Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964077965> ?p ?o ?g. }
- W1964077965 endingPage "2157" @default.
- W1964077965 startingPage "2157" @default.
- W1964077965 abstract "Systematic studies were performed on the biological perturbations in metabolic phenotype responding to protein-energy malnutrition through global metabolic profiling analysis, in combination with pattern recognition. The malnutrition rat model was established through five weeks of strict diet restriction, and the metabonome data obtained from gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) were integrated to approximate the comprehensive metabolic signature. Principal component analysis and orthogonal projection to latent structure analysis were used for the classification of metabolic phenotypes and discovery of differentiating metabolites. The perturbations in the urine profiles of malnourished rats were marked by higher levels of creatine, threitol, pyroglutamic acid, gluconic acid and kynurenic acid, as well as decreased levels of succinic acid, cis-aconitic acid, citric acid, isocitric acid, threonic acid, trimethylglycine, N-methylnicotinic acid and uric acid. The alterations in these metabolites were associated with perturbations in energy metabolism, carbohydrate, amino acid, and fatty acid metabolism, purine metabolism, cofactor and vitamin metabolism, in response to protein and energy malnutrition. Our findings show the integration of GC-MS and LC-MS techniques for untargeted metabolic profiling analysis was promising for nutriology." @default.
- W1964077965 created "2016-06-24" @default.
- W1964077965 creator A5001405633 @default.
- W1964077965 creator A5031458824 @default.
- W1964077965 creator A5049715698 @default.
- W1964077965 creator A5050707734 @default.
- W1964077965 creator A5051749405 @default.
- W1964077965 creator A5057634138 @default.
- W1964077965 creator A5059628106 @default.
- W1964077965 creator A5060239106 @default.
- W1964077965 creator A5074239091 @default.
- W1964077965 creator A5074290365 @default.
- W1964077965 date "2010-01-01" @default.
- W1964077965 modified "2023-09-28" @default.
- W1964077965 title "Urinary metabonomics study in a rat model in response to protein-energy malnutrition by using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry" @default.
- W1964077965 cites W1968813633 @default.
- W1964077965 cites W1980031054 @default.
- W1964077965 cites W1981643561 @default.
- W1964077965 cites W1983649481 @default.
- W1964077965 cites W1986704810 @default.
- W1964077965 cites W1990745503 @default.
- W1964077965 cites W1994397833 @default.
- W1964077965 cites W2003414488 @default.
- W1964077965 cites W2007343986 @default.
- W1964077965 cites W2013036395 @default.
- W1964077965 cites W2015776405 @default.
- W1964077965 cites W2016997751 @default.
- W1964077965 cites W2017932539 @default.
- W1964077965 cites W2024862672 @default.
- W1964077965 cites W2032865993 @default.
- W1964077965 cites W2042475696 @default.
- W1964077965 cites W2044563035 @default.
- W1964077965 cites W2050135062 @default.
- W1964077965 cites W2052716733 @default.
- W1964077965 cites W2060952451 @default.
- W1964077965 cites W2062447017 @default.
- W1964077965 cites W2062551369 @default.
- W1964077965 cites W2066896487 @default.
- W1964077965 cites W2070147923 @default.
- W1964077965 cites W2075397364 @default.
- W1964077965 cites W2084858824 @default.
- W1964077965 cites W2093852546 @default.
- W1964077965 cites W2109674683 @default.
- W1964077965 cites W2118094282 @default.
- W1964077965 cites W2123727902 @default.
- W1964077965 cites W2147327789 @default.
- W1964077965 cites W2155680682 @default.
- W1964077965 cites W2156009645 @default.
- W1964077965 cites W2168661366 @default.
- W1964077965 cites W2169128690 @default.
- W1964077965 doi "https://doi.org/10.1039/c005291d" @default.
- W1964077965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20717558" @default.
- W1964077965 hasPublicationYear "2010" @default.
- W1964077965 type Work @default.
- W1964077965 sameAs 1964077965 @default.
- W1964077965 citedByCount "31" @default.
- W1964077965 countsByYear W19640779652012 @default.
- W1964077965 countsByYear W19640779652013 @default.
- W1964077965 countsByYear W19640779652014 @default.
- W1964077965 countsByYear W19640779652015 @default.
- W1964077965 countsByYear W19640779652016 @default.
- W1964077965 countsByYear W19640779652017 @default.
- W1964077965 countsByYear W19640779652018 @default.
- W1964077965 countsByYear W19640779652020 @default.
- W1964077965 countsByYear W19640779652021 @default.
- W1964077965 countsByYear W19640779652022 @default.
- W1964077965 countsByYear W19640779652023 @default.
- W1964077965 crossrefType "journal-article" @default.
- W1964077965 hasAuthorship W1964077965A5001405633 @default.
- W1964077965 hasAuthorship W1964077965A5031458824 @default.
- W1964077965 hasAuthorship W1964077965A5049715698 @default.
- W1964077965 hasAuthorship W1964077965A5050707734 @default.
- W1964077965 hasAuthorship W1964077965A5051749405 @default.
- W1964077965 hasAuthorship W1964077965A5057634138 @default.
- W1964077965 hasAuthorship W1964077965A5059628106 @default.
- W1964077965 hasAuthorship W1964077965A5060239106 @default.
- W1964077965 hasAuthorship W1964077965A5074239091 @default.
- W1964077965 hasAuthorship W1964077965A5074290365 @default.
- W1964077965 hasConcept C162356407 @default.
- W1964077965 hasConcept C185592680 @default.
- W1964077965 hasConcept C192989942 @default.
- W1964077965 hasConcept C205345274 @default.
- W1964077965 hasConcept C21565614 @default.
- W1964077965 hasConcept C2776706248 @default.
- W1964077965 hasConcept C2776841986 @default.
- W1964077965 hasConcept C43617362 @default.
- W1964077965 hasConcept C515207424 @default.
- W1964077965 hasConcept C55493867 @default.
- W1964077965 hasConcept C62231903 @default.
- W1964077965 hasConceptScore W1964077965C162356407 @default.
- W1964077965 hasConceptScore W1964077965C185592680 @default.
- W1964077965 hasConceptScore W1964077965C192989942 @default.
- W1964077965 hasConceptScore W1964077965C205345274 @default.
- W1964077965 hasConceptScore W1964077965C21565614 @default.
- W1964077965 hasConceptScore W1964077965C2776706248 @default.
- W1964077965 hasConceptScore W1964077965C2776841986 @default.
- W1964077965 hasConceptScore W1964077965C43617362 @default.
- W1964077965 hasConceptScore W1964077965C515207424 @default.