FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963566235> ?p ?o ?g. }

• W1963566235 endingPage "931" @default.
• W1963566235 startingPage "926" @default.
• W1963566235 abstract "YKL-40 (cartilage gp-39), is a mammalian glycoprotein related in sequence to chitinases. Its function is unknown, but it is thought to be involved in tissue remodeling. Immunocytochemical staining of YKL-40 in guinea pig chondrocytes (GPC), rabbit chondrocytes (RC), and rabbit synoviocytes (RS) was higher in dividing cells than in confluent cells, suggesting a participation of YKL-40 in cell cycle events. As assessed by the MTT assay, YKL-40 at 1.9–7.6 nM had dose-dependent mitogenic activity toward the three cell types. At 7.6 nM, YKL-40 increased the number of cells of 42% in GPC, 75% in RC, and 86% in RS after 72 h. YKL-40 also stimulated total proteoglycan synthesis by chondrocytes in a dose-dependent manner as assessed by Na[35SO4] incorporation and cetylpyridinium chloride precipitation. At 9.4 nM, YKL-40 increased proteoglycan synthesis of 42% in GPC and 58% in RC after 24 h. The growth factor properties of YKL-40 may explain the increased tissue remodeling associated with high levels of YKL-40 in joint diseases, and possibly, in malignant pathologies such as breast cancer or colorectal cancer." @default.
• W1963566235 created "2016-06-24" @default.
• W1963566235 creator A5002524602 @default.
• W1963566235 creator A5006056279 @default.
• W1963566235 creator A5033112937 @default.
• W1963566235 creator A5034274888 @default.
• W1963566235 creator A5034622975 @default.
• W1963566235 creator A5034651734 @default.
• W1963566235 date "2001-07-01" @default.
• W1963566235 modified "2023-10-09" @default.
• W1963566235 title "YKL-40 (Cartilage gp-39) Induces Proliferative Events in Cultured Chondrocytes and Synoviocytes and Increases Glycosaminoglycan Synthesis in Chondrocytes" @default.
• W1963566235 cites W1568609804 @default.
• W1963566235 cites W1629179716 @default.
• W1963566235 cites W1772341111 @default.
• W1963566235 cites W1985751498 @default.
• W1963566235 cites W2009381153 @default.
• W1963566235 cites W2011543866 @default.
• W1963566235 cites W2011875625 @default.
• W1963566235 cites W2033092310 @default.
• W1963566235 cites W2043610475 @default.
• W1963566235 cites W2043750179 @default.
• W1963566235 cites W2044162047 @default.
• W1963566235 cites W2046609279 @default.
• W1963566235 cites W2049079346 @default.
• W1963566235 cites W2052870595 @default.
• W1963566235 cites W2058365984 @default.
• W1963566235 cites W2060851093 @default.
• W1963566235 cites W2064523705 @default.
• W1963566235 cites W2072370768 @default.
• W1963566235 cites W2077406869 @default.
• W1963566235 cites W2100571347 @default.
• W1963566235 cites W2129674644 @default.
• W1963566235 cites W2133628830 @default.
• W1963566235 cites W2137625026 @default.
• W1963566235 cites W2137961859 @default.
• W1963566235 cites W2149162014 @default.
• W1963566235 cites W2168857929 @default.
• W1963566235 cites W261597661 @default.
• W1963566235 doi "https://doi.org/10.1006/bbrc.2001.5253" @default.
• W1963566235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11467840" @default.
• W1963566235 hasPublicationYear "2001" @default.
• W1963566235 type Work @default.
• W1963566235 sameAs 1963566235 @default.
• W1963566235 citedByCount "169" @default.
• W1963566235 countsByYear W19635662352012 @default.
• W1963566235 countsByYear W19635662352013 @default.
• W1963566235 countsByYear W19635662352014 @default.
• W1963566235 countsByYear W19635662352015 @default.
• W1963566235 countsByYear W19635662352016 @default.
• W1963566235 countsByYear W19635662352017 @default.
• W1963566235 countsByYear W19635662352018 @default.
• W1963566235 countsByYear W19635662352019 @default.
• W1963566235 countsByYear W19635662352020 @default.
• W1963566235 countsByYear W19635662352021 @default.
• W1963566235 countsByYear W19635662352022 @default.
• W1963566235 countsByYear W19635662352023 @default.
• W1963566235 crossrefType "journal-article" @default.
• W1963566235 hasAuthorship W1963566235A5002524602 @default.
• W1963566235 hasAuthorship W1963566235A5006056279 @default.
• W1963566235 hasAuthorship W1963566235A5033112937 @default.
• W1963566235 hasAuthorship W1963566235A5034274888 @default.
• W1963566235 hasAuthorship W1963566235A5034622975 @default.
• W1963566235 hasAuthorship W1963566235A5034651734 @default.
• W1963566235 hasConcept C105702510 @default.
• W1963566235 hasConcept C134018914 @default.
• W1963566235 hasConcept C142724271 @default.
• W1963566235 hasConcept C153074725 @default.
• W1963566235 hasConcept C153911025 @default.
• W1963566235 hasConcept C185592680 @default.
• W1963566235 hasConcept C189165786 @default.
• W1963566235 hasConcept C197534660 @default.
• W1963566235 hasConcept C204787440 @default.
• W1963566235 hasConcept C2776164576 @default.
• W1963566235 hasConcept C2779335624 @default.
• W1963566235 hasConcept C2780550940 @default.
• W1963566235 hasConcept C2780804394 @default.
• W1963566235 hasConcept C3020332539 @default.
• W1963566235 hasConcept C55493867 @default.
• W1963566235 hasConcept C71924100 @default.
• W1963566235 hasConcept C86803240 @default.
• W1963566235 hasConcept C95444343 @default.
• W1963566235 hasConceptScore W1963566235C105702510 @default.
• W1963566235 hasConceptScore W1963566235C134018914 @default.
• W1963566235 hasConceptScore W1963566235C142724271 @default.
• W1963566235 hasConceptScore W1963566235C153074725 @default.
• W1963566235 hasConceptScore W1963566235C153911025 @default.
• W1963566235 hasConceptScore W1963566235C185592680 @default.
• W1963566235 hasConceptScore W1963566235C189165786 @default.
• W1963566235 hasConceptScore W1963566235C197534660 @default.
• W1963566235 hasConceptScore W1963566235C204787440 @default.
• W1963566235 hasConceptScore W1963566235C2776164576 @default.
• W1963566235 hasConceptScore W1963566235C2779335624 @default.
• W1963566235 hasConceptScore W1963566235C2780550940 @default.
• W1963566235 hasConceptScore W1963566235C2780804394 @default.
• W1963566235 hasConceptScore W1963566235C3020332539 @default.
• W1963566235 hasConceptScore W1963566235C55493867 @default.
• W1963566235 hasConceptScore W1963566235C71924100 @default.
• W1963566235 hasConceptScore W1963566235C86803240 @default.

• next