Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963614892> ?p ?o ?g. }
- W1963614892 endingPage "e1002044" @default.
- W1963614892 startingPage "e1002044" @default.
- W1963614892 abstract "Differentiation of hyphae into specialized infection structures, known as appressoria, is a common feature of plant pathogenic fungi that penetrate the plant cuticle. Appressorium formation in U. maydis is triggered by environmental signals but the molecular mechanism of this hyphal differentiation is largely unknown. Infectious hyphae grow on the leaf surface by inserting regularly spaced retraction septa at the distal end of the tip cell leaving empty sections of collapsed hyphae behind. Here we show that formation of retraction septa is critical for appressorium formation and virulence in U. maydis. We demonstrate that the diaphanous-related formin Drf1 is necessary for actomyosin ring formation during septation of infectious hyphae. Drf1 acts as an effector of a Cdc42 GTPase signaling module, which also consists of the Cdc42-specific guanine nucleotide exchange factor Don1 and the Ste20-like kinase Don3. Deletion of drf1, don1 or don3 abolished formation of retraction septa resulting in reduced virulence. Appressorium formation in these mutants was not completely blocked but infection structures were found only at the tip of short filaments indicating that retraction septa are necessary for appressorium formation in extended infectious hyphae. In addition, appressoria of drf1 mutants penetrated the plant tissue less frequently." @default.
- W1963614892 created "2016-06-24" @default.
- W1963614892 creator A5046054205 @default.
- W1963614892 creator A5056748978 @default.
- W1963614892 creator A5067433930 @default.
- W1963614892 creator A5069600256 @default.
- W1963614892 creator A5071337684 @default.
- W1963614892 creator A5075291442 @default.
- W1963614892 date "2011-05-19" @default.
- W1963614892 modified "2023-10-07" @default.
- W1963614892 title "Septation of Infectious Hyphae Is Critical for Appressoria Formation and Virulence in the Smut Fungus Ustilago Maydis" @default.
- W1963614892 cites W1537866087 @default.
- W1963614892 cites W1570132182 @default.
- W1963614892 cites W1586463763 @default.
- W1963614892 cites W1603149304 @default.
- W1963614892 cites W1972033935 @default.
- W1963614892 cites W1973444064 @default.
- W1963614892 cites W1978984374 @default.
- W1963614892 cites W1983299578 @default.
- W1963614892 cites W1987266454 @default.
- W1963614892 cites W1988215817 @default.
- W1963614892 cites W1990850141 @default.
- W1963614892 cites W2007497503 @default.
- W1963614892 cites W2009023049 @default.
- W1963614892 cites W2010033051 @default.
- W1963614892 cites W2019125570 @default.
- W1963614892 cites W2024095351 @default.
- W1963614892 cites W2025823358 @default.
- W1963614892 cites W2030768863 @default.
- W1963614892 cites W2031168303 @default.
- W1963614892 cites W2034171135 @default.
- W1963614892 cites W2042639077 @default.
- W1963614892 cites W2046558624 @default.
- W1963614892 cites W2055466007 @default.
- W1963614892 cites W2059423539 @default.
- W1963614892 cites W2059436509 @default.
- W1963614892 cites W2061414976 @default.
- W1963614892 cites W2062358366 @default.
- W1963614892 cites W2062852486 @default.
- W1963614892 cites W2064071063 @default.
- W1963614892 cites W2064453200 @default.
- W1963614892 cites W2070119451 @default.
- W1963614892 cites W2073600426 @default.
- W1963614892 cites W2073670172 @default.
- W1963614892 cites W2074622507 @default.
- W1963614892 cites W2077592641 @default.
- W1963614892 cites W2082283628 @default.
- W1963614892 cites W2084559668 @default.
- W1963614892 cites W2090822193 @default.
- W1963614892 cites W2099452154 @default.
- W1963614892 cites W2108674739 @default.
- W1963614892 cites W2108822141 @default.
- W1963614892 cites W2113474142 @default.
- W1963614892 cites W2114048476 @default.
- W1963614892 cites W2122087650 @default.
- W1963614892 cites W2127107911 @default.
- W1963614892 cites W2129804465 @default.
- W1963614892 cites W2129890878 @default.
- W1963614892 cites W2130087466 @default.
- W1963614892 cites W2130186124 @default.
- W1963614892 cites W2131581472 @default.
- W1963614892 cites W2138585051 @default.
- W1963614892 cites W2138786218 @default.
- W1963614892 cites W2138972668 @default.
- W1963614892 cites W2139788876 @default.
- W1963614892 cites W2149694811 @default.
- W1963614892 cites W2151663881 @default.
- W1963614892 cites W2152298135 @default.
- W1963614892 cites W2167887094 @default.
- W1963614892 cites W2171847212 @default.
- W1963614892 cites W2177138958 @default.
- W1963614892 cites W2342986259 @default.
- W1963614892 cites W4236235546 @default.
- W1963614892 cites W4252538912 @default.
- W1963614892 doi "https://doi.org/10.1371/journal.ppat.1002044" @default.
- W1963614892 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3098242" @default.
- W1963614892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21625538" @default.
- W1963614892 hasPublicationYear "2011" @default.
- W1963614892 type Work @default.
- W1963614892 sameAs 1963614892 @default.
- W1963614892 citedByCount "36" @default.
- W1963614892 countsByYear W19636148922012 @default.
- W1963614892 countsByYear W19636148922013 @default.
- W1963614892 countsByYear W19636148922014 @default.
- W1963614892 countsByYear W19636148922015 @default.
- W1963614892 countsByYear W19636148922016 @default.
- W1963614892 countsByYear W19636148922017 @default.
- W1963614892 countsByYear W19636148922018 @default.
- W1963614892 countsByYear W19636148922019 @default.
- W1963614892 countsByYear W19636148922020 @default.
- W1963614892 countsByYear W19636148922021 @default.
- W1963614892 countsByYear W19636148922023 @default.
- W1963614892 crossrefType "journal-article" @default.
- W1963614892 hasAuthorship W1963614892A5046054205 @default.
- W1963614892 hasAuthorship W1963614892A5056748978 @default.
- W1963614892 hasAuthorship W1963614892A5067433930 @default.
- W1963614892 hasAuthorship W1963614892A5069600256 @default.
- W1963614892 hasAuthorship W1963614892A5071337684 @default.