FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963822275> ?p ?o ?g. }

• W1963822275 endingPage "e76787" @default.
• W1963822275 startingPage "e76787" @default.
• W1963822275 abstract "The RAS association domain family protein 1a gene (RASSF1A) is one of the tumor suppressor genes (TSG). Inactivation of RASSF1A is critical to the pathogenesis of cancer. Aberrant TSG methylation was considered an important epigenetic silencing mechanism in the progression of ovarian cancer. A number of studies have discussed association between RASSF1A promoter methylation and ovarian cancer. However, they were mostly based on a small number of samples and showed inconsist results, Therefore, we conducted a meta-analysis to better identify the association.Eligible studies were identified by searching the PubMed, EMBASE, Web of Science, and CNKI databases using a systematic searching strategy. We pooled the odds ratio (ORs) from individual studies using a fixed-effects model. We performed heterogeneity and publication bias analysis simultaneously.Thirteen studies, with 763 ovarian cancer patients and 438 controls were included in the meta-analysis. The frequencies of RASSF1A promoter methylation ranged from 30% to 58% (median is 48%) in the cancer group and 0 to 21% (median is 0) in the control group. The frequencies of RASSF1A promoter methylation in the cancer group were significantly higher than those in the control group. The pooled odds ratio was 11.17 (95% CI = 7.51-16.61) in the cancer group versus the corresponding control group under the fixed-effects model.The results suggested that RASSF1A promoter methylation had a strong association with ovarian cancer." @default.
• W1963822275 created "2016-06-24" @default.
• W1963822275 creator A5010381174 @default.
• W1963822275 creator A5021738797 @default.
• W1963822275 creator A5023171771 @default.
• W1963822275 creator A5024910931 @default.
• W1963822275 creator A5032249239 @default.
• W1963822275 creator A5033279980 @default.
• W1963822275 creator A5039078092 @default.
• W1963822275 creator A5057729078 @default.
• W1963822275 creator A5060447548 @default.
• W1963822275 creator A5073223053 @default.
• W1963822275 date "2013-10-08" @default.
• W1963822275 modified "2023-10-18" @default.
• W1963822275 title "Association between RASSF1A Promoter Methylation and Ovarian Cancer: A Meta-Analysis" @default.
• W1963822275 cites W1964348208 @default.
• W1963822275 cites W1964435302 @default.
• W1963822275 cites W1966598245 @default.
• W1963822275 cites W1970999805 @default.
• W1963822275 cites W2003673069 @default.
• W1963822275 cites W2006546769 @default.
• W1963822275 cites W2013432817 @default.
• W1963822275 cites W2024552817 @default.
• W1963822275 cites W2036884664 @default.
• W1963822275 cites W2051571765 @default.
• W1963822275 cites W2079846977 @default.
• W1963822275 cites W2082337086 @default.
• W1963822275 cites W2088985926 @default.
• W1963822275 cites W2106341289 @default.
• W1963822275 cites W2111927725 @default.
• W1963822275 cites W2113459016 @default.
• W1963822275 cites W2114656575 @default.
• W1963822275 cites W2120094396 @default.
• W1963822275 cites W2126235441 @default.
• W1963822275 cites W2126930838 @default.
• W1963822275 cites W2131099997 @default.
• W1963822275 cites W2132119564 @default.
• W1963822275 cites W2134852288 @default.
• W1963822275 cites W2139526606 @default.
• W1963822275 cites W2144263549 @default.
• W1963822275 cites W2157823046 @default.
• W1963822275 cites W2170538199 @default.
• W1963822275 cites W4234338065 @default.
• W1963822275 cites W4376561984 @default.
• W1963822275 doi "https://doi.org/10.1371/journal.pone.0076787" @default.
• W1963822275 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3792894" @default.
• W1963822275 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24116157" @default.
• W1963822275 hasPublicationYear "2013" @default.
• W1963822275 type Work @default.
• W1963822275 sameAs 1963822275 @default.
• W1963822275 citedByCount "17" @default.
• W1963822275 countsByYear W19638222752014 @default.
• W1963822275 countsByYear W19638222752016 @default.
• W1963822275 countsByYear W19638222752017 @default.
• W1963822275 countsByYear W19638222752019 @default.
• W1963822275 countsByYear W19638222752022 @default.
• W1963822275 countsByYear W19638222752023 @default.
• W1963822275 crossrefType "journal-article" @default.
• W1963822275 hasAuthorship W1963822275A5010381174 @default.
• W1963822275 hasAuthorship W1963822275A5021738797 @default.
• W1963822275 hasAuthorship W1963822275A5023171771 @default.
• W1963822275 hasAuthorship W1963822275A5024910931 @default.
• W1963822275 hasAuthorship W1963822275A5032249239 @default.
• W1963822275 hasAuthorship W1963822275A5033279980 @default.
• W1963822275 hasAuthorship W1963822275A5039078092 @default.
• W1963822275 hasAuthorship W1963822275A5057729078 @default.
• W1963822275 hasAuthorship W1963822275A5060447548 @default.
• W1963822275 hasAuthorship W1963822275A5073223053 @default.
• W1963822275 hasBestOaLocation W19638222751 @default.
• W1963822275 hasConcept C101762097 @default.
• W1963822275 hasConcept C104317684 @default.
• W1963822275 hasConcept C121608353 @default.
• W1963822275 hasConcept C126322002 @default.
• W1963822275 hasConcept C143998085 @default.
• W1963822275 hasConcept C150194340 @default.
• W1963822275 hasConcept C156957248 @default.
• W1963822275 hasConcept C190727270 @default.
• W1963822275 hasConcept C2780427987 @default.
• W1963822275 hasConcept C33288867 @default.
• W1963822275 hasConcept C41091548 @default.
• W1963822275 hasConcept C502942594 @default.
• W1963822275 hasConcept C54355233 @default.
• W1963822275 hasConcept C60644358 @default.
• W1963822275 hasConcept C71924100 @default.
• W1963822275 hasConcept C86803240 @default.
• W1963822275 hasConcept C95190672 @default.
• W1963822275 hasConceptScore W1963822275C101762097 @default.
• W1963822275 hasConceptScore W1963822275C104317684 @default.
• W1963822275 hasConceptScore W1963822275C121608353 @default.
• W1963822275 hasConceptScore W1963822275C126322002 @default.
• W1963822275 hasConceptScore W1963822275C143998085 @default.
• W1963822275 hasConceptScore W1963822275C150194340 @default.
• W1963822275 hasConceptScore W1963822275C156957248 @default.
• W1963822275 hasConceptScore W1963822275C190727270 @default.
• W1963822275 hasConceptScore W1963822275C2780427987 @default.
• W1963822275 hasConceptScore W1963822275C33288867 @default.
• W1963822275 hasConceptScore W1963822275C41091548 @default.
• W1963822275 hasConceptScore W1963822275C502942594 @default.

• next