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• W1963593702 abstract "Background Pancreatic duct (PD) stenting is beneficial for the treatment of pain in patients with PD strictures associated with chronic pancreatitis. Placement of metal stents has been reported but failed secondary to hyperplasia or migration. Objective To investigate the outcome of patients with symptomatic and refractory PD strictures who had temporary placement of a covered self-expandable metal stent (CSEMS). Design Patients with refractory PD strictures were offered temporary CSEMS placement. Pain scores were evaluated before and after CSEMS placement. Setting A tertiary-care center. Patients Six patients (4 men, mean age ± SD 55 ± 8 years) received a CSEMS, and 5 patients had removal of a CSEMS after a mean time of 92 days. Intervention Placement of CSEMS (8-mm or 10-mm diameter VIABIL) in the PD, with removal after 3 months. Main Outcome Measurements The pain score before and after stent placement and the sustained response after removal. Morbidity associated with stent placement and removal was also noted. Results Pain scores after CSEMS placement significantly improved (P = .024), from 6.4 to 1.6. Of the 5 patients who underwent CSEMS removal, 3 developed recurrent symptomatic pancreatic stricture, of whom 2 required repeat stenting with a larger-diameter CSEMS (10 mm) and 2 remained pain free. The CSEMS was not removed in 1 patient because pancreatic malignancy was diagnosed. There were no complications during placement or removal of CSEMSs. Limitation This was a pilot study. Conclusion Temporary placement of CSEMSs in patients with symptomatic refractory PD stricture offers transient relief of pain. Further investigation is needed to determine the optimal diameter and duration of placement. Pancreatic duct (PD) stenting is beneficial for the treatment of pain in patients with PD strictures associated with chronic pancreatitis. Placement of metal stents has been reported but failed secondary to hyperplasia or migration. To investigate the outcome of patients with symptomatic and refractory PD strictures who had temporary placement of a covered self-expandable metal stent (CSEMS). Patients with refractory PD strictures were offered temporary CSEMS placement. Pain scores were evaluated before and after CSEMS placement. A tertiary-care center. Six patients (4 men, mean age ± SD 55 ± 8 years) received a CSEMS, and 5 patients had removal of a CSEMS after a mean time of 92 days. Placement of CSEMS (8-mm or 10-mm diameter VIABIL) in the PD, with removal after 3 months. The pain score before and after stent placement and the sustained response after removal. Morbidity associated with stent placement and removal was also noted. Pain scores after CSEMS placement significantly improved (P = .024), from 6.4 to 1.6. Of the 5 patients who underwent CSEMS removal, 3 developed recurrent symptomatic pancreatic stricture, of whom 2 required repeat stenting with a larger-diameter CSEMS (10 mm) and 2 remained pain free. The CSEMS was not removed in 1 patient because pancreatic malignancy was diagnosed. There were no complications during placement or removal of CSEMSs. This was a pilot study. Temporary placement of CSEMSs in patients with symptomatic refractory PD stricture offers transient relief of pain. Further investigation is needed to determine the optimal diameter and duration of placement." @default.
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• W1963593702 date "2008-12-01" @default.
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• W1963593702 title "Temporary placement of a fully covered self-expandable metal stent in the pancreatic duct for management of symptomatic refractory chronic pancreatitis: preliminary data (with videos)" @default.
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• W1963593702 doi "https://doi.org/10.1016/j.gie.2008.06.011" @default.
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