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- W1963722986 abstract "1 Arachidonic acid(AA) (25-200 mug/kg) produced a dose-related increase in perfusion pressure in dog isolated hind limbs perfused with either blood or a platelet-free perfusate. 2 Prostaglandin E2 produced vasodilation while prostaglandin F2 alpha produced no vascular change at these administered doses. 3 Phentolamine did not alter the arachidonic acid response, eliminating possible alpha-adrenoceptor mediation. 4 Aspirin and idomethacin blocked the vasoconstrictor response to AA. 5 This study indicates that a vasoactive intermediate in prostaglandin synthesis can be elaborated in the absence of platelets." @default.
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- W1963722986 date "1977-02-01" @default.
- W1963722986 modified "2023-10-17" @default.
- W1963722986 title "VASOCONSTRICTOR RESPONSE TO ARACHIDONIC ACID IN THE ISOLATED HIND LIMB OF THE DOG" @default.
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- W1963722986 doi "https://doi.org/10.1111/j.1476-5381.1977.tb07489.x" @default.
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