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- W1963579541 abstract "Although coronaviruses are known to infect various animals by adapting to new hosts, interspecies transmission events are still poorly understood. During a surveillance study from 2005 to 2010, a novel alphacoronavirus, BatCoV HKU10, was detected in two very different bat species, Ro-BatCoV HKU10 in Leschenault's rousettes (Rousettus leschenaulti) (fruit bats in the suborder Megachiroptera) in Guangdong and Hi-BatCoV HKU10 in Pomona leaf-nosed bats (Hipposideros pomona) (insectivorous bats in the suborder Microchiroptera) in Hong Kong. Although infected bats appeared to be healthy, Pomona leaf-nosed bats carrying Hi-BatCoV HKU10 had lower body weights than uninfected bats. To investigate possible interspecies transmission between the two bat species, the complete genomes of two Ro-BatCoV HKU10 and six Hi-BatCoV HKU10 strains were sequenced. Genome and phylogenetic analyses showed that Ro-BatCoV HKU10 and Hi-BatCoV HKU10 represented a novel alphacoronavirus species, sharing highly similar genomes except in the genes encoding spike proteins, which had only 60.5% amino acid identities. Evolution of the spike protein was also rapid in Hi-BatCoV HKU10 strains from 2005 to 2006 but stabilized thereafter. Molecular-clock analysis dated the most recent common ancestor of all BatCoV HKU10 strains to 1959 (highest posterior density regions at 95% [HPDs], 1886 to 2002) and that of Hi-BatCoV HKU10 to 1986 (HPDs, 1956 to 2004). The data suggested recent interspecies transmission from Leschenault's rousettes to Pomona leaf-nosed bats in southern China. Notably, the rapid adaptive genetic change in BatCoV HKU10 spike protein by ~40% amino acid divergence after recent interspecies transmission was even greater than the ~20% amino acid divergence between spike proteins of severe acute respiratory syndrome-related Rhinolophus bat coronavirus (SARSr-CoV) in bats and civets. This study provided the first evidence for interspecies transmission of coronavirus between bats of different suborders." @default.
- W1963579541 created "2016-06-24" @default.
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- W1963579541 date "2012-11-01" @default.
- W1963579541 modified "2023-10-06" @default.
- W1963579541 title "Recent Transmission of a Novel Alphacoronavirus, Bat Coronavirus HKU10, from Leschenault's Rousettes to Pomona Leaf-Nosed Bats: First Evidence of Interspecies Transmission of Coronavirus between Bats of Different Suborders" @default.
- W1963579541 cites W1551068445 @default.
- W1963579541 cites W1811783050 @default.
- W1963579541 cites W1937553338 @default.
- W1963579541 cites W1965435260 @default.
- W1963579541 cites W1966238900 @default.
- W1963579541 cites W1971578982 @default.
- W1963579541 cites W1975520452 @default.
- W1963579541 cites W1979615660 @default.
- W1963579541 cites W1980517850 @default.
- W1963579541 cites W1982005006 @default.
- W1963579541 cites W1982754464 @default.
- W1963579541 cites W1990059132 @default.
- W1963579541 cites W1993964516 @default.
- W1963579541 cites W2001871525 @default.
- W1963579541 cites W2002349004 @default.
- W1963579541 cites W2015213940 @default.
- W1963579541 cites W2025170735 @default.
- W1963579541 cites W2027518730 @default.
- W1963579541 cites W2029947080 @default.
- W1963579541 cites W2034740482 @default.
- W1963579541 cites W2036144053 @default.
- W1963579541 cites W2038918691 @default.
- W1963579541 cites W2046153984 @default.
- W1963579541 cites W2051101821 @default.
- W1963579541 cites W2055012634 @default.
- W1963579541 cites W2060809301 @default.
- W1963579541 cites W2065904254 @default.
- W1963579541 cites W2068921257 @default.
- W1963579541 cites W2069059657 @default.
- W1963579541 cites W2069831575 @default.
- W1963579541 cites W2078917493 @default.
- W1963579541 cites W2083083882 @default.
- W1963579541 cites W2094206246 @default.
- W1963579541 cites W2099731870 @default.
- W1963579541 cites W2102109092 @default.
- W1963579541 cites W2102229939 @default.
- W1963579541 cites W2103503670 @default.
- W1963579541 cites W2104474203 @default.
- W1963579541 cites W2104548316 @default.
- W1963579541 cites W2105357365 @default.
- W1963579541 cites W2105637133 @default.
- W1963579541 cites W2107935259 @default.
- W1963579541 cites W2108204675 @default.
- W1963579541 cites W2110835349 @default.
- W1963579541 cites W2111211467 @default.
- W1963579541 cites W2111412754 @default.
- W1963579541 cites W2112011866 @default.
- W1963579541 cites W2112503796 @default.
- W1963579541 cites W2115897082 @default.
- W1963579541 cites W2118612771 @default.
- W1963579541 cites W2119904585 @default.
- W1963579541 cites W2122576818 @default.
- W1963579541 cites W2124510607 @default.
- W1963579541 cites W2131344386 @default.
- W1963579541 cites W2132382998 @default.
- W1963579541 cites W2132632499 @default.
- W1963579541 cites W2134061616 @default.
- W1963579541 cites W2137268987 @default.
- W1963579541 cites W2138178197 @default.
- W1963579541 cites W2139202079 @default.
- W1963579541 cites W2140042319 @default.
- W1963579541 cites W2140338292 @default.
- W1963579541 cites W2141504923 @default.
- W1963579541 cites W2143901293 @default.
- W1963579541 cites W2147710356 @default.
- W1963579541 cites W2149155242 @default.
- W1963579541 cites W2152528032 @default.
- W1963579541 cites W2154694904 @default.
- W1963579541 cites W2155302934 @default.
- W1963579541 cites W2156151768 @default.
- W1963579541 cites W2157108319 @default.
- W1963579541 cites W2160775938 @default.
- W1963579541 cites W2166699767 @default.
- W1963579541 cites W2170933940 @default.
- W1963579541 cites W4210531204 @default.
- W1963579541 cites W4232751510 @default.
- W1963579541 doi "https://doi.org/10.1128/jvi.01305-12" @default.