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• W1964295476 abstract "The effects of losartan potassium, an AT 1 angiotensin receptor antagonist on lipid peroxidation and activities of superoxide dismutase and catalase in the kidney of streptozotocin-diabetic rats were studied. Experimental diabetes resulted in an increase of malondialdehyde content of the kidneys and decreases of superoxide dismutase and catalase activity in this organ after 6 and 12 weeks. Administration of losartan potassium (1 mg/kg body weight in the drinking water) prevented the increase on malondialdehyde level and normalized the activities of antioxidant enzymes after both 6 and 12 weeks of the experiment. These results demonstrate an antioxidative effect of losartan potassium in diabetic rats in vivo." @default.
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• W1964295476 date "2000-02-01" @default.
• W1964295476 modified "2023-10-18" @default.
• W1964295476 title "Effect of AT1 angiotensin receptor antagonist on lipid peroxidation and antioxidative defense in diabetic kidney" @default.
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• W1964295476 doi "https://doi.org/10.1016/s0928-4680(99)00028-0" @default.
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