FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963845669> ?p ?o ?g. }

• W1963845669 endingPage "109" @default.
• W1963845669 startingPage "104" @default.
• W1963845669 abstract "There are numerous diseases associated with abnormal hormonal regulation and these include cancers of the breast and prostate. There is substantial evidence that early hormonal perturbations (in utero or during early development) are associated with increased disease susceptibility later in life. These perturbations may arise from exposure to environmental agents or endocrine disruptors which mimic hormones and disrupt normal hormonal signaling. Epigenetic alterations have often been proposed as the underlying mechanism by which early hormonal perturbations may give rise to disease in adulthood. Currently, there is minimal evidence to support a direct link between early hormonal perturbations and epigenetic modifications; or between epigenetic alterations and subsequent onset of cancer. Given that epigenetic modifications may play an important role in hormone-dependent cancers, it is essential to better understand the relationship between the hormonal environment and epigenetic modifications in both normal and disease states. In this review, we highlight several important studies which support the hypothesis that: hormonal perturbations early in life may result in epigenetic changes that may modify hormone receptor function, thereby contributing to an increased risk of developing hormone-related cancers." @default.
• W1963845669 created "2016-06-24" @default.
• W1963845669 creator A5001363437 @default.
• W1963845669 creator A5020285542 @default.
• W1963845669 creator A5050075947 @default.
• W1963845669 creator A5065279464 @default.
• W1963845669 date "2009-04-01" @default.
• W1963845669 modified "2023-10-17" @default.
• W1963845669 title "The dynamic and static modification of the epigenome by hormones: A role in the developmental origin of hormone related cancers" @default.
• W1963845669 cites W1529224585 @default.
• W1963845669 cites W1593442063 @default.
• W1963845669 cites W1643500256 @default.
• W1963845669 cites W1967064280 @default.
• W1963845669 cites W1968931043 @default.
• W1963845669 cites W1969377280 @default.
• W1963845669 cites W1970579697 @default.
• W1963845669 cites W1971708895 @default.
• W1963845669 cites W1980673831 @default.
• W1963845669 cites W1986137039 @default.
• W1963845669 cites W1989873377 @default.
• W1963845669 cites W1990916340 @default.
• W1963845669 cites W1992264377 @default.
• W1963845669 cites W1994048261 @default.
• W1963845669 cites W2000926243 @default.
• W1963845669 cites W2001085078 @default.
• W1963845669 cites W2001316126 @default.
• W1963845669 cites W2002135196 @default.
• W1963845669 cites W2004172747 @default.
• W1963845669 cites W2006616069 @default.
• W1963845669 cites W2009121506 @default.
• W1963845669 cites W2013233792 @default.
• W1963845669 cites W2013521944 @default.
• W1963845669 cites W2020767030 @default.
• W1963845669 cites W2029868343 @default.
• W1963845669 cites W2032456711 @default.
• W1963845669 cites W2035176329 @default.
• W1963845669 cites W2036256995 @default.
• W1963845669 cites W2036986058 @default.
• W1963845669 cites W2037391637 @default.
• W1963845669 cites W2037728383 @default.
• W1963845669 cites W2038208040 @default.
• W1963845669 cites W2039576757 @default.
• W1963845669 cites W2039711181 @default.
• W1963845669 cites W2044272924 @default.
• W1963845669 cites W2044610823 @default.
• W1963845669 cites W2049651307 @default.
• W1963845669 cites W2053823503 @default.
• W1963845669 cites W2054823635 @default.
• W1963845669 cites W2058856687 @default.
• W1963845669 cites W2060559393 @default.
• W1963845669 cites W2061888284 @default.
• W1963845669 cites W2065782017 @default.
• W1963845669 cites W2066511342 @default.
• W1963845669 cites W2072526299 @default.
• W1963845669 cites W2075521327 @default.
• W1963845669 cites W2077249217 @default.
• W1963845669 cites W2080383769 @default.
• W1963845669 cites W2081195534 @default.
• W1963845669 cites W2082270407 @default.
• W1963845669 cites W2085745662 @default.
• W1963845669 cites W2086857599 @default.
• W1963845669 cites W2086882324 @default.
• W1963845669 cites W2087025655 @default.
• W1963845669 cites W2089003540 @default.
• W1963845669 cites W2090590520 @default.
• W1963845669 cites W2091101545 @default.
• W1963845669 cites W2092685754 @default.
• W1963845669 cites W2099008462 @default.
• W1963845669 cites W2099292393 @default.
• W1963845669 cites W2101037833 @default.
• W1963845669 cites W2103992678 @default.
• W1963845669 cites W2105381028 @default.
• W1963845669 cites W2106611357 @default.
• W1963845669 cites W2106681373 @default.
• W1963845669 cites W2108900261 @default.
• W1963845669 cites W2110278699 @default.
• W1963845669 cites W2124205544 @default.
• W1963845669 cites W2126689461 @default.
• W1963845669 cites W2127494723 @default.
• W1963845669 cites W2129175864 @default.
• W1963845669 cites W2130239724 @default.
• W1963845669 cites W2132783596 @default.
• W1963845669 cites W2133918562 @default.
• W1963845669 cites W2134027309 @default.
• W1963845669 cites W2135128012 @default.
• W1963845669 cites W2135752342 @default.
• W1963845669 cites W2136492640 @default.
• W1963845669 cites W2138976334 @default.
• W1963845669 cites W2141410747 @default.
• W1963845669 cites W2148043422 @default.
• W1963845669 cites W2154755276 @default.
• W1963845669 cites W2166415807 @default.
• W1963845669 cites W2166903671 @default.
• W1963845669 cites W2171788646 @default.
• W1963845669 cites W4253738810 @default.
• W1963845669 doi "https://doi.org/10.1016/j.bbcan.2008.12.001" @default.
• W1963845669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19166905" @default.
• W1963845669 hasPublicationYear "2009" @default.

• next