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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964125655> ?p ?o ?g. }

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• W1964125655 abstract "Few methods are available for mapping the local structure of DNA throughout a genome. The hydroxyl radical cleavage pattern is a measure of the local variation in solvent-accessible surface area of duplex DNA, and thus provides information on the local shape and structure of DNA. We report the construction of a relational database, ORChID (OH Radical Cleavage Intensity Database), that contains extensive hydroxyl radical cleavage data produced from two DNA libraries. We have used the ORChID database to develop a set of algorithms that are capable of predicting the hydroxyl radical cleavage pattern of a DNA sequence of essentially any length, to high accuracy. We have used the prediction algorithm to produce a structural map of the 30 Mb of the ENCODE regions of the human genome." @default.
• W1964125655 created "2016-06-24" @default.
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• W1964125655 date "2007-06-01" @default.
• W1964125655 modified "2023-10-16" @default.
• W1964125655 title "Construction of a genome-scale structural map at single-nucleotide resolution" @default.
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• W1964125655 doi "https://doi.org/10.1101/gr.6073107" @default.
• W1964125655 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1891353" @default.
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