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- W1963781046 abstract "Clinical trials have shown that lamivudine suppresses HBV DNA levels in serum or causes it to become undetectable. The rate of sustained normalization of alanine transaminase (ALT) levels was more than 60%. Lai and colleagues treated 358 Chinese patients with chronic hepatitis with lamivudine. The primary end point was a reduction of at least two points in the Knodell necroinflammatory score. They recommended a dose of 100 mg daily. Multicenter studies have shown an efficacy response (necroinflammatory histologic improvement ALT normalization and HBV DNA clearance) in hepatitis B e antigen (HBeAg)-negative patients that is similar to that observed in patients with detectable HBeAg. This report presents that case of a woman with chronic viral hepatitis type B who became pregnant while receiving lamivudine. (excerpt)" @default.
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- W1963781046 date "2001-01-01" @default.
- W1963781046 modified "2023-09-25" @default.
- W1963781046 title "Lamivudine therapy for chronic hepatitis B virus infection and pregnancy: A case report" @default.
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- W1963781046 doi "https://doi.org/10.1016/s1201-9712(01)90038-4" @default.
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