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- W1963916174 abstract "An efficient and practical method has been manifested for the diversity-oriented synthesis of quinolines via Friedländer annulation reaction for the generation of a wide range of structurally interesting and pharmacologically significant compounds by using ceric ammonium nitrate as a catalyst (10 mol %) at ambient temperature in 45 min. A variety of functional groups are introduced at various positions of the quinoline moiety, and further the diversity of the core skeleton was expanded at R1 and R2 positions by the synthesis of various hybrids. Initial screening of the compounds for cytotoxicity against a series of cancer cell lines showed promising results." @default.
- W1963916174 created "2016-06-24" @default.
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- W1963916174 date "2009-12-11" @default.
- W1963916174 modified "2023-10-10" @default.
- W1963916174 title "Diversity-Oriented Synthesis of Quinolines via Friedländer Annulation Reaction under Mild Catalytic Conditions" @default.
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- W1963916174 doi "https://doi.org/10.1021/cc900129t" @default.
- W1963916174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20000618" @default.
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