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- W1963731415 abstract "A 7-year-old girl presented in August 1983 with a 4-month history of diffuse limb pains, loss of weight and general malaise. The pain had commenced in the neck and progressed to involve the right shoulder, both legs and spine. Examination revealed two firm right-sided cervical lymph nodes, 1 cm in diameter, and some smaller, firm nodes palpable over the occiput and in the inguinal regions. There was diffuse abdominal tenderness in the left upper quadrant but no other abnormal findings. Initial investigation showed a haemoglobin level of 7.9 g/dl (normochromic film), white cell count 5.9 x 109/1, ESR 90 mm in 1 h. Twenty-four-hour assay of 4-hydroxy-3-methoxymandolate was increased above 30 μmol/24 h (normal laboratory range < 30 μmol). Metadrenalin assay was 3.7/μmol/24h (normal laboratory range up to 7 μmol). Cystathionine was not detected in the urine. Chest radiography showed an enlarged left hilum associated with extensive paravertebral widening, and abdominal radiography showed calcification in the right suprarenal region. Skeletal survey identified multiple lytic areas involving mainly the metaphyses of the long bones and skull vault. There was a calcified area anterior to the pole of the right kidney on ultrasonography and also a left paravertebral mass indenting the pelvis of the left kidney. Bone marrow aspiration confirmed marrow involvement with tumour cells occupying some 40% of the nucleated cells. Metastatic neuroblastoma was diagnosed from cervical node biopsy. The primary was presumed to be within the right adrenal gland." @default.
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- W1963731415 date "1987-04-01" @default.
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- W1963731415 title "Imaging and treatment of disseminated neuroblastoma with131I-metaiodobenzylguanidine" @default.
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- W1963731415 doi "https://doi.org/10.1259/0007-1285-60-712-393" @default.
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