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- W1963556560 endingPage "280" @default.
- W1963556560 startingPage "265" @default.
- W1963556560 abstract "Continuous endothelium and epithelium create formidable barriers to endogenous molecules as well as targeted drug and gene therapies in vivo. Caveolae represent a possible vesicular trafficking pathway through cell barriers. Here we discuss recent discoveries regarding the basic function of caveolae in transport including transcellular trafficking, intracellular trafficking to distinct endosomes, and molecular mechanisms mediating their budding, docking and fusion (dynamin and SNARE machinery). New technologies to purify and map caveolae as well as generate new probes selectively targeting caveolae in vivo provide valuable tools not only for investigating caveolar endocytosis/transcytosis but also elucidating new potential applications for site-directed treatment of many diseases. Vascular targeting of the caveolar trafficking pathway may be a useful strategy for achieving tissue-specific pharmacodelivery that also overcomes key, normally restrictive cell barriers which greatly reduce the efficacy of many therapies in vivo." @default.
- W1963556560 created "2016-06-24" @default.
- W1963556560 creator A5088179368 @default.
- W1963556560 date "2001-07-01" @default.
- W1963556560 modified "2023-10-01" @default.
- W1963556560 title "Caveolae: from basic trafficking mechanisms to targeting transcytosis for tissue-specific drug and gene delivery in vivo" @default.
- W1963556560 cites W1500322150 @default.
- W1963556560 cites W1509564548 @default.
- W1963556560 cites W1557964895 @default.
- W1963556560 cites W1575436886 @default.
- W1963556560 cites W1575798288 @default.
- W1963556560 cites W1576261436 @default.
- W1963556560 cites W1639884599 @default.
- W1963556560 cites W1844290320 @default.
- W1963556560 cites W1913982549 @default.
- W1963556560 cites W1965018133 @default.
- W1963556560 cites W1974043466 @default.
- W1963556560 cites W1975572503 @default.
- W1963556560 cites W1976556281 @default.
- W1963556560 cites W1980773456 @default.
- W1963556560 cites W1980776868 @default.
- W1963556560 cites W1980857768 @default.
- W1963556560 cites W1983915199 @default.
- W1963556560 cites W1985599453 @default.
- W1963556560 cites W1986812906 @default.
- W1963556560 cites W1987967672 @default.
- W1963556560 cites W1995150314 @default.
- W1963556560 cites W1995348524 @default.
- W1963556560 cites W1996219643 @default.
- W1963556560 cites W1996845777 @default.
- W1963556560 cites W1997702964 @default.
- W1963556560 cites W1997726565 @default.
- W1963556560 cites W1997760135 @default.
- W1963556560 cites W2000764878 @default.
- W1963556560 cites W2003461672 @default.
- W1963556560 cites W2005873851 @default.
- W1963556560 cites W2008455568 @default.
- W1963556560 cites W2009328749 @default.
- W1963556560 cites W2024511394 @default.
- W1963556560 cites W2029255946 @default.
- W1963556560 cites W2029265259 @default.
- W1963556560 cites W2029325023 @default.
- W1963556560 cites W2029623118 @default.
- W1963556560 cites W2029634948 @default.
- W1963556560 cites W2030824268 @default.
- W1963556560 cites W2032546204 @default.
- W1963556560 cites W2036477188 @default.
- W1963556560 cites W2040945595 @default.
- W1963556560 cites W2044201289 @default.
- W1963556560 cites W2049215266 @default.
- W1963556560 cites W2049294834 @default.
- W1963556560 cites W2050465028 @default.
- W1963556560 cites W2057724921 @default.
- W1963556560 cites W2059401279 @default.
- W1963556560 cites W2060593058 @default.
- W1963556560 cites W2062109496 @default.
- W1963556560 cites W2068800887 @default.
- W1963556560 cites W2069444054 @default.
- W1963556560 cites W2071151029 @default.
- W1963556560 cites W2071738676 @default.
- W1963556560 cites W2072251236 @default.
- W1963556560 cites W2072936656 @default.
- W1963556560 cites W2074753255 @default.
- W1963556560 cites W2076185826 @default.
- W1963556560 cites W2076315214 @default.
- W1963556560 cites W2079453469 @default.
- W1963556560 cites W2081513562 @default.
- W1963556560 cites W2084957832 @default.
- W1963556560 cites W2085145451 @default.
- W1963556560 cites W2086199657 @default.
- W1963556560 cites W2087259588 @default.
- W1963556560 cites W2087896363 @default.
- W1963556560 cites W2088638510 @default.
- W1963556560 cites W2089333920 @default.
- W1963556560 cites W2091707906 @default.
- W1963556560 cites W2091806370 @default.
- W1963556560 cites W2110305967 @default.
- W1963556560 cites W2112465136 @default.
- W1963556560 cites W2114356820 @default.
- W1963556560 cites W2117468682 @default.
- W1963556560 cites W2124900990 @default.
- W1963556560 cites W2145247599 @default.
- W1963556560 cites W2150846836 @default.
- W1963556560 cites W2153689647 @default.
- W1963556560 cites W2157773619 @default.
- W1963556560 cites W2161484620 @default.
- W1963556560 cites W2171545812 @default.
- W1963556560 cites W2188775934 @default.
- W1963556560 cites W23774700 @default.
- W1963556560 cites W2415442654 @default.
- W1963556560 cites W4231136244 @default.
- W1963556560 cites W4239088562 @default.
- W1963556560 doi "https://doi.org/10.1016/s0169-409x(01)00141-7" @default.
- W1963556560 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11551399" @default.
- W1963556560 hasPublicationYear "2001" @default.
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