FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963973907> ?p ?o ?g. }

• W1963973907 endingPage "408" @default.
• W1963973907 startingPage "398" @default.
• W1963973907 abstract "The primary structure of glutathione S-transferase (GST) pi from a single human placenta was determined. The structure was established by chemical characterization of tryptic and cyanogen bromide peptides as well as automated sequence analysis of the intact enzyme. The structural analysis indicated that the protein is comprised of 209 amino acid residues and gave no evidence of post-translational modifications. The amino acid sequence differed from that of the deduced amino acid sequence determined by nucleotide sequence analysis of a cDNA clone (Kano, T., Sakai, M., and Muramatsu, M., 1987, Cancer Res. 47, 5626-5630) at position 104 which contained both valine and isoleucine whereas the deduced sequence from nucleotide sequence analysis identified only isoleucine at this position. These results demonstrated that in the one individual placenta studied at least two GST pi genes are coexpressed, probably as a result of allelomorphism. Computer assisted consensus sequence evaluation identified a hydrophobic region in GST pi (residues 155-181) that was predicted to be either a buried transmembrane helical region or a signal sequence region. The significance of this hydrophobic region was interpreted in relation to the mode of action of the enzyme especially in regard to the potential involvement of a histidine in the active site mechanism. A comparison of the chemical similarity of five known human GST complete enzyme structures, one of pi, one of mu, two of alpha, and one microsomal, gave evidence that all five enzymes have evolved by a divergent evolutionary process after gene duplication, with the microsomal enzyme representing the most divergent form." @default.
• W1963973907 created "2016-06-24" @default.
• W1963973907 creator A5013534230 @default.
• W1963973907 creator A5018098828 @default.
• W1963973907 creator A5021056534 @default.
• W1963973907 creator A5028717495 @default.
• W1963973907 creator A5029866856 @default.
• W1963973907 creator A5052673002 @default.
• W1963973907 creator A5053977534 @default.
• W1963973907 creator A5078733718 @default.
• W1963973907 date "1990-05-01" @default.
• W1963973907 modified "2023-09-28" @default.
• W1963973907 title "Primary and secondary structural analyses of glutathione S-transferase π from human placenta" @default.
• W1963973907 cites W1205902433 @default.
• W1963973907 cites W1518482677 @default.
• W1963973907 cites W1529027655 @default.
• W1963973907 cites W1569344741 @default.
• W1963973907 cites W1575291432 @default.
• W1963973907 cites W1581414347 @default.
• W1963973907 cites W1660272883 @default.
• W1963973907 cites W1807939617 @default.
• W1963973907 cites W1968525222 @default.
• W1963973907 cites W1969419384 @default.
• W1963973907 cites W1970734978 @default.
• W1963973907 cites W2010601153 @default.
• W1963973907 cites W2012320131 @default.
• W1963973907 cites W2017701976 @default.
• W1963973907 cites W2018816542 @default.
• W1963973907 cites W2019909028 @default.
• W1963973907 cites W2026582002 @default.
• W1963973907 cites W2028943856 @default.
• W1963973907 cites W2030638652 @default.
• W1963973907 cites W2033203102 @default.
• W1963973907 cites W2033643793 @default.
• W1963973907 cites W2035564383 @default.
• W1963973907 cites W2037102375 @default.
• W1963973907 cites W2040855698 @default.
• W1963973907 cites W2050191270 @default.
• W1963973907 cites W2050891683 @default.
• W1963973907 cites W2056530947 @default.
• W1963973907 cites W2073859835 @default.
• W1963973907 cites W2077697537 @default.
• W1963973907 cites W2087344385 @default.
• W1963973907 cites W2126719129 @default.
• W1963973907 cites W2160883809 @default.
• W1963973907 cites W2229990068 @default.
• W1963973907 cites W4293247451 @default.
• W1963973907 doi "https://doi.org/10.1016/0003-9861(90)90277-6" @default.
• W1963973907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2327795" @default.
• W1963973907 hasPublicationYear "1990" @default.
• W1963973907 type Work @default.
• W1963973907 sameAs 1963973907 @default.
• W1963973907 citedByCount "107" @default.
• W1963973907 countsByYear W19639739072012 @default.
• W1963973907 countsByYear W19639739072013 @default.
• W1963973907 countsByYear W19639739072014 @default.
• W1963973907 countsByYear W19639739072018 @default.
• W1963973907 countsByYear W19639739072021 @default.
• W1963973907 crossrefType "journal-article" @default.
• W1963973907 hasAuthorship W1963973907A5013534230 @default.
• W1963973907 hasAuthorship W1963973907A5018098828 @default.
• W1963973907 hasAuthorship W1963973907A5021056534 @default.
• W1963973907 hasAuthorship W1963973907A5028717495 @default.
• W1963973907 hasAuthorship W1963973907A5029866856 @default.
• W1963973907 hasAuthorship W1963973907A5052673002 @default.
• W1963973907 hasAuthorship W1963973907A5053977534 @default.
• W1963973907 hasAuthorship W1963973907A5078733718 @default.
• W1963973907 hasConcept C104317684 @default.
• W1963973907 hasConcept C167625842 @default.
• W1963973907 hasConcept C181199279 @default.
• W1963973907 hasConcept C2776580952 @default.
• W1963973907 hasConcept C2777093645 @default.
• W1963973907 hasConcept C2777305461 @default.
• W1963973907 hasConcept C2778460671 @default.
• W1963973907 hasConcept C515207424 @default.
• W1963973907 hasConcept C55493867 @default.
• W1963973907 hasConcept C61053724 @default.
• W1963973907 hasConcept C84148353 @default.
• W1963973907 hasConcept C86803240 @default.
• W1963973907 hasConcept C92825506 @default.
• W1963973907 hasConceptScore W1963973907C104317684 @default.
• W1963973907 hasConceptScore W1963973907C167625842 @default.
• W1963973907 hasConceptScore W1963973907C181199279 @default.
• W1963973907 hasConceptScore W1963973907C2776580952 @default.
• W1963973907 hasConceptScore W1963973907C2777093645 @default.
• W1963973907 hasConceptScore W1963973907C2777305461 @default.
• W1963973907 hasConceptScore W1963973907C2778460671 @default.
• W1963973907 hasConceptScore W1963973907C515207424 @default.
• W1963973907 hasConceptScore W1963973907C55493867 @default.
• W1963973907 hasConceptScore W1963973907C61053724 @default.
• W1963973907 hasConceptScore W1963973907C84148353 @default.
• W1963973907 hasConceptScore W1963973907C86803240 @default.
• W1963973907 hasConceptScore W1963973907C92825506 @default.
• W1963973907 hasIssue "2" @default.
• W1963973907 hasLocation W19639739071 @default.
• W1963973907 hasLocation W19639739072 @default.
• W1963973907 hasOpenAccess W1963973907 @default.
• W1963973907 hasPrimaryLocation W19639739071 @default.

• next