Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963807722> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1963807722 endingPage "971" @default.
- W1963807722 startingPage "967" @default.
- W1963807722 abstract "The bio-elimination and organ retention of orally administered [14C]benzanthrone, an anthraquinone dye intermediate, were determined in control and ascorbic acid-supplemented guinea pigs. Urinary excretion of benzanthrone in control and ascorbic acid-treated animals during 96 hr was 27.9 and 30.5%, respectively, with peak elimination at 48 hr. Faecal elimination in control and supplemented animals during 96 hr was 24.5 and 38.8%, respectively, with a peak at 48 hr. The organ retention of radiolabelled benzanthrone at the end of 96 hr was of the order of 39% in control animals (gastrointestinal tract 16%; liver 22%; testis 1.2%); ascorbic acid supplementation reduced benzanthrone retention to 19.5% (gastro-intestinal tract 12.7%; liver 6.8%). Overall, pretreatment of guinea pigs with ascorbic acid caused a 32% enhancement in the clearance of radiolabelled benzanthrone through the urine and faeces, while organ retention was reduced by about 50%. A prophylactic dose of ascorbic acid may prevent benzanthrone-induced toxic symptoms in exposed workers." @default.
- W1963807722 created "2016-06-24" @default.
- W1963807722 creator A5017241283 @default.
- W1963807722 creator A5036744761 @default.
- W1963807722 creator A5043056171 @default.
- W1963807722 creator A5081681550 @default.
- W1963807722 date "1992-11-01" @default.
- W1963807722 modified "2023-10-14" @default.
- W1963807722 title "Effect of extraneous supplementation of ascorbic acid on the bio-disposition of benzanthrone in guinea pigs" @default.
- W1963807722 cites W154216494 @default.
- W1963807722 cites W1986106608 @default.
- W1963807722 cites W1986678246 @default.
- W1963807722 cites W1987178974 @default.
- W1963807722 cites W1993567316 @default.
- W1963807722 cites W1993751553 @default.
- W1963807722 cites W1996417761 @default.
- W1963807722 cites W2000255253 @default.
- W1963807722 cites W2005080920 @default.
- W1963807722 cites W2021798744 @default.
- W1963807722 cites W2022896643 @default.
- W1963807722 cites W2023280284 @default.
- W1963807722 cites W2028595388 @default.
- W1963807722 cites W2034989697 @default.
- W1963807722 cites W2036537745 @default.
- W1963807722 cites W2056802925 @default.
- W1963807722 cites W2065123397 @default.
- W1963807722 cites W2066925868 @default.
- W1963807722 cites W2070018987 @default.
- W1963807722 cites W2118389856 @default.
- W1963807722 cites W2170372934 @default.
- W1963807722 cites W2342045275 @default.
- W1963807722 cites W2406010488 @default.
- W1963807722 cites W2407642018 @default.
- W1963807722 cites W2408639676 @default.
- W1963807722 cites W2412830249 @default.
- W1963807722 cites W2473205897 @default.
- W1963807722 cites W2489309538 @default.
- W1963807722 cites W2613276273 @default.
- W1963807722 cites W2992022237 @default.
- W1963807722 cites W2485494562 @default.
- W1963807722 doi "https://doi.org/10.1016/0278-6915(92)90182-k" @default.
- W1963807722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1473790" @default.
- W1963807722 hasPublicationYear "1992" @default.
- W1963807722 type Work @default.
- W1963807722 sameAs 1963807722 @default.
- W1963807722 citedByCount "6" @default.
- W1963807722 countsByYear W19638077222015 @default.
- W1963807722 countsByYear W19638077222017 @default.
- W1963807722 crossrefType "journal-article" @default.
- W1963807722 hasAuthorship W1963807722A5017241283 @default.
- W1963807722 hasAuthorship W1963807722A5036744761 @default.
- W1963807722 hasAuthorship W1963807722A5043056171 @default.
- W1963807722 hasAuthorship W1963807722A5081681550 @default.
- W1963807722 hasConcept C10146269 @default.
- W1963807722 hasConcept C126322002 @default.
- W1963807722 hasConcept C185592680 @default.
- W1963807722 hasConcept C2778815084 @default.
- W1963807722 hasConcept C2780026642 @default.
- W1963807722 hasConcept C2780512811 @default.
- W1963807722 hasConcept C2986274086 @default.
- W1963807722 hasConcept C31903555 @default.
- W1963807722 hasConcept C55493867 @default.
- W1963807722 hasConcept C71924100 @default.
- W1963807722 hasConcept C98274493 @default.
- W1963807722 hasConceptScore W1963807722C10146269 @default.
- W1963807722 hasConceptScore W1963807722C126322002 @default.
- W1963807722 hasConceptScore W1963807722C185592680 @default.
- W1963807722 hasConceptScore W1963807722C2778815084 @default.
- W1963807722 hasConceptScore W1963807722C2780026642 @default.
- W1963807722 hasConceptScore W1963807722C2780512811 @default.
- W1963807722 hasConceptScore W1963807722C2986274086 @default.
- W1963807722 hasConceptScore W1963807722C31903555 @default.
- W1963807722 hasConceptScore W1963807722C55493867 @default.
- W1963807722 hasConceptScore W1963807722C71924100 @default.
- W1963807722 hasConceptScore W1963807722C98274493 @default.
- W1963807722 hasIssue "11" @default.
- W1963807722 hasLocation W19638077221 @default.
- W1963807722 hasLocation W19638077222 @default.
- W1963807722 hasOpenAccess W1963807722 @default.
- W1963807722 hasPrimaryLocation W19638077221 @default.
- W1963807722 hasRelatedWork W1981690828 @default.
- W1963807722 hasRelatedWork W1999174389 @default.
- W1963807722 hasRelatedWork W2044440668 @default.
- W1963807722 hasRelatedWork W2110464843 @default.
- W1963807722 hasRelatedWork W2278864606 @default.
- W1963807722 hasRelatedWork W2396995290 @default.
- W1963807722 hasRelatedWork W2410090426 @default.
- W1963807722 hasRelatedWork W2444240255 @default.
- W1963807722 hasRelatedWork W2991692886 @default.
- W1963807722 hasRelatedWork W4239226796 @default.
- W1963807722 hasVolume "30" @default.
- W1963807722 isParatext "false" @default.
- W1963807722 isRetracted "false" @default.
- W1963807722 magId "1963807722" @default.
- W1963807722 workType "article" @default.