Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964272429> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1964272429 endingPage "1144" @default.
- W1964272429 startingPage "1141" @default.
- W1964272429 abstract "We have developed an affinity labeling technique that uses disuccinimidyl suberate to covalently cross-link [125I]somatomedin-C (Sm-C) to specific binding proteins in rat serum. Normal rat serum contains four major classes of intensely labeled [125I]Sm-C-binding protein complexes which are sensitive to competition with unlabeled Sm-C with relative molecular masses of 95, 49, 36–33, and 26–23 K. In addition, less intensely labeled complexes are observed migrating between 175 and 115 K. Of the Sm-C binding complexes observed in normal serum, hypophysectomized (hypox) serum contains only an intensely labeled 36-33-K complex and a faint 49-K complex. Chronic administration of ovine (100 ng, ip, daily) to hypox rats induces the 95-K complex and possibly complexes between 175–115 K. With increasing duration of treatment, these complexes as well as the 49-K complex appear to increase in intensity. Binding proteins in both hypox and normal sera do not appear to distinguish between Sms, since both unlabeled Sm-C and multiplication-stimulating activity were equally potent in competing with [125I]Sm-C for binding. This affinity labeling technique appears t o be a useful investigative tool to study the physiology and structure of Sm-binding proteins. (Endocrinology114: 1141, 1984)" @default.
- W1964272429 created "2016-06-24" @default.
- W1964272429 creator A5060905257 @default.
- W1964272429 creator A5066849052 @default.
- W1964272429 date "1984-04-01" @default.
- W1964272429 modified "2023-10-16" @default.
- W1964272429 title "Affinity Labeled Somatomedin-C-Binding Proteins in Rat Sera*" @default.
- W1964272429 cites W180238663 @default.
- W1964272429 cites W1978916721 @default.
- W1964272429 cites W1992829214 @default.
- W1964272429 cites W2008115139 @default.
- W1964272429 cites W2010577174 @default.
- W1964272429 cites W2018002682 @default.
- W1964272429 cites W2020635408 @default.
- W1964272429 cites W2022698715 @default.
- W1964272429 cites W2048727629 @default.
- W1964272429 cites W2083406280 @default.
- W1964272429 cites W2100837269 @default.
- W1964272429 cites W2164929274 @default.
- W1964272429 cites W2169916499 @default.
- W1964272429 cites W2408477582 @default.
- W1964272429 doi "https://doi.org/10.1210/endo-114-4-1141" @default.
- W1964272429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6200313" @default.
- W1964272429 hasPublicationYear "1984" @default.
- W1964272429 type Work @default.
- W1964272429 sameAs 1964272429 @default.
- W1964272429 citedByCount "37" @default.
- W1964272429 countsByYear W19642724292022 @default.
- W1964272429 crossrefType "journal-article" @default.
- W1964272429 hasAuthorship W1964272429A5060905257 @default.
- W1964272429 hasAuthorship W1964272429A5066849052 @default.
- W1964272429 hasConcept C104317684 @default.
- W1964272429 hasConcept C107824862 @default.
- W1964272429 hasConcept C126322002 @default.
- W1964272429 hasConcept C134018914 @default.
- W1964272429 hasConcept C146543888 @default.
- W1964272429 hasConcept C170493617 @default.
- W1964272429 hasConcept C185592680 @default.
- W1964272429 hasConcept C2775960820 @default.
- W1964272429 hasConcept C2780104272 @default.
- W1964272429 hasConcept C55493867 @default.
- W1964272429 hasConcept C71315377 @default.
- W1964272429 hasConcept C71924100 @default.
- W1964272429 hasConcept C80862487 @default.
- W1964272429 hasConcept C86339819 @default.
- W1964272429 hasConcept C86803240 @default.
- W1964272429 hasConcept C94966510 @default.
- W1964272429 hasConceptScore W1964272429C104317684 @default.
- W1964272429 hasConceptScore W1964272429C107824862 @default.
- W1964272429 hasConceptScore W1964272429C126322002 @default.
- W1964272429 hasConceptScore W1964272429C134018914 @default.
- W1964272429 hasConceptScore W1964272429C146543888 @default.
- W1964272429 hasConceptScore W1964272429C170493617 @default.
- W1964272429 hasConceptScore W1964272429C185592680 @default.
- W1964272429 hasConceptScore W1964272429C2775960820 @default.
- W1964272429 hasConceptScore W1964272429C2780104272 @default.
- W1964272429 hasConceptScore W1964272429C55493867 @default.
- W1964272429 hasConceptScore W1964272429C71315377 @default.
- W1964272429 hasConceptScore W1964272429C71924100 @default.
- W1964272429 hasConceptScore W1964272429C80862487 @default.
- W1964272429 hasConceptScore W1964272429C86339819 @default.
- W1964272429 hasConceptScore W1964272429C86803240 @default.
- W1964272429 hasConceptScore W1964272429C94966510 @default.
- W1964272429 hasIssue "4" @default.
- W1964272429 hasLocation W19642724291 @default.
- W1964272429 hasLocation W19642724292 @default.
- W1964272429 hasOpenAccess W1964272429 @default.
- W1964272429 hasPrimaryLocation W19642724291 @default.
- W1964272429 hasRelatedWork W2018368842 @default.
- W1964272429 hasRelatedWork W2053449558 @default.
- W1964272429 hasRelatedWork W2061429094 @default.
- W1964272429 hasRelatedWork W2063619316 @default.
- W1964272429 hasRelatedWork W2065655537 @default.
- W1964272429 hasRelatedWork W2080815888 @default.
- W1964272429 hasRelatedWork W2126532023 @default.
- W1964272429 hasRelatedWork W2127054680 @default.
- W1964272429 hasRelatedWork W4245771949 @default.
- W1964272429 hasRelatedWork W2109473735 @default.
- W1964272429 hasVolume "114" @default.
- W1964272429 isParatext "false" @default.
- W1964272429 isRetracted "false" @default.
- W1964272429 magId "1964272429" @default.
- W1964272429 workType "article" @default.