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- W1963587204 abstract "The study was designed to reveal the distribution of various mast cell types in the forebrain of the adult sheep, hedgehog and rat. Based on their histochemical and immunocytochemical characteristics, mast cells were categorised as (1) connective tissue-type mast cells, staining metachromatically purple with the toluidine blue method, or pale red with the Alcian blue/safranin method, (2) mucosal-type or immature mast cells staining blue with the Alcian blue/safranin method and (3) serotonin immunopositive mast cells. All 3 types of brain mast cells in all species studied were located in both white and grey matter, often associated with intraparenchymal blood vessels. Their distribution pattern exhibited interspecies differences, while their number varied considerably not only between species but also between individuals of each species. A distributional left-right asymmetry, with more cells present on the left side, was observed in all species studied but it was most prominent in the sheep brain. In the sheep, mast cells were abundantly distributed in forebrain areas, while in the hedgehog and the rat forebrain, mast cells were less widely distributed and were relatively or substantially fewer in number respectively. A limited number of brain mast cells, in all 3 species, but primarily in the rat, were found to react both immunocytochemically to 5-HT antibody and histochemically with Alcian blue/safranin staining." @default.
- W1963587204 created "2016-06-24" @default.
- W1963587204 creator A5072084717 @default.
- W1963587204 creator A5075061574 @default.
- W1963587204 date "1999-11-01" @default.
- W1963587204 modified "2023-10-10" @default.
- W1963587204 title "Mast cells in the sheep, hedgehog and rat forebrain" @default.
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- W1963587204 doi "https://doi.org/10.1046/j.1469-7580.1999.19540577.x" @default.
- W1963587204 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1468028" @default.
- W1963587204 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10634696" @default.
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