Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963670305> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1963670305 endingPage "524" @default.
- W1963670305 startingPage "517" @default.
- W1963670305 abstract "The single ip administration of Δ9-tetrahydrocannabinol (Δ9-THC) at doses of 10 and 50 mg/kg produces a dose-dependent increase in the contents of noradrenaline (NA) and adrenaline (AD) in the rat adrenal gland at the first phase (45–90 min), and thereafter, decline significantly (90–360 min). The content of adrenal dopamine (DA) continues to decrease sharply after the Δ9-THC administration and remains below normal even after 6 hr. Measurements of turnover of adrenal catecholamines made with the use of FLA-63, an inhibitor of dopamine β-hydroxylase and α-methyl-p-tyrosine (α-M-pt), an inhibitor of tyrosine hydroxylase, show that Δ9-THC given acutely both at low and at high dose (a) decreases the rate of synthesis and increases the rate of depletion of DA, (b) decreases the rate of depletion of NA and (c) increases the rate of depletion of AD. Treatment with Δ9-THC (10 mg/kg/day) for 21 consecutive days significantly elevates only the AD content with increase in its turnover rate. The cardiovascular responses, reported to occur after Δ9-THC administration, appear to be consistent with the increased adrenaline release observed in the present study." @default.
- W1963670305 created "2016-06-24" @default.
- W1963670305 creator A5035910191 @default.
- W1963670305 creator A5050610078 @default.
- W1963670305 creator A5076824604 @default.
- W1963670305 date "1976-09-01" @default.
- W1963670305 modified "2023-10-18" @default.
- W1963670305 title "Delta-9-tetrahydrocannabinol: effect on adrenal catecholamines" @default.
- W1963670305 cites W1410085 @default.
- W1963670305 cites W1566125473 @default.
- W1963670305 cites W1971926900 @default.
- W1963670305 cites W1980815137 @default.
- W1963670305 cites W1983455235 @default.
- W1963670305 cites W1988988549 @default.
- W1963670305 cites W1997397065 @default.
- W1963670305 cites W2006887372 @default.
- W1963670305 cites W2018532868 @default.
- W1963670305 cites W2032226335 @default.
- W1963670305 cites W2037080534 @default.
- W1963670305 cites W2045037378 @default.
- W1963670305 cites W2056112038 @default.
- W1963670305 cites W2059485966 @default.
- W1963670305 cites W2065882804 @default.
- W1963670305 cites W2069568434 @default.
- W1963670305 cites W2082382941 @default.
- W1963670305 cites W2087731498 @default.
- W1963670305 cites W2113806391 @default.
- W1963670305 cites W2128491194 @default.
- W1963670305 cites W2287714691 @default.
- W1963670305 cites W2303115160 @default.
- W1963670305 cites W2581368728 @default.
- W1963670305 cites W2745397711 @default.
- W1963670305 doi "https://doi.org/10.1016/0041-008x(76)90213-1" @default.
- W1963670305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/973224" @default.
- W1963670305 hasPublicationYear "1976" @default.
- W1963670305 type Work @default.
- W1963670305 sameAs 1963670305 @default.
- W1963670305 citedByCount "2" @default.
- W1963670305 crossrefType "journal-article" @default.
- W1963670305 hasAuthorship W1963670305A5035910191 @default.
- W1963670305 hasAuthorship W1963670305A5050610078 @default.
- W1963670305 hasAuthorship W1963670305A5076824604 @default.
- W1963670305 hasConcept C126322002 @default.
- W1963670305 hasConcept C134018914 @default.
- W1963670305 hasConcept C159167319 @default.
- W1963670305 hasConcept C170493617 @default.
- W1963670305 hasConcept C185592680 @default.
- W1963670305 hasConcept C2775894120 @default.
- W1963670305 hasConcept C2778563155 @default.
- W1963670305 hasConcept C2780694816 @default.
- W1963670305 hasConcept C2780871563 @default.
- W1963670305 hasConcept C2909767651 @default.
- W1963670305 hasConcept C513476851 @default.
- W1963670305 hasConcept C71924100 @default.
- W1963670305 hasConceptScore W1963670305C126322002 @default.
- W1963670305 hasConceptScore W1963670305C134018914 @default.
- W1963670305 hasConceptScore W1963670305C159167319 @default.
- W1963670305 hasConceptScore W1963670305C170493617 @default.
- W1963670305 hasConceptScore W1963670305C185592680 @default.
- W1963670305 hasConceptScore W1963670305C2775894120 @default.
- W1963670305 hasConceptScore W1963670305C2778563155 @default.
- W1963670305 hasConceptScore W1963670305C2780694816 @default.
- W1963670305 hasConceptScore W1963670305C2780871563 @default.
- W1963670305 hasConceptScore W1963670305C2909767651 @default.
- W1963670305 hasConceptScore W1963670305C513476851 @default.
- W1963670305 hasConceptScore W1963670305C71924100 @default.
- W1963670305 hasIssue "3" @default.
- W1963670305 hasLocation W19636703051 @default.
- W1963670305 hasLocation W19636703052 @default.
- W1963670305 hasOpenAccess W1963670305 @default.
- W1963670305 hasPrimaryLocation W19636703051 @default.
- W1963670305 hasRelatedWork W1512831350 @default.
- W1963670305 hasRelatedWork W1967765790 @default.
- W1963670305 hasRelatedWork W1974684692 @default.
- W1963670305 hasRelatedWork W1984467891 @default.
- W1963670305 hasRelatedWork W2009941709 @default.
- W1963670305 hasRelatedWork W2013389272 @default.
- W1963670305 hasRelatedWork W2062252989 @default.
- W1963670305 hasRelatedWork W2197598371 @default.
- W1963670305 hasRelatedWork W3136118295 @default.
- W1963670305 hasRelatedWork W4234517484 @default.
- W1963670305 hasVolume "37" @default.
- W1963670305 isParatext "false" @default.
- W1963670305 isRetracted "false" @default.
- W1963670305 magId "1963670305" @default.
- W1963670305 workType "article" @default.