FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1963997977> ?p ?o ?g. }

• W1963997977 endingPage "112" @default.
• W1963997977 startingPage "103" @default.
• W1963997977 abstract "Rotaviral diarrheal illness is one of the most common infectious diseases in children worldwide, but our understanding of its pathophysiology is limited. This study examines whether the enhanced net chloride secretion during rotavirus infection in young rabbits may occur as a result of hypersecretion in crypt cells that would exceed the substantial Cl(-) reabsorption observed in villi. By using a rapid filtration technique, we evaluated transport of (36)Cl and D-(14)C glucose across brush border membrane (BBM) vesicles purified from villus tip and crypt cells isolated in parallel from the entire small intestine. Rotavirus infection impaired SGLT1-mediated Na(+)-D-glucose symport activity in both villus and crypt cell BBM, hence contributing to the massive water loss along the cryptvillus axis. In the same BBM preparations, rotavirus failed to stimulate the Cl(-) transport activities (Cl(-)/H(+) symport, Cl(-)/anion exchange and voltage-activated Cl(-) conductance) at the crypt level, but not at the villus level, questioning, therefore, the origin of net chloride secretion. We propose that the chloride carrier might function in both normal (absorption) and reversed (secretion) modes in villi, depending on the direction of the chloride electrochemical gradient resulting from rotavirus infection, agreeing with our results that rotavirus accelerated both Cl(-) influx and Cl(-) efflux rates across villi BBM." @default.
• W1963997977 created "2016-06-24" @default.
• W1963997977 creator A5000983256 @default.
• W1963997977 creator A5059299406 @default.
• W1963997977 creator A5088329555 @default.
• W1963997977 date "2006-01-01" @default.
• W1963997977 modified "2023-10-01" @default.
• W1963997977 title "Mechanisms of Net Chloride Secretion During Rotavirus Diarrhea in Young Rabbits : Do Intestinal Villi Secrete Chloride?" @default.
• W1963997977 cites W1752632498 @default.
• W1963997977 cites W1871762472 @default.
• W1963997977 cites W1967709045 @default.
• W1963997977 cites W1975134146 @default.
• W1963997977 cites W1978633542 @default.
• W1963997977 cites W1982620154 @default.
• W1963997977 cites W1982972448 @default.
• W1963997977 cites W1990451226 @default.
• W1963997977 cites W1997728373 @default.
• W1963997977 cites W2024666229 @default.
• W1963997977 cites W2030028204 @default.
• W1963997977 cites W2031464857 @default.
• W1963997977 cites W2036427272 @default.
• W1963997977 cites W2036880458 @default.
• W1963997977 cites W2037528560 @default.
• W1963997977 cites W2039235628 @default.
• W1963997977 cites W2039978157 @default.
• W1963997977 cites W2051761862 @default.
• W1963997977 cites W2053821457 @default.
• W1963997977 cites W2062345246 @default.
• W1963997977 cites W2069547775 @default.
• W1963997977 cites W2079459330 @default.
• W1963997977 cites W2089209196 @default.
• W1963997977 cites W2117856246 @default.
• W1963997977 cites W2123282327 @default.
• W1963997977 cites W2151904980 @default.
• W1963997977 cites W2156223714 @default.
• W1963997977 cites W2163702256 @default.
• W1963997977 cites W2163892669 @default.
• W1963997977 cites W2170372540 @default.
• W1963997977 cites W2170444144 @default.
• W1963997977 cites W2188983291 @default.
• W1963997977 cites W2231512944 @default.
• W1963997977 cites W2236272511 @default.
• W1963997977 cites W2260928564 @default.
• W1963997977 cites W2308052730 @default.
• W1963997977 cites W2410629182 @default.
• W1963997977 cites W2425989567 @default.
• W1963997977 cites W2469024394 @default.
• W1963997977 cites W4206487385 @default.
• W1963997977 cites W4247870281 @default.
• W1963997977 cites W89204759 @default.
• W1963997977 doi "https://doi.org/10.1159/000095174" @default.
• W1963997977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16914895" @default.
• W1963997977 hasPublicationYear "2006" @default.
• W1963997977 type Work @default.
• W1963997977 sameAs 1963997977 @default.
• W1963997977 citedByCount "12" @default.
• W1963997977 countsByYear W19639979772012 @default.
• W1963997977 countsByYear W19639979772015 @default.
• W1963997977 countsByYear W19639979772018 @default.
• W1963997977 countsByYear W19639979772019 @default.
• W1963997977 countsByYear W19639979772020 @default.
• W1963997977 crossrefType "journal-article" @default.
• W1963997977 hasAuthorship W1963997977A5000983256 @default.
• W1963997977 hasAuthorship W1963997977A5059299406 @default.
• W1963997977 hasAuthorship W1963997977A5088329555 @default.
• W1963997977 hasBestOaLocation W19639979771 @default.
• W1963997977 hasConcept C104317684 @default.
• W1963997977 hasConcept C120405084 @default.
• W1963997977 hasConcept C126322002 @default.
• W1963997977 hasConcept C130316041 @default.
• W1963997977 hasConcept C134018914 @default.
• W1963997977 hasConcept C149011108 @default.
• W1963997977 hasConcept C178790620 @default.
• W1963997977 hasConcept C185592680 @default.
• W1963997977 hasConcept C188053792 @default.
• W1963997977 hasConcept C2777882243 @default.
• W1963997977 hasConcept C2778695967 @default.
• W1963997977 hasConcept C2779604457 @default.
• W1963997977 hasConcept C2779802037 @default.
• W1963997977 hasConcept C2780091579 @default.
• W1963997977 hasConcept C2781077229 @default.
• W1963997977 hasConcept C2781367151 @default.
• W1963997977 hasConcept C3018436504 @default.
• W1963997977 hasConcept C41625074 @default.
• W1963997977 hasConcept C49039625 @default.
• W1963997977 hasConcept C529295009 @default.
• W1963997977 hasConcept C537181965 @default.
• W1963997977 hasConcept C5426402 @default.
• W1963997977 hasConcept C54355233 @default.
• W1963997977 hasConcept C55493867 @default.
• W1963997977 hasConcept C56906281 @default.
• W1963997977 hasConcept C66090201 @default.
• W1963997977 hasConcept C71924100 @default.
• W1963997977 hasConcept C86803240 @default.
• W1963997977 hasConceptScore W1963997977C104317684 @default.
• W1963997977 hasConceptScore W1963997977C120405084 @default.
• W1963997977 hasConceptScore W1963997977C126322002 @default.
• W1963997977 hasConceptScore W1963997977C130316041 @default.

• next