glutamate is primarily (70%) metabolized oxidatively through the tricarboxylic acid (TCA) cycle and to a lesser extent (30%) directly to glutamine. Glutamate metabolized in the TCA cycle is to a large extent recovered as lactate showing that the astrocyte-specific enzyme, malic enzyme is functionally active. Incubation with [U-14C]glutamine led to a higher specific radioactivity in glutamate than in glutamine. It could also be shown that glutamate and glutamine were metabolized differently to aspartate and alanine. These results taken together strongly suggest that glutamate/glutamine metabolism in astrocytes is compartmentalized and a model with multiple cytoplasmic and mitochondrial compartments of these amino acids is proposed." @default.
- W1963548841 created "2016-06-24" @default.
- W1963548841 creator A5032591483 @default.
- W1963548841 creator A5041695818 @default.
- W1963548841 creator A5055789216 @default.
- W1963548841 creator A5055872212 @default.
- W1963548841 creator A5060434388 @default.
- W1963548841 creator A5061796601 @default.
- W1963548841 creator A5080615404 @default.
- W1963548841 date "1993-01-01" @default.
- W1963548841 modified "2023-09-25" @default.
- W1963548841 title "Glutamate and Glutamine Metabolism and Compartmentation in Astrocytes" @default.
- W1963548841 doi "https://doi.org/10.1159/000111356" @default.
- W1963548841 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7805590" @default.
- W1963548841 hasPublicationYear "1993" @default.
- W1963548841 type Work @default.
- W1963548841 sameAs 1963548841 @default.
- W1963548841 citedByCount "158" @default.
- W1963548841 countsByYear W19635488412012 @default.
- W1963548841 countsByYear W19635488412013 @default.
- W1963548841 countsByYear W19635488412014 @default.
- W1963548841 countsByYear W19635488412015 @default.
- W1963548841 countsByYear W19635488412016 @default.
- W1963548841 countsByYear W19635488412017 @default.
- W1963548841 countsByYear W19635488412018 @default.
- W1963548841 countsByYear W19635488412019 @default.
- W1963548841 countsByYear W19635488412021 @default.
- W1963548841 countsByYear W19635488412022 @default.
- W1963548841 countsByYear W19635488412023 @default.
- W1963548841 crossrefType "journal-article" @default.
- W1963548841 hasAuthorship W1963548841A5032591483 @default.
- W1963548841 hasAuthorship W1963548841A5041695818 @default.
- W1963548841 hasAuthorship W1963548841A5055789216 @default.
- W1963548841 hasAuthorship W1963548841A5055872212 @default.
- W1963548841 hasAuthorship W1963548841A5060434388 @default.
- W1963548841 hasAuthorship W1963548841A5061796601 @default.
- W1963548841 hasAuthorship W1963548841A5080615404 @default.
- W1963548841 hasConcept C134018914 @default.
- W1963548841 hasConcept C156310829 @default.
- W1963548841 hasConcept C165135838 @default.
- W1963548841 hasConcept C170493617 @default.
- W1963548841 hasConcept C2776441662 @default.
- W1963548841 hasConcept C2777202666 @default.
- W1963548841 hasConcept C2777542381 @default.
- W1963548841 hasConcept C2778740566 @default.
- W1963548841 hasConcept C2779289688 @default.
- W1963548841 hasConcept C2779349466 @default.
- W1963548841 hasConcept C2779856020 @default.
- W1963548841 hasConcept C49051014 @default.
- W1963548841 hasConcept C515207424 @default.
- W1963548841 hasConcept C529278444 @default.
- W1963548841 hasConcept C55493867 @default.
- W1963548841 hasConcept C61174792 @default.
- W1963548841 hasConcept C62231903 @default.
- W1963548841 hasConcept C86803240 @default.
- W1963548841 hasConceptScore W1963548841C134018914 @default.
- W1963548841 hasConceptScore W1963548841C156310829 @default.
- W1963548841 hasConceptScore W1963548841C165135838 @default.
- W1963548841 hasConceptScore W1963548841C170493617 @default.
- W1963548841 hasConceptScore W1963548841C2776441662 @default.
- W1963548841 hasConceptScore W1963548841C2777202666 @default.
- W1963548841 hasConceptScore W1963548841C2777542381 @default.
- W1963548841 hasConceptScore W1963548841C2778740566 @default.
- W1963548841 hasConceptScore W1963548841C2779289688 @default.
- W1963548841 hasConceptScore W1963548841C2779349466 @default.
- W1963548841 hasConceptScore W1963548841C2779856020 @default.
- W1963548841 hasConceptScore W1963548841C49051014 @default.
- W1963548841 hasConceptScore W1963548841C515207424 @default.
- W1963548841 hasConceptScore W1963548841C529278444 @default.
- W1963548841 hasConceptScore W1963548841C55493867 @default.
- W1963548841 hasConceptScore W1963548841C61174792 @default.
- W1963548841 hasConceptScore W1963548841C62231903 @default.
- W1963548841 hasConceptScore W1963548841C86803240 @default.
- W1963548841 hasIssue "3-5" @default.
- W1963548841 hasLocation W19635488411 @default.
- W1963548841 hasLocation W19635488412 @default.
- W1963548841 hasOpenAccess W1963548841 @default.
- W1963548841 hasPrimaryLocation W19635488411 @default.
- W1963548841 hasRelatedWork W1963548841 @default.
- W1963548841 hasRelatedWork W1970217675 @default.
- W1963548841 hasRelatedWork W1978607655 @default.
- W1963548841 hasRelatedWork W1988929832 @default.
- W1963548841 hasRelatedWork W2002802452 @default.
- W1963548841 hasRelatedWork W2016763790 @default.
- W1963548841 hasRelatedWork W2022188529 @default.
- W1963548841 hasRelatedWork W2123715446 @default.
- W1963548841 hasRelatedWork W2169054484 @default.
- W1963548841 hasRelatedWork W4249626140 @default.
- W1963548841 hasVolume "15" @default.
- W1963548841 isParatext "false" @default.
- W1963548841 isRetracted "false" @default.
- W1963548841 magId "1963548841" @default.
- W1963548841 workType "article" @default.