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- W1963803225 abstract "In our stroke registry [1], non-rheumatic atrial fibrillation (AF) is the most frequent source of cardioembolic infarct (57.1% of cases) followed by valvular heart disease (20.3%) and coronary artery disease (18.2%). We agree with Lip and Zarifis that AF can also occur in patients with atherothrombotic stroke as epiphenomenon or as clinical manifestation of atherosclerotic disease (16.5% in our experience) [2]. In these circumstances, it is often difficult to distinguish between patients with AF as the cause of cardioembolic stroke and patients with AF as a symptom of atherothrombotic generalized disease. However, presumed pathogenesis of ischemic stroke should be confirmed by clinical data and results of work-up studies, i.e., echocardiography for assessing the presence or absence of systolic left ventricular dysfunction, increased left atrial diameter, or cardiac wall thrombus, and echo Doppler or arterial digital subtraction angiography of the supra-aortic trunks to confirm or to exclude the presence of severe carotid artery occlusive disease. In fact, urgent systematic examination of all acute stroke patients (with or without AF) by means of computed tomography [3] allows prompt diagnosis of intracerebral haemorrhage preventing the prescription of anticoagulant therapy, which is totally contraindicated in this stroke subtype." @default.
- W1963803225 created "2016-06-24" @default.
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- W1963803225 date "2000-09-01" @default.
- W1963803225 modified "2023-10-18" @default.
- W1963803225 title "Response to: Atrial fibrillation and stroke in patients admitted to a city center hospital serving a multicentre community" @default.
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- W1963803225 doi "https://doi.org/10.1016/s0167-5273(00)00352-1" @default.
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