FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964097712> ?p ?o ?g. }

• W1964097712 endingPage "797" @default.
• W1964097712 startingPage "791" @default.
• W1964097712 abstract "Placebos are known to induce analgesia through the activation of μ-opioid receptors in some circumstances, such as after morphine pre-conditioning, an effect that is blocked by opioid antagonists. On the basis of the anti-opioid action of cholecystokinin, here we tested whether the activation of the cholecystokinin type-2 receptors abolishes opioid-induced placebo responses. The activation of the cholecystokinin type-2 receptors was performed by means of the agonist pentagastrin, and placebo responses were obtained after morphine pre-conditioning in an experimental human model of pain (tourniquet technique). Opioid-induced placebo responses were completely disrupted by pentagastrin administration. In addition, a high correlation between the response to morphine and the response to placebo was found, and this correlation was completely abolished by pentagastrin. These results show that the cholecystokinin-2 receptor agonist, pentagastrin, has the same effect as the μ-opioid receptor antagonist, naloxone, on placebo analgesia induced by morphine pre-conditioning, which suggests that the balance between cholecystokinergic and opioidergic systems is crucial in placebo responsiveness in pain. These findings also suggest that cholecystokinin type-2 receptor hyperactivity might be present in placebo non-responders." @default.
• W1964097712 created "2016-06-24" @default.
• W1964097712 creator A5013363780 @default.
• W1964097712 creator A5017581232 @default.
• W1964097712 creator A5054136549 @default.
• W1964097712 date "2010-10-08" @default.
• W1964097712 modified "2023-10-17" @default.
• W1964097712 title "Disruption of opioid-induced placebo responses by activation of cholecystokinin type-2 receptors" @default.
• W1964097712 cites W1967999836 @default.
• W1964097712 cites W1976846134 @default.
• W1964097712 cites W1984147433 @default.
• W1964097712 cites W1998993206 @default.
• W1964097712 cites W2011285008 @default.
• W1964097712 cites W2013302461 @default.
• W1964097712 cites W2019030815 @default.
• W1964097712 cites W2020014738 @default.
• W1964097712 cites W2026747063 @default.
• W1964097712 cites W2038955155 @default.
• W1964097712 cites W2067552820 @default.
• W1964097712 cites W2070268037 @default.
• W1964097712 cites W2079957063 @default.
• W1964097712 cites W2094347820 @default.
• W1964097712 cites W2119898297 @default.
• W1964097712 cites W2121355626 @default.
• W1964097712 cites W2125295858 @default.
• W1964097712 cites W2130690736 @default.
• W1964097712 cites W2135382170 @default.
• W1964097712 cites W2136157116 @default.
• W1964097712 cites W2136602820 @default.
• W1964097712 cites W2148993214 @default.
• W1964097712 cites W2157903425 @default.
• W1964097712 doi "https://doi.org/10.1007/s00213-010-2037-y" @default.
• W1964097712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20931328" @default.
• W1964097712 hasPublicationYear "2010" @default.
• W1964097712 type Work @default.
• W1964097712 sameAs 1964097712 @default.
• W1964097712 citedByCount "58" @default.
• W1964097712 countsByYear W19640977122012 @default.
• W1964097712 countsByYear W19640977122013 @default.
• W1964097712 countsByYear W19640977122014 @default.
• W1964097712 countsByYear W19640977122015 @default.
• W1964097712 countsByYear W19640977122016 @default.
• W1964097712 countsByYear W19640977122017 @default.
• W1964097712 countsByYear W19640977122018 @default.
• W1964097712 countsByYear W19640977122019 @default.
• W1964097712 countsByYear W19640977122020 @default.
• W1964097712 countsByYear W19640977122021 @default.
• W1964097712 countsByYear W19640977122022 @default.
• W1964097712 countsByYear W19640977122023 @default.
• W1964097712 crossrefType "journal-article" @default.
• W1964097712 hasAuthorship W1964097712A5013363780 @default.
• W1964097712 hasAuthorship W1964097712A5017581232 @default.
• W1964097712 hasAuthorship W1964097712A5054136549 @default.
• W1964097712 hasBestOaLocation W19640977122 @default.
• W1964097712 hasConcept C107539642 @default.
• W1964097712 hasConcept C126322002 @default.
• W1964097712 hasConcept C134018914 @default.
• W1964097712 hasConcept C142724271 @default.
• W1964097712 hasConcept C170493617 @default.
• W1964097712 hasConcept C204787440 @default.
• W1964097712 hasConcept C27081682 @default.
• W1964097712 hasConcept C2777389121 @default.
• W1964097712 hasConcept C2777504413 @default.
• W1964097712 hasConcept C2777593968 @default.
• W1964097712 hasConcept C2778750930 @default.
• W1964097712 hasConcept C2778938600 @default.
• W1964097712 hasConcept C2779004600 @default.
• W1964097712 hasConcept C2779377912 @default.
• W1964097712 hasConcept C2779422922 @default.
• W1964097712 hasConcept C2779886867 @default.
• W1964097712 hasConcept C2781063702 @default.
• W1964097712 hasConcept C3019590667 @default.
• W1964097712 hasConcept C32110497 @default.
• W1964097712 hasConcept C71924100 @default.
• W1964097712 hasConcept C98274493 @default.
• W1964097712 hasConceptScore W1964097712C107539642 @default.
• W1964097712 hasConceptScore W1964097712C126322002 @default.
• W1964097712 hasConceptScore W1964097712C134018914 @default.
• W1964097712 hasConceptScore W1964097712C142724271 @default.
• W1964097712 hasConceptScore W1964097712C170493617 @default.
• W1964097712 hasConceptScore W1964097712C204787440 @default.
• W1964097712 hasConceptScore W1964097712C27081682 @default.
• W1964097712 hasConceptScore W1964097712C2777389121 @default.
• W1964097712 hasConceptScore W1964097712C2777504413 @default.
• W1964097712 hasConceptScore W1964097712C2777593968 @default.
• W1964097712 hasConceptScore W1964097712C2778750930 @default.
• W1964097712 hasConceptScore W1964097712C2778938600 @default.
• W1964097712 hasConceptScore W1964097712C2779004600 @default.
• W1964097712 hasConceptScore W1964097712C2779377912 @default.
• W1964097712 hasConceptScore W1964097712C2779422922 @default.
• W1964097712 hasConceptScore W1964097712C2779886867 @default.
• W1964097712 hasConceptScore W1964097712C2781063702 @default.
• W1964097712 hasConceptScore W1964097712C3019590667 @default.
• W1964097712 hasConceptScore W1964097712C32110497 @default.
• W1964097712 hasConceptScore W1964097712C71924100 @default.
• W1964097712 hasConceptScore W1964097712C98274493 @default.
• W1964097712 hasIssue "4" @default.
• W1964097712 hasLocation W19640977121 @default.

• next