Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963835797> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1963835797 endingPage "374" @default.
- W1963835797 startingPage "367" @default.
- W1963835797 abstract "We investigated the expression of an acquired host resistance against Staphylococcus aureus infection in mice. When C57BL/6 mice were immunized with viable S. aureus and challenged with S. aureus eight weeks later, the elimination of S. aureus from the spleen and liver was enhanced in the immunized mice compared with the nonimmunized mice. When gamma interferon (IFN-gamma(-/-)) mice were immunized and challenged, the bacterial numbers in the organs of immunized mice were comparable to those in the nonimmunized mice, suggesting that IFN-gamma plays a critical role in an acquired host resistance against S. aureus infection. IFN-gamma(-/-) mice produced the lower level of anti-S. aureus immunoglobulin M (IgM) and IgG2a antibodies compared with C57BL/6 mice. To elucidate the role of IFN-gamma produced during a challenge with S. aureus, a single injection of anti-IFN-gamma monoclonal antibody to mice was carried out 1 h before challenge. An acquired resistance against S. aureus infection was inhibited by injecting with anti-IFN-gamma monoclonal antibody. However, anti-IFN-gamma monoclonal antibody treatment failed to modulate anti-S. aureus IgM, IgG1 or IgG2a responses in these animals. These results demonstrated that IFN-gamma is required for an acquired resistance against S. aureus infection in mice. However, IFN-gamma induced during the challenge failed to affect the secondary antibody responses." @default.
- W1963835797 created "2016-06-24" @default.
- W1963835797 creator A5019789491 @default.
- W1963835797 creator A5052693860 @default.
- W1963835797 creator A5055280712 @default.
- W1963835797 creator A5074919264 @default.
- W1963835797 date "2006-04-01" @default.
- W1963835797 modified "2023-09-23" @default.
- W1963835797 title "The role of gamma interferon in acquired host resistance against<i>Staphylococcus aureus</i>infection in mice" @default.
- W1963835797 cites W1523347396 @default.
- W1963835797 cites W2015198171 @default.
- W1963835797 cites W2040395523 @default.
- W1963835797 cites W2120433995 @default.
- W1963835797 cites W2123347800 @default.
- W1963835797 cites W2125123418 @default.
- W1963835797 cites W2139576657 @default.
- W1963835797 cites W2171190373 @default.
- W1963835797 cites W2172658766 @default.
- W1963835797 doi "https://doi.org/10.1111/j.1574-695x.2005.00037.x" @default.
- W1963835797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16553809" @default.
- W1963835797 hasPublicationYear "2006" @default.
- W1963835797 type Work @default.
- W1963835797 sameAs 1963835797 @default.
- W1963835797 citedByCount "17" @default.
- W1963835797 countsByYear W19638357972014 @default.
- W1963835797 countsByYear W19638357972016 @default.
- W1963835797 countsByYear W19638357972017 @default.
- W1963835797 countsByYear W19638357972018 @default.
- W1963835797 countsByYear W19638357972020 @default.
- W1963835797 countsByYear W19638357972021 @default.
- W1963835797 crossrefType "journal-article" @default.
- W1963835797 hasAuthorship W1963835797A5019789491 @default.
- W1963835797 hasAuthorship W1963835797A5052693860 @default.
- W1963835797 hasAuthorship W1963835797A5055280712 @default.
- W1963835797 hasAuthorship W1963835797A5074919264 @default.
- W1963835797 hasBestOaLocation W19638357971 @default.
- W1963835797 hasConcept C159047783 @default.
- W1963835797 hasConcept C159654299 @default.
- W1963835797 hasConcept C203014093 @default.
- W1963835797 hasConcept C2777334864 @default.
- W1963835797 hasConcept C2779489039 @default.
- W1963835797 hasConcept C2780841837 @default.
- W1963835797 hasConcept C2780931953 @default.
- W1963835797 hasConcept C523546767 @default.
- W1963835797 hasConcept C542903549 @default.
- W1963835797 hasConcept C54355233 @default.
- W1963835797 hasConcept C86803240 @default.
- W1963835797 hasConcept C8891405 @default.
- W1963835797 hasConcept C89423630 @default.
- W1963835797 hasConceptScore W1963835797C159047783 @default.
- W1963835797 hasConceptScore W1963835797C159654299 @default.
- W1963835797 hasConceptScore W1963835797C203014093 @default.
- W1963835797 hasConceptScore W1963835797C2777334864 @default.
- W1963835797 hasConceptScore W1963835797C2779489039 @default.
- W1963835797 hasConceptScore W1963835797C2780841837 @default.
- W1963835797 hasConceptScore W1963835797C2780931953 @default.
- W1963835797 hasConceptScore W1963835797C523546767 @default.
- W1963835797 hasConceptScore W1963835797C542903549 @default.
- W1963835797 hasConceptScore W1963835797C54355233 @default.
- W1963835797 hasConceptScore W1963835797C86803240 @default.
- W1963835797 hasConceptScore W1963835797C8891405 @default.
- W1963835797 hasConceptScore W1963835797C89423630 @default.
- W1963835797 hasIssue "3" @default.
- W1963835797 hasLocation W19638357971 @default.
- W1963835797 hasLocation W19638357972 @default.
- W1963835797 hasOpenAccess W1963835797 @default.
- W1963835797 hasPrimaryLocation W19638357971 @default.
- W1963835797 hasRelatedWork W1948008185 @default.
- W1963835797 hasRelatedWork W2013698003 @default.
- W1963835797 hasRelatedWork W2015198171 @default.
- W1963835797 hasRelatedWork W2114298708 @default.
- W1963835797 hasRelatedWork W2147773763 @default.
- W1963835797 hasRelatedWork W2170267077 @default.
- W1963835797 hasRelatedWork W2322381039 @default.
- W1963835797 hasRelatedWork W2975636645 @default.
- W1963835797 hasRelatedWork W3008642713 @default.
- W1963835797 hasRelatedWork W3009296612 @default.
- W1963835797 hasVolume "46" @default.
- W1963835797 isParatext "false" @default.
- W1963835797 isRetracted "false" @default.
- W1963835797 magId "1963835797" @default.
- W1963835797 workType "article" @default.