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- W1964028287 abstract "A potent inhibitor of the JmjC histone lysine demethylase KDM2A (compound 35, pIC50 7.2) with excellent selectivity over representatives from other KDM subfamilies has been developed; the discovery that a triazolopyridine compound binds to the active site of JmjC KDMs was followed by optimisation of the triazole substituent for KDM2A inhibition and selectivity." @default.
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- W1964028287 date "2014-01-01" @default.
- W1964028287 modified "2023-10-06" @default.
- W1964028287 title "Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor" @default.
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- W1964028287 doi "https://doi.org/10.1039/c4md00291a" @default.
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