FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963661748> ?p ?o ?g. }

• W1963661748 endingPage "182" @default.
• W1963661748 startingPage "174" @default.
• W1963661748 abstract "The behaviour of proinsulin and insulin in the presence of zinc suggests it plays an important role in insulin's production in the B-cell for the vast majority of animal species. The postulate that proinsulin forms a zinc containing hexamer soon after its synthesis and that this organization of the molecule is maintained through all the subsequent processes is supported by our observation that the proinsulin hexamer is converted readily into the insulin hexamer. In addition the zinc ions enhance proinsulin's solubility and render insulin insoluble. Zinc ions also appear to play an important role in the microcrystalline character of the precipitated insulin granule. There may be advantages in condensing the stored material in this way; it will reduce contact with the surrounding membrane where the converting, and possibly other enzymes, are thought to be located, and it will tend to exclude incompletely converted hexamers." @default.
• W1963661748 created "2016-06-24" @default.
• W1963661748 creator A5007156546 @default.
• W1963661748 creator A5008860475 @default.
• W1963661748 creator A5009307622 @default.
• W1963661748 creator A5010295475 @default.
• W1963661748 date "1980-09-01" @default.
• W1963661748 modified "2023-10-05" @default.
• W1963661748 title "Role of zinc in insulin biosynthesis" @default.
• W1963661748 cites W1491621039 @default.
• W1963661748 cites W1505799968 @default.
• W1963661748 cites W1518560201 @default.
• W1963661748 cites W1541842143 @default.
• W1963661748 cites W1605939661 @default.
• W1963661748 cites W1977949195 @default.
• W1963661748 cites W1989350176 @default.
• W1963661748 cites W2007915248 @default.
• W1963661748 cites W2012623603 @default.
• W1963661748 cites W2017134019 @default.
• W1963661748 cites W2029893493 @default.
• W1963661748 cites W2030943295 @default.
• W1963661748 cites W2031279528 @default.
• W1963661748 cites W2034169698 @default.
• W1963661748 cites W2053464931 @default.
• W1963661748 cites W2068583404 @default.
• W1963661748 cites W2081828201 @default.
• W1963661748 cites W2084529479 @default.
• W1963661748 cites W2100418952 @default.
• W1963661748 cites W2133768969 @default.
• W1963661748 cites W2138090458 @default.
• W1963661748 cites W2161869850 @default.
• W1963661748 cites W2193046993 @default.
• W1963661748 cites W2401935545 @default.
• W1963661748 cites W2405374525 @default.
• W1963661748 cites W2417187096 @default.
• W1963661748 cites W3024675195 @default.
• W1963661748 cites W4322698619 @default.
• W1963661748 cites W66245816 @default.
• W1963661748 cites W79276580 @default.
• W1963661748 cites W964503500 @default.
• W1963661748 doi "https://doi.org/10.1007/bf00275265" @default.
• W1963661748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6997118" @default.
• W1963661748 hasPublicationYear "1980" @default.
• W1963661748 type Work @default.
• W1963661748 sameAs 1963661748 @default.
• W1963661748 citedByCount "230" @default.
• W1963661748 countsByYear W19636617482012 @default.
• W1963661748 countsByYear W19636617482013 @default.
• W1963661748 countsByYear W19636617482014 @default.
• W1963661748 countsByYear W19636617482015 @default.
• W1963661748 countsByYear W19636617482016 @default.
• W1963661748 countsByYear W19636617482017 @default.
• W1963661748 countsByYear W19636617482018 @default.
• W1963661748 countsByYear W19636617482019 @default.
• W1963661748 countsByYear W19636617482020 @default.
• W1963661748 countsByYear W19636617482021 @default.
• W1963661748 countsByYear W19636617482022 @default.
• W1963661748 countsByYear W19636617482023 @default.
• W1963661748 crossrefType "journal-article" @default.
• W1963661748 hasAuthorship W1963661748A5007156546 @default.
• W1963661748 hasAuthorship W1963661748A5008860475 @default.
• W1963661748 hasAuthorship W1963661748A5009307622 @default.
• W1963661748 hasAuthorship W1963661748A5010295475 @default.
• W1963661748 hasBestOaLocation W19636617481 @default.
• W1963661748 hasConcept C126322002 @default.
• W1963661748 hasConcept C134018914 @default.
• W1963661748 hasConcept C151730666 @default.
• W1963661748 hasConcept C178790620 @default.
• W1963661748 hasConcept C181199279 @default.
• W1963661748 hasConcept C185592680 @default.
• W1963661748 hasConcept C189754071 @default.
• W1963661748 hasConcept C2779306644 @default.
• W1963661748 hasConcept C49760210 @default.
• W1963661748 hasConcept C535196362 @default.
• W1963661748 hasConcept C553450214 @default.
• W1963661748 hasConcept C55493867 @default.
• W1963661748 hasConcept C71924100 @default.
• W1963661748 hasConcept C86803240 @default.
• W1963661748 hasConcept C90061646 @default.
• W1963661748 hasConcept C95444343 @default.
• W1963661748 hasConceptScore W1963661748C126322002 @default.
• W1963661748 hasConceptScore W1963661748C134018914 @default.
• W1963661748 hasConceptScore W1963661748C151730666 @default.
• W1963661748 hasConceptScore W1963661748C178790620 @default.
• W1963661748 hasConceptScore W1963661748C181199279 @default.
• W1963661748 hasConceptScore W1963661748C185592680 @default.
• W1963661748 hasConceptScore W1963661748C189754071 @default.
• W1963661748 hasConceptScore W1963661748C2779306644 @default.
• W1963661748 hasConceptScore W1963661748C49760210 @default.
• W1963661748 hasConceptScore W1963661748C535196362 @default.
• W1963661748 hasConceptScore W1963661748C553450214 @default.
• W1963661748 hasConceptScore W1963661748C55493867 @default.
• W1963661748 hasConceptScore W1963661748C71924100 @default.
• W1963661748 hasConceptScore W1963661748C86803240 @default.
• W1963661748 hasConceptScore W1963661748C90061646 @default.
• W1963661748 hasConceptScore W1963661748C95444343 @default.
• W1963661748 hasIssue "3" @default.
• W1963661748 hasLocation W19636617481 @default.

• next