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- W1963669085 abstract "Results We registered 21 cases (median age 23, 47% male), out of which 47% had pulmonary TB previously. Clinical features were: abrupt onset 57%, headache 47%, fever 66%, vomiting 38%, respiratory symptoms 38%, coma 9.5%, cranial nerve palsy 19%, meningeal syndrome 38%, altered level of consciousness 19%. Laboratory findings of cerebrospinal fluid: clear aspect 81%, pleocytosis less than 500/cmm 66%, protein level more than 1 g/L 91%, glucose level less than 0.4 g/L 71%, decreased chlorine level 57%. Radiologically we found adenopathy in the pulmonary hilum in 24% of patients. Neurological complications occurred in 24% and drug related liver toxicity in 33%. We identified 47% of HIV-infected persons during 1987-1990. The interval between the diagnosis of the HIV-infection and the present hospital admission had a median of 6 years. The median value of the actual CD4 count was 92/cmm and viral load 570,000 copies/mL. Prior antiretroviral therapy (ART) was administered in 80% of patients with a median of 4 regimens. Only 19% of the patients were classified as adherent to the ART. The antiretroviral therapy administrated during the present hospital admission was: AZT/3TC + EFV – 9.5%, ABC/3TC + EFV – 9.5%, ABC/3TC + KLT – 4.7%, ABC + RAL + T20 – 4.7%. The median period of hospitalization was 10 days. The overall mortality during hospitalization was 43% and at 9 months it was 29%. The 9-month survival rate was 28%." @default.
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- W1963669085 date "2013-12-01" @default.
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- W1963669085 title "Tuberculous meningitis: presentation, diagnostic and outcome in HIV-infected individuals from regional center Iaşi" @default.
- W1963669085 doi "https://doi.org/10.1186/1471-2334-13-s1-p2" @default.
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