FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963584116> ?p ?o ?g. }

• W1963584116 endingPage "787" @default.
• W1963584116 startingPage "771" @default.
• W1963584116 abstract "The controlled delivery of nerve growth factor (NGF) to the peripheral nervous system has been shown to enhance nerve regeneration following injury, although the effect of release rate has not been previously studied with an affinity-based delivery system (DS). The goal of this research was to determine if the binding site affinity of the DS affected nerve regeneration in vivo using nerve guidance conduits (NGCs) in a 13-mm rat sciatic nerve defect. These DSs consisted of bi-domain peptides that varied in heparin-binding affinity, heparin and NGF, which binds to heparin with moderate affinity. Eight experimental groups were evaluated consisting of NGF with DS, control groups excluding one or more components of the DS within silicone conduits and nerve isografts. Nerves were harvested 6 weeks after treatment for analysis by histomorphometry. These DSs with NGF resulted in a higher frequency of nerve regeneration compared to control groups and were similar to the nerve isograft group in measures of nerve fiber density and percent neural tissue, but not in total nerve fiber count. In addition, these DSs with NGF contained a significantly greater percentage of larger diameter nerve fibers, suggesting more mature regenerating nerve content. While there were no differences in nerve regeneration due to varying peptide affinity with these DSs, their use with NGF enhanced peripheral nerve regeneration through a NGC across a critical nerve gap." @default.
• W1963584116 created "2016-06-24" @default.
• W1963584116 creator A5000647986 @default.
• W1963584116 creator A5012729674 @default.
• W1963584116 creator A5030188650 @default.
• W1963584116 creator A5052618290 @default.
• W1963584116 date "2010-01-01" @default.
• W1963584116 modified "2023-09-28" @default.
• W1963584116 title "Heparin-Binding-Affinity-Based Delivery Systems Releasing Nerve Growth Factor Enhance Sciatic Nerve Regeneration" @default.
• W1963584116 cites W1483655006 @default.
• W1963584116 cites W1581586115 @default.
• W1963584116 cites W1926705561 @default.
• W1963584116 cites W1965159814 @default.
• W1963584116 cites W1966305146 @default.
• W1963584116 cites W1969380265 @default.
• W1963584116 cites W1970004705 @default.
• W1963584116 cites W1970611360 @default.
• W1963584116 cites W1973501593 @default.
• W1963584116 cites W1986062352 @default.
• W1963584116 cites W1994329884 @default.
• W1963584116 cites W2000255951 @default.
• W1963584116 cites W2002764396 @default.
• W1963584116 cites W2005909933 @default.
• W1963584116 cites W2012132413 @default.
• W1963584116 cites W2013546498 @default.
• W1963584116 cites W2021289433 @default.
• W1963584116 cites W2023678209 @default.
• W1963584116 cites W2032717928 @default.
• W1963584116 cites W2033742681 @default.
• W1963584116 cites W2034533454 @default.
• W1963584116 cites W2038997019 @default.
• W1963584116 cites W2039439383 @default.
• W1963584116 cites W2040295454 @default.
• W1963584116 cites W2040997641 @default.
• W1963584116 cites W2048903275 @default.
• W1963584116 cites W2051466070 @default.
• W1963584116 cites W2054381865 @default.
• W1963584116 cites W2056681748 @default.
• W1963584116 cites W2061912562 @default.
• W1963584116 cites W2064899502 @default.
• W1963584116 cites W2065760012 @default.
• W1963584116 cites W2068936801 @default.
• W1963584116 cites W2069334439 @default.
• W1963584116 cites W2085762033 @default.
• W1963584116 cites W2086065499 @default.
• W1963584116 cites W2087018283 @default.
• W1963584116 cites W2087915712 @default.
• W1963584116 cites W2089640591 @default.
• W1963584116 cites W2095523831 @default.
• W1963584116 cites W2107514110 @default.
• W1963584116 cites W2121961969 @default.
• W1963584116 cites W2124423098 @default.
• W1963584116 cites W2136049931 @default.
• W1963584116 cites W2139741471 @default.
• W1963584116 cites W2162567095 @default.
• W1963584116 cites W2176312328 @default.
• W1963584116 cites W2225440776 @default.
• W1963584116 cites W2408760442 @default.
• W1963584116 cites W2416817584 @default.
• W1963584116 doi "https://doi.org/10.1163/156856209x445285" @default.
• W1963584116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20482984" @default.
• W1963584116 hasPublicationYear "2010" @default.
• W1963584116 type Work @default.
• W1963584116 sameAs 1963584116 @default.
• W1963584116 citedByCount "54" @default.
• W1963584116 countsByYear W19635841162012 @default.
• W1963584116 countsByYear W19635841162013 @default.
• W1963584116 countsByYear W19635841162014 @default.
• W1963584116 countsByYear W19635841162015 @default.
• W1963584116 countsByYear W19635841162016 @default.
• W1963584116 countsByYear W19635841162017 @default.
• W1963584116 countsByYear W19635841162018 @default.
• W1963584116 countsByYear W19635841162019 @default.
• W1963584116 countsByYear W19635841162020 @default.
• W1963584116 countsByYear W19635841162021 @default.
• W1963584116 countsByYear W19635841162023 @default.
• W1963584116 crossrefType "journal-article" @default.
• W1963584116 hasAuthorship W1963584116A5000647986 @default.
• W1963584116 hasAuthorship W1963584116A5012729674 @default.
• W1963584116 hasAuthorship W1963584116A5030188650 @default.
• W1963584116 hasAuthorship W1963584116A5052618290 @default.
• W1963584116 hasConcept C105702510 @default.
• W1963584116 hasConcept C126322002 @default.
• W1963584116 hasConcept C134018914 @default.
• W1963584116 hasConcept C136940099 @default.
• W1963584116 hasConcept C170493617 @default.
• W1963584116 hasConcept C171056886 @default.
• W1963584116 hasConcept C185592680 @default.
• W1963584116 hasConcept C2776823239 @default.
• W1963584116 hasConcept C2777557582 @default.
• W1963584116 hasConcept C2778423431 @default.
• W1963584116 hasConcept C2781149210 @default.
• W1963584116 hasConcept C529278444 @default.
• W1963584116 hasConcept C545314008 @default.
• W1963584116 hasConcept C71924100 @default.
• W1963584116 hasConcept C86803240 @default.
• W1963584116 hasConcept C93963793 @default.
• W1963584116 hasConcept C95444343 @default.

• next