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- W1963994312 abstract "Knowledge of the clinical and economic impact of antimicrobial resistance is useful to influence programs and behavior in healthcare facilities, to guide policy makers and funding agencies, to define the prognosis of individual patients and to stimulate interest in developing new antimicrobial agents and therapies. There are a variety of important issues that must be considered when designing or interpreting studies into the clinical and economic outcomes associated with antimicrobial resistance. One of the most misunderstood issues is how to measure cost appropriately. Although imperfect, existing data show that there is an association between antimicrobial resistance in Staphylococcus aureus, enterococci and Gram-negative bacilli and increases in mortality, morbidity, length of hospitalization and cost of healthcare. Patients with infections due to antimicrobial-resistant organisms have higher costs (US$6000–30,000) than do patients with infections due to antimicrobial-susceptible organisms; the difference in cost is even greater when patients infected with antimicrobial-resistant organisms are compared with patients without infection. Given limited budgets, knowledge of the clinical and economic impact of antibiotic-resistant bacterial infections, coupled with the benefits of specific interventions targeted to reduce these infections, will allow for optimal control and improved patient safety. In this review, the authors discuss a variety of important issues that must be considered when designing or interpreting studies of the clinical and economic outcomes associated with antimicrobial resistance. Representative literature is reviewed regarding the associations between antimicrobial resistance in specific pathogens and adverse outcomes, including increased mortality, length of hospital stay and cost." @default.
- W1963994312 created "2016-06-24" @default.
- W1963994312 creator A5018437292 @default.
- W1963994312 creator A5068281344 @default.
- W1963994312 creator A5078149638 @default.
- W1963994312 date "2008-10-01" @default.
- W1963994312 modified "2023-10-03" @default.
- W1963994312 title "Clinical and economic burden of antimicrobial resistance" @default.
- W1963994312 cites W1580051107 @default.
- W1963994312 cites W176620749 @default.
- W1963994312 cites W1903921336 @default.
- W1963994312 cites W1905853441 @default.
- W1963994312 cites W1964453855 @default.
- W1963994312 cites W1970515239 @default.
- W1963994312 cites W1972513618 @default.
- W1963994312 cites W1975150477 @default.
- W1963994312 cites W1976048465 @default.
- W1963994312 cites W1979907199 @default.
- W1963994312 cites W1982297704 @default.
- W1963994312 cites W1984647443 @default.
- W1963994312 cites W1993966173 @default.
- W1963994312 cites W1995973991 @default.
- W1963994312 cites W2000445173 @default.
- W1963994312 cites W2002773042 @default.
- W1963994312 cites W2003503791 @default.
- W1963994312 cites W2005281823 @default.
- W1963994312 cites W2005372742 @default.
- W1963994312 cites W2007568044 @default.
- W1963994312 cites W2008561095 @default.
- W1963994312 cites W2029715279 @default.
- W1963994312 cites W2030501295 @default.
- W1963994312 cites W2034440069 @default.
- W1963994312 cites W2035005547 @default.
- W1963994312 cites W2035031233 @default.
- W1963994312 cites W2042353763 @default.
- W1963994312 cites W2044087791 @default.
- W1963994312 cites W2045908270 @default.
- W1963994312 cites W2051225320 @default.
- W1963994312 cites W2058175683 @default.
- W1963994312 cites W2058341549 @default.
- W1963994312 cites W2070958433 @default.
- W1963994312 cites W2072146778 @default.
- W1963994312 cites W2081380761 @default.
- W1963994312 cites W2084993561 @default.
- W1963994312 cites W2088048768 @default.
- W1963994312 cites W2088736329 @default.
- W1963994312 cites W2097335739 @default.
- W1963994312 cites W2097424391 @default.
- W1963994312 cites W2102463930 @default.
- W1963994312 cites W2102651841 @default.
- W1963994312 cites W2102672963 @default.
- W1963994312 cites W2102963376 @default.
- W1963994312 cites W2105986346 @default.
- W1963994312 cites W2106431018 @default.
- W1963994312 cites W2107810227 @default.
- W1963994312 cites W2108934165 @default.
- W1963994312 cites W2111155119 @default.
- W1963994312 cites W2113662648 @default.
- W1963994312 cites W2113703185 @default.
- W1963994312 cites W2114231217 @default.
- W1963994312 cites W2116816874 @default.
- W1963994312 cites W2117413871 @default.
- W1963994312 cites W2121789287 @default.
- W1963994312 cites W2122710851 @default.
- W1963994312 cites W2123184982 @default.
- W1963994312 cites W2125008811 @default.
- W1963994312 cites W2127008375 @default.
- W1963994312 cites W2127882230 @default.
- W1963994312 cites W2128956519 @default.
- W1963994312 cites W2132718508 @default.
- W1963994312 cites W2133100008 @default.
- W1963994312 cites W2133902131 @default.
- W1963994312 cites W2134879805 @default.
- W1963994312 cites W2135161828 @default.
- W1963994312 cites W2135356952 @default.
- W1963994312 cites W2144792110 @default.
- W1963994312 cites W2145660125 @default.
- W1963994312 cites W2146295819 @default.
- W1963994312 cites W2148440281 @default.
- W1963994312 cites W2148861439 @default.
- W1963994312 cites W2149094043 @default.
- W1963994312 cites W2150188452 @default.
- W1963994312 cites W2153868993 @default.
- W1963994312 cites W2154007902 @default.
- W1963994312 cites W2155745631 @default.
- W1963994312 cites W2156075029 @default.
- W1963994312 cites W2159585072 @default.
- W1963994312 cites W2163392158 @default.
- W1963994312 cites W2163832044 @default.
- W1963994312 cites W2164381883 @default.
- W1963994312 cites W2167973138 @default.
- W1963994312 cites W2168836899 @default.
- W1963994312 cites W2169455258 @default.
- W1963994312 cites W2169619449 @default.
- W1963994312 cites W2170283209 @default.
- W1963994312 cites W3144776050 @default.
- W1963994312 cites W4241728343 @default.
- W1963994312 cites W4251139979 @default.