FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963575520> ?p ?o ?g. }

• W1963575520 endingPage "72" @default.
• W1963575520 startingPage "68" @default.
• W1963575520 abstract "Liver transplant recipients requiring dialysis have poor outcomes including higher risk of infection, and allograft rejection. The role of T-helper cell cytokine responses in the pathogenesis of infections in these patients has not been fully defined. Cases were 11 dialyzed liver transplant recipients. Controls (2 for each case) were patients who were transplanted next to the case but did not require dialysis at any time before or after transplantation. Cytokine responses were assessed in sera collected immediately before transplantation. Data were analyzed for candidate cytokines for pro-inflammatory Th1 (IL-1β, IL-12p70, and IFN-γ), and Th17 (IL-12p40, IL-17), and anti-inflammatory Th2 phenotypes (IL-4, IL-5, IL-10, and IL-13). Cases were more likely to have an increase in any of the Th1 or Th1 and Th17 cytokines than the controls (p = 0.016 and p = 0.04, respectively). Major infections developed in 27% of the study population; these included 46% of the cases and18%, of the controls (p = 0.09). Patients with infections vs. those without these were more likely to have an increase in any of the Th2 cytokines (p = 0.005). CMV viremia occurred in 30% of the patients and was significantly associated with Th1 responses even when adjusted for CMV recipient/donor serostatus or any major infection (OR 3.2, 95% CI 0.96–10.73, p = 0.05). Requirement of dialysis was characterized by a state of heightened expression of inflammatory responses. However, patients developing infections preferentially expressed Th2 phenotype that may act as a negative regulator of protective inflammatory responses. An enhanced expression of inflammatory mediators may serve to promote CMV infection in liver transplant recipients." @default.
• W1963575520 created "2016-06-24" @default.
• W1963575520 creator A5020920868 @default.
• W1963575520 creator A5036514788 @default.
• W1963575520 creator A5047717026 @default.
• W1963575520 creator A5079624082 @default.
• W1963575520 creator A5088731422 @default.
• W1963575520 creator A5091669686 @default.
• W1963575520 date "2008-11-01" @default.
• W1963575520 modified "2023-10-16" @default.
• W1963575520 title "Dysregulated expression of T-helper cell responses and susceptibility to infections in high-risk liver transplant recipients" @default.
• W1963575520 cites W1527011538 @default.
• W1963575520 cites W1539406292 @default.
• W1963575520 cites W1549542172 @default.
• W1963575520 cites W1566992315 @default.
• W1963575520 cites W1909710500 @default.
• W1963575520 cites W193881150 @default.
• W1963575520 cites W1942668068 @default.
• W1963575520 cites W1963835797 @default.
• W1963575520 cites W1965917942 @default.
• W1963575520 cites W1967337145 @default.
• W1963575520 cites W1972602524 @default.
• W1963575520 cites W1973600141 @default.
• W1963575520 cites W1983737882 @default.
• W1963575520 cites W1984665530 @default.
• W1963575520 cites W1984847643 @default.
• W1963575520 cites W1985729894 @default.
• W1963575520 cites W1986655901 @default.
• W1963575520 cites W1999002546 @default.
• W1963575520 cites W2003511993 @default.
• W1963575520 cites W2007240987 @default.
• W1963575520 cites W2016617351 @default.
• W1963575520 cites W2042515335 @default.
• W1963575520 cites W2051510586 @default.
• W1963575520 cites W2057842409 @default.
• W1963575520 cites W2060947665 @default.
• W1963575520 cites W2064835506 @default.
• W1963575520 cites W2065419883 @default.
• W1963575520 cites W2067937110 @default.
• W1963575520 cites W2071294349 @default.
• W1963575520 cites W2073060575 @default.
• W1963575520 cites W2074398469 @default.
• W1963575520 cites W2085210988 @default.
• W1963575520 cites W2086571444 @default.
• W1963575520 cites W2091391812 @default.
• W1963575520 cites W2101683974 @default.
• W1963575520 cites W2106530602 @default.
• W1963575520 cites W2112866067 @default.
• W1963575520 cites W2140436032 @default.
• W1963575520 cites W2154514239 @default.
• W1963575520 cites W2154759334 @default.
• W1963575520 cites W2161074777 @default.
• W1963575520 cites W2165804863 @default.
• W1963575520 cites W2776663677 @default.
• W1963575520 doi "https://doi.org/10.1016/j.trim.2008.08.001" @default.
• W1963575520 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18761089" @default.
• W1963575520 hasPublicationYear "2008" @default.
• W1963575520 type Work @default.
• W1963575520 sameAs 1963575520 @default.
• W1963575520 citedByCount "12" @default.
• W1963575520 countsByYear W19635755202012 @default.
• W1963575520 countsByYear W19635755202013 @default.
• W1963575520 countsByYear W19635755202015 @default.
• W1963575520 countsByYear W19635755202016 @default.
• W1963575520 countsByYear W19635755202021 @default.
• W1963575520 countsByYear W19635755202023 @default.
• W1963575520 crossrefType "journal-article" @default.
• W1963575520 hasAuthorship W1963575520A5020920868 @default.
• W1963575520 hasAuthorship W1963575520A5036514788 @default.
• W1963575520 hasAuthorship W1963575520A5047717026 @default.
• W1963575520 hasAuthorship W1963575520A5079624082 @default.
• W1963575520 hasAuthorship W1963575520A5088731422 @default.
• W1963575520 hasAuthorship W1963575520A5091669686 @default.
• W1963575520 hasConcept C126322002 @default.
• W1963575520 hasConcept C142462285 @default.
• W1963575520 hasConcept C159654299 @default.
• W1963575520 hasConcept C203014093 @default.
• W1963575520 hasConcept C2522874641 @default.
• W1963575520 hasConcept C2776090121 @default.
• W1963575520 hasConcept C2776185481 @default.
• W1963575520 hasConcept C2776535787 @default.
• W1963575520 hasConcept C2778690821 @default.
• W1963575520 hasConcept C2779978075 @default.
• W1963575520 hasConcept C2780942790 @default.
• W1963575520 hasConcept C2781136212 @default.
• W1963575520 hasConcept C2908647359 @default.
• W1963575520 hasConcept C2911091166 @default.
• W1963575520 hasConcept C71924100 @default.
• W1963575520 hasConcept C8891405 @default.
• W1963575520 hasConcept C99454951 @default.
• W1963575520 hasConceptScore W1963575520C126322002 @default.
• W1963575520 hasConceptScore W1963575520C142462285 @default.
• W1963575520 hasConceptScore W1963575520C159654299 @default.
• W1963575520 hasConceptScore W1963575520C203014093 @default.
• W1963575520 hasConceptScore W1963575520C2522874641 @default.
• W1963575520 hasConceptScore W1963575520C2776090121 @default.
• W1963575520 hasConceptScore W1963575520C2776185481 @default.
• W1963575520 hasConceptScore W1963575520C2776535787 @default.

• next