Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963869966> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1963869966 abstract "To evaluate the effect of an active fraction from Leptadenia reticulata leaves on serum glucose and lipid profile in normal and diabetic rats.Diabetes was induced by streptozotocin in Wistar rats. Petroleum ether, ethyl acetate, and ethanol extracts of Leptadenia reticulata leaves were administered orally at a dose of 200 mg·kg(-1), p.o. Metformin was used as standard anti diabetic drug (50 mg·kg(-1), p.o). The extract showing higher antidiabetic activity was subjected to column chromatography and led to the isolation of an active fraction, which was given trivial name Lr-1. Lr-1 (100 mg·kg(-1), p.o.) was studied for its hypoglycemic and hypolipidemic potential.The ethanol extract was found to lower the FBG level significantly (P < 0.05) in diabetic rats. Lr-1 caused a significant (P < 0.05) reduction in FBG level, and additionally it caused reduction in cholesterol, triglyceride levels, and an improvement in the HDL level in diabetic rats.Reduction in the FBG, cholesterol, triglyceride levels, and an improvement in the HDL by Lr-1 indicates that Lr-1 has antidiabetic activity, along with cardioprotective potential, and provides a scientific rationale for the use as an antidiabetic agent." @default.
- W1963869966 created "2016-06-24" @default.
- W1963869966 creator A5031791892 @default.
- W1963869966 creator A5086845272 @default.
- W1963869966 date "2014-06-01" @default.
- W1963869966 modified "2023-09-26" @default.
- W1963869966 title "Effect of an active fraction isolated from the leaf extract of Leptadenia reticulata on plasma glucose concentration and lipid profile in streptozotocin-induced diabetic rats" @default.
- W1963869966 cites W1274786373 @default.
- W1963869966 cites W1981626587 @default.
- W1963869966 cites W1987667569 @default.
- W1963869966 cites W1994003287 @default.
- W1963869966 cites W2005704651 @default.
- W1963869966 cites W2049702067 @default.
- W1963869966 cites W2060854807 @default.
- W1963869966 cites W2095612977 @default.
- W1963869966 cites W2104201214 @default.
- W1963869966 cites W2106755944 @default.
- W1963869966 cites W2115306715 @default.
- W1963869966 cites W2179166623 @default.
- W1963869966 cites W2257505506 @default.
- W1963869966 cites W3038334998 @default.
- W1963869966 cites W41922719 @default.
- W1963869966 doi "https://doi.org/10.1016/s1875-5364(14)60071-6" @default.
- W1963869966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24969527" @default.
- W1963869966 hasPublicationYear "2014" @default.
- W1963869966 type Work @default.
- W1963869966 sameAs 1963869966 @default.
- W1963869966 citedByCount "2" @default.
- W1963869966 countsByYear W19638699662015 @default.
- W1963869966 countsByYear W19638699662017 @default.
- W1963869966 crossrefType "journal-article" @default.
- W1963869966 hasAuthorship W1963869966A5031791892 @default.
- W1963869966 hasAuthorship W1963869966A5086845272 @default.
- W1963869966 hasConcept C126322002 @default.
- W1963869966 hasConcept C134018914 @default.
- W1963869966 hasConcept C185592680 @default.
- W1963869966 hasConcept C2776148806 @default.
- W1963869966 hasConcept C2778163477 @default.
- W1963869966 hasConcept C2778270857 @default.
- W1963869966 hasConcept C2778913445 @default.
- W1963869966 hasConcept C2779280383 @default.
- W1963869966 hasConcept C2779858419 @default.
- W1963869966 hasConcept C2780161600 @default.
- W1963869966 hasConcept C2780323712 @default.
- W1963869966 hasConcept C3020574416 @default.
- W1963869966 hasConcept C43617362 @default.
- W1963869966 hasConcept C4725764 @default.
- W1963869966 hasConcept C55493867 @default.
- W1963869966 hasConcept C555293320 @default.
- W1963869966 hasConcept C71924100 @default.
- W1963869966 hasConcept C98274493 @default.
- W1963869966 hasConceptScore W1963869966C126322002 @default.
- W1963869966 hasConceptScore W1963869966C134018914 @default.
- W1963869966 hasConceptScore W1963869966C185592680 @default.
- W1963869966 hasConceptScore W1963869966C2776148806 @default.
- W1963869966 hasConceptScore W1963869966C2778163477 @default.
- W1963869966 hasConceptScore W1963869966C2778270857 @default.
- W1963869966 hasConceptScore W1963869966C2778913445 @default.
- W1963869966 hasConceptScore W1963869966C2779280383 @default.
- W1963869966 hasConceptScore W1963869966C2779858419 @default.
- W1963869966 hasConceptScore W1963869966C2780161600 @default.
- W1963869966 hasConceptScore W1963869966C2780323712 @default.
- W1963869966 hasConceptScore W1963869966C3020574416 @default.
- W1963869966 hasConceptScore W1963869966C43617362 @default.
- W1963869966 hasConceptScore W1963869966C4725764 @default.
- W1963869966 hasConceptScore W1963869966C55493867 @default.
- W1963869966 hasConceptScore W1963869966C555293320 @default.
- W1963869966 hasConceptScore W1963869966C71924100 @default.
- W1963869966 hasConceptScore W1963869966C98274493 @default.
- W1963869966 hasLocation W19638699661 @default.
- W1963869966 hasLocation W19638699662 @default.
- W1963869966 hasOpenAccess W1963869966 @default.
- W1963869966 hasPrimaryLocation W19638699661 @default.
- W1963869966 hasRelatedWork W1544762314 @default.
- W1963869966 hasRelatedWork W1980712583 @default.
- W1963869966 hasRelatedWork W1995317287 @default.
- W1963869966 hasRelatedWork W2086894460 @default.
- W1963869966 hasRelatedWork W2141037190 @default.
- W1963869966 hasRelatedWork W2168904958 @default.
- W1963869966 hasRelatedWork W2258365808 @default.
- W1963869966 hasRelatedWork W2953465233 @default.
- W1963869966 hasRelatedWork W2981207488 @default.
- W1963869966 hasRelatedWork W68583009 @default.
- W1963869966 isParatext "false" @default.
- W1963869966 isRetracted "false" @default.
- W1963869966 magId "1963869966" @default.
- W1963869966 workType "article" @default.