Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963683413> ?p ?o ?g. }
- W1963683413 abstract "Bacteriophage phi 80 and lambda-phi 80 hybrid phage of the type lambda (QSR)80, in which the rightmost 10% of the lambda genome is replaced by corresponding phi 80 material, are unable to grow lytically in himA and hip/himD mutants of Escherichia coli K12 at 32 degrees. The genetic element responsible for the growth defect, rha, has been mapped to the (QSR)80 region and was located more precisely by restriction enzyme and DNA heteroduplex analysis of mutations that result in loss of the Rha phenotype. Such an Rha mutant carrying a 1.5-kb deletion beginning 0.58 kb from the right end of the chromosome and extending leftward locates the rha locus at least in part within this region of (QSR)80. In addition, a substitution derivative of lambda (QSR)80 was isolated which does not exhibit the Rha phenotype. In this phage, lambda-80hy95, the right half of the (QSR)80 region is replaced by DNA homologous to the 95-100% segment of lambda. In mixed infections in the himA42 host at 32 degrees, lambda + does not complement lambda (QSR)80 for growth and the burst size of the coinfecting lambda + is reduced in comparison to that in a single infection. Deletion mutants of lambda (QSR)80 that grow normally in himA42 at 32 degrees in single infections are inhibited for growth in mixed infections with lambda (QSR)80. These results suggest the existence of a trans-acting function which inhibits phage growth in the absence of HimA or Hip/HimD function. It is likely that the rha gene either encodes that function or indirectly controls its action." @default.
- W1963683413 created "2016-06-24" @default.
- W1963683413 creator A5033597379 @default.
- W1963683413 creator A5034978192 @default.
- W1963683413 date "1985-01-01" @default.
- W1963683413 modified "2023-09-25" @default.
- W1963683413 title "A φ80 function inhibitory for growth of lambdoid phage in him mutants of Escherichia coli deficient in integration host factor I. Genetic Analysis of the Rha phenotype" @default.
- W1963683413 cites W1515485474 @default.
- W1963683413 cites W1520741072 @default.
- W1963683413 cites W1525570188 @default.
- W1963683413 cites W1551709891 @default.
- W1963683413 cites W1560365186 @default.
- W1963683413 cites W1568603177 @default.
- W1963683413 cites W1594347014 @default.
- W1963683413 cites W1597077466 @default.
- W1963683413 cites W1600718860 @default.
- W1963683413 cites W1878364547 @default.
- W1963683413 cites W1969343550 @default.
- W1963683413 cites W1980085210 @default.
- W1963683413 cites W1996034651 @default.
- W1963683413 cites W2001033180 @default.
- W1963683413 cites W2004560773 @default.
- W1963683413 cites W2013300013 @default.
- W1963683413 cites W2014612066 @default.
- W1963683413 cites W2017140397 @default.
- W1963683413 cites W2017747950 @default.
- W1963683413 cites W2019193144 @default.
- W1963683413 cites W2022155144 @default.
- W1963683413 cites W2026862073 @default.
- W1963683413 cites W2027715013 @default.
- W1963683413 cites W2036184038 @default.
- W1963683413 cites W2038265624 @default.
- W1963683413 cites W2053618512 @default.
- W1963683413 cites W2054290067 @default.
- W1963683413 cites W2067474270 @default.
- W1963683413 cites W2069130544 @default.
- W1963683413 cites W2088195434 @default.
- W1963683413 cites W2133515446 @default.
- W1963683413 cites W2155635337 @default.
- W1963683413 cites W2161388653 @default.
- W1963683413 cites W2172407028 @default.
- W1963683413 cites W2410080988 @default.
- W1963683413 cites W25943917 @default.
- W1963683413 doi "https://doi.org/10.1016/0042-6822(85)90368-x" @default.
- W1963683413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3155885" @default.
- W1963683413 hasPublicationYear "1985" @default.
- W1963683413 type Work @default.
- W1963683413 sameAs 1963683413 @default.
- W1963683413 citedByCount "13" @default.
- W1963683413 countsByYear W19636834132013 @default.
- W1963683413 countsByYear W19636834132016 @default.
- W1963683413 crossrefType "journal-article" @default.
- W1963683413 hasAuthorship W1963683413A5033597379 @default.
- W1963683413 hasAuthorship W1963683413A5034978192 @default.
- W1963683413 hasBestOaLocation W19636834132 @default.
- W1963683413 hasConcept C104317684 @default.
- W1963683413 hasConcept C134494468 @default.
- W1963683413 hasConcept C136199206 @default.
- W1963683413 hasConcept C143065580 @default.
- W1963683413 hasConcept C153911025 @default.
- W1963683413 hasConcept C2776441376 @default.
- W1963683413 hasConcept C2781135666 @default.
- W1963683413 hasConcept C48292096 @default.
- W1963683413 hasConcept C54355233 @default.
- W1963683413 hasConcept C547475151 @default.
- W1963683413 hasConcept C552990157 @default.
- W1963683413 hasConcept C84597430 @default.
- W1963683413 hasConcept C86803240 @default.
- W1963683413 hasConcept C89423630 @default.
- W1963683413 hasConceptScore W1963683413C104317684 @default.
- W1963683413 hasConceptScore W1963683413C134494468 @default.
- W1963683413 hasConceptScore W1963683413C136199206 @default.
- W1963683413 hasConceptScore W1963683413C143065580 @default.
- W1963683413 hasConceptScore W1963683413C153911025 @default.
- W1963683413 hasConceptScore W1963683413C2776441376 @default.
- W1963683413 hasConceptScore W1963683413C2781135666 @default.
- W1963683413 hasConceptScore W1963683413C48292096 @default.
- W1963683413 hasConceptScore W1963683413C54355233 @default.
- W1963683413 hasConceptScore W1963683413C547475151 @default.
- W1963683413 hasConceptScore W1963683413C552990157 @default.
- W1963683413 hasConceptScore W1963683413C84597430 @default.
- W1963683413 hasConceptScore W1963683413C86803240 @default.
- W1963683413 hasConceptScore W1963683413C89423630 @default.
- W1963683413 hasLocation W19636834131 @default.
- W1963683413 hasLocation W19636834132 @default.
- W1963683413 hasLocation W19636834133 @default.
- W1963683413 hasOpenAccess W1963683413 @default.
- W1963683413 hasPrimaryLocation W19636834131 @default.
- W1963683413 hasRelatedWork W1502636341 @default.
- W1963683413 hasRelatedWork W1560920275 @default.
- W1963683413 hasRelatedWork W1562907868 @default.
- W1963683413 hasRelatedWork W1578060425 @default.
- W1963683413 hasRelatedWork W1605585845 @default.
- W1963683413 hasRelatedWork W1865671380 @default.
- W1963683413 hasRelatedWork W2002683511 @default.
- W1963683413 hasRelatedWork W2034347319 @default.
- W1963683413 hasRelatedWork W2169548525 @default.
- W1963683413 hasRelatedWork W2171194349 @default.
- W1963683413 isParatext "false" @default.
- W1963683413 isRetracted "false" @default.