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- W1963714679 abstract "The nucleotide sequence of the region between map positions 8.0 (HindIII site) and 11.8 (SmaI site) of adenovirus type 5 (Ad5) has been determined. Together with the sequences reported earlier (Van Ormondt et al., 1978; Maat and Van Ormondt, 1979) it encompasses the entire leftmost early region E1 of Ad5 DNA (4126 base pairs). The total sequence revealed a number of potential regulatory signals (promoter sites, ribosome binding sites, 3'-poly(A)-associated sequences), which confirm that region E1 is divided into subregions, E1a and E1b, and a region coding for semi-late viral protein IX. By taking into account the adenovirus 2 (Ad2) RNA-splicing data of Perricaudet et al. (1979; 1980) and the Ad2 RNA mapping data of Chow et al. (1979) we predict that E1a codes for polypeptides of 32, 26 and ca. 13 kd, and subregion E1b for polypeptides of 67 kd and 20 kd; the expected molecular weight of protein IX is 14.4 kd." @default.
- W1963714679 created "2016-06-24" @default.
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- W1963714679 date "1980-06-01" @default.
- W1963714679 modified "2023-09-23" @default.
- W1963714679 title "The nucleotide sequence of adenovirus type 5 early region El: the region between map positions 8.0 (HindIII site) and 11.8 (SmaI site)" @default.
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- W1963714679 doi "https://doi.org/10.1016/0378-1119(80)90140-7" @default.
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